UBC4/YBR082C Literature Guide Help

Other names published for UBC4: E2 ubiquitin-conjugating protein UBC4, YBR082C

UBC4 - Substrates/Ligands/Cofactors (23)

ReferenceOther Genes Addressed
Ha SW, et al.  (2012) The N-terminal domain of Rpn4 serves as a portable ubiquitin-independent degron and is recognized by specific 19S RP subunits. Biochem Biophys Res Commun 419(2):226-31
Rabut G, et al.  (2011) The TFIIH Subunit Tfb3 Regulates Cullin Neddylation. Mol Cell 43(3):488-95
Hwang CS, et al.  (2010) The N-end rule pathway is mediated by a complex of the RING-type Ubr1 and HECT-type Ufd4 ubiquitin ligases. Nat Cell Biol 12(12):1177-85
Nixon CE, et al.  (2010) Degradation of the Saccharomyces cerevisiae mating-type regulator alpha1: genetic dissection of cis-determinants and trans-acting pathways. Genetics 185(2):497-511
Ossareh-Nazari B, et al.  (2010) The Rsp5 ubiquitin ligase and the AAA-ATPase Cdc48 control the ubiquitin-mediated degradation of the COPII component Sec23. Exp Cell Res 316(20):3351-7
Sadowski M, et al.  (2010) Molecular basis for lysine specificity in the yeast ubiquitin-conjugating enzyme Cdc34. Mol Cell Biol 30(10):2316-29
Lundh F, et al.  (2009) Molecular mechanisms controlling phosphate-induced downregulation of the yeast Pho84 phosphate transporter. Biochemistry 48(21):4497-505
Prakash S, et al.  (2009) Substrate selection by the proteasome during degradation of protein complexes. Nat Chem Biol 5(1):29-36
Choi E, et al.  (2008) Unique D Box and KEN Box Sequences Limit Ubiquitination of Acm1 and Promote Pseudosubstrate Inhibition of the Anaphase-promoting Complex. J Biol Chem 283(35):23701-10
Metzger MB, et al.  (2008) Degradation of a Cytosolic Protein Requires Endoplasmic Reticulum-associated Degradation Machinery. J Biol Chem 283(47):32302-16
Panasenko O, et al.  (2006) The yeast Ccr4-Not complex controls ubiquitination of the nascent-associated polypeptide (NAC-EGD) complex. J Biol Chem 281(42):31389-98
Chuang SM and Madura K  (2005) Saccharomyces cerevisiae Ub-conjugating enzyme Ubc4 binds the proteasome in the presence of translationally damaged proteins. Genetics 171(4):1477-84
Passmore LA, et al.  (2005) Purification and assay of the budding yeast anaphase-promoting complex. Methods Enzymol 398():195-219
Furuchi T, et al.  (2002) Overexpression of the ubiquitin-conjugating enzyme Cdc34 confers resistance to methylmercury in Saccharomyces cerevisiae. Mol Pharmacol 61(4):738-41
Purdue PE and Lazarow PB  (2001) Pex18p is constitutively degraded during peroxisome biogenesis. J Biol Chem 276(50):47684-9
Ortolan TG, et al.  (2000) The DNA repair protein rad23 is a negative regulator of multi-ubiquitin chain assembly. Nat Cell Biol 2(9):601-8
Loidl G, et al.  (1999) Bivalency as a principle for proteasome inhibition. Proc Natl Acad Sci U S A 96(10):5418-22
Hicke L and Riezman H  (1996) Ubiquitination of a yeast plasma membrane receptor signals its ligand-stimulated endocytosis. Cell 84(2):277-87
Gwozd CS, et al.  (1995) The yeast UBC4 ubiquitin conjugating enzyme monoubiquitinates itself in vivo: evidence for an E2-E2 homointeraction. Biochemistry 34(19):6296-302
Sadis S, et al.  (1995) Synthetic signals for ubiquitin-dependent proteolysis. Mol Cell Biol 15(8):4086-94
Cook WJ, et al.  (1993) Tertiary structures of class I ubiquitin-conjugating enzymes are highly conserved: crystal structure of yeast Ubc4. Biochemistry 32(50):13809-17
Parag HA, et al.  (1993) Selective ubiquitination of calmodulin by UBC4 and a putative ubiquitin protein ligase (E3) from Saccharomyces cerevisiae. FEBS Lett 325(3):242-6
Seufert W and Jentsch S  (1990) Ubiquitin-conjugating enzymes UBC4 and UBC5 mediate selective degradation of short-lived and abnormal proteins. EMBO J 9(2):543-50