Other names published for MEC1: ESR1, SAD3, RAD31, YBR136W
MEC1 LITERATURE TOPICS
- Curated Literature
- Genetics/Cell Biology
- Nucleic Acid Information
- Gene Product Information
- Related Genes/Proteins
- Research Aids
- Genome-wide Analysis
- Proteome-wide Analysis
- Other Topics
- Additional Information
MEC1 - Substrates/Ligands/Cofactors (38)
| Reference | Other Genes Addressed |
|---|---|
| Lai AC, et al. (2012) Predicting kinase substrates using conservation of local motif density. Bioinformatics 28(7):962-9 | |
| Chen X, et al. (2011) Cell cycle regulation of DNA double-strand break end resection by Cdk1-dependent Dna2 phosphorylation.LID - 10.1038/nsmb.2105 [doi] Nat Struct Mol Biol () | |
| Searle JS, et al. (2011) Proteins in the Nutrient-Sensing and DNA Damage Checkpoint Pathways Cooperate to Restrain Mitotic Progression following DNA Damage. PLoS Genet 7(7):e1002176 | |
| Chen SH, et al. (2010) A proteome-wide analysis of kinase-substrate network in the DNA damage response. J Biol Chem 285(17):12803-12 | |
| Janke R, et al. (2010) A truncated DNA-damage-signaling response is activated after DSB formation in the G1 phase of Saccharomyces cerevisiae. Nucleic Acids Res 38(7):2302-13 | |
| Toh GW, et al. (2010) Mec1/Tel1-dependent phosphorylation of Slx4 stimulates Rad1-Rad10-dependent cleavage of non-homologous DNA tails. DNA Repair (Amst) 9(6):718-26 | |
| Chen SH and Zhou H (2009) Reconstitution of Rad53 Activation by Mec1 through Adaptor Protein Mrc1. J Biol Chem 284(28):18593-604 | |
| Pages V, et al. (2009) Role of DNA damage-induced replication checkpoint in promoting lesion bypass by translesion synthesis in yeast. Genes Dev 23(12):1438-49 | |
| Truman AW, et al. (2009) Mechanism of Mpk1 mitogen-activated protein kinase binding to the Swi4 transcription factor and its regulation by a novel caffeine-induced phosphorylation. Mol Cell Biol 29(24):6449-61 | |
| Usui T, et al. (2009) Maintenance of the DNA-damage checkpoint requires DNA-damage-induced mediator protein oligomerization. Mol Cell 33(2):147-59 | |
| Mordes DA, et al. (2008) Dpb11 activates the Mec1-Ddc2 complex. Proc Natl Acad Sci U S A 105(48):18730-4 | |
| Kim JA, et al. (2007) Heterochromatin is refractory to gamma-H2AX modification in yeast and mammals. J Cell Biol 178(2):209-18 | |
| Morrison AJ, et al. (2007) Mec1/Tel1 phosphorylation of the INO80 chromatin remodeling complex influences DNA damage checkpoint responses. Cell 130(3):499-511 | |
| Thaminy S, et al. (2007) Hst3 Is Regulated by Mec1-dependent Proteolysis and Controls the S Phase Checkpoint and Sister Chromatid Cohesion by Deacetylating Histone H3 at Lysine 56. J Biol Chem 282(52):37805-14 | |
| Bashkirov VI, et al. (2006) DNA damage-induced phosphorylation of Rad55 protein as a sentinel for DNA damage checkpoint activation in S. cerevisiae. Methods Enzymol 409:166-82 | |
| Chin JK, et al. (2006) Esc4/Rtt107 and the control of recombination during replication. DNA Repair (Amst) 5(5):618-28 | |
| Javaheri A, et al. (2006) Yeast G1 DNA damage checkpoint regulation by H2A phosphorylation is independent of chromatin remodeling. Proc Natl Acad Sci U S A 103(37):13771-6 | |
| Li J, et al. (2006) Saccharomyces cerevisiae Mer2, Mei4 and Rec114 form a complex required for meiotic double-strand break formation. Genetics 173(4):1969-81 | |
| Ira G, et al. (2004) DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1. Nature 431(7011):1011-7 | |
| Naiki T, et al. (2004) Association of Rad9 with double-strand breaks through a Mec1-dependent mechanism. Mol Cell Biol 24(8):3277-85 | |
| Pike BL, et al. (2004) Mdt1, a novel Rad53 FHA1 domain-interacting protein, modulates DNA damage tolerance and G(2)/M cell cycle progression in Saccharomyces cerevisiae. Mol Cell Biol 24(7):2779-88 | |
| Rouse J (2004) Esc4p, a new target of Mec1p (ATR), promotes resumption of DNA synthesis after DNA damage. EMBO J 23(5):1188-97 | |
| Agarwal R, et al. (2003) Two distinct pathways for inhibiting pds1 ubiquitination in response to DNA damage. J Biol Chem 278(45):45027-33 | |
| Brinkworth RI, et al. (2003) Structural basis and prediction of substrate specificity in protein serine/threonine kinases. Proc Natl Acad Sci U S A 100(1):74-9 | |
| Mallory JC, et al. (2003) Amino acid changes in Xrs2p, Dun1p, and Rfa2p that remove the preferred targets of the ATM family of protein kinases do not affect DNA repair or telomere length in Saccharomyces cerevisiae. DNA Repair (Amst) 2(9):1041-64 | |
| Kim EM, et al. (2002) Phosphorylation of Rph1, a damage-responsive repressor of PHR1 in Saccharomyces cerevisiae, is dependent upon Rad53 kinase. Nucleic Acids Res 30(3):643-8 | |
| Schwartz MF, et al. (2002) Rad9 phosphorylation sites couple Rad53 to the Saccharomyces cerevisiae DNA damage checkpoint. Mol Cell 9(5):1055-65 | |
| Kondo T, et al. (2001) Recruitment of Mec1 and Ddc1 checkpoint proteins to double-strand breaks through distinct mechanisms. Science 294(5543):867-70 | |
| Leroy C, et al. (2001) Silent repair accounts for cell cycle specificity in the signaling of oxidative DNA lesions. EMBO J 20(11):2896-906 | |
| Melo JA, et al. (2001) Two checkpoint complexes are independently recruited to sites of DNA damage in vivo. Genes Dev 15(21):2809-21 |




