CYC3/YAL039C Literature Guide Help

Other names published for CYC3: cytochrome c heme lyase, CCHL, holocytochrome c synthase CYC3, YAL039C

CYC3 - Substrates/Ligands/Cofactors (9)

ReferenceOther Genes Addressed
Moore RL, et al.  (2011) Mitochondrial cytochrome c synthase: CP motifs are not necessary for heme attachment to apocytochrome c. FEBS Lett 585(21):3415-9
Fulop V, et al.  (2009) Structure of a trypanosomatid mitochondrial cytochrome c with heme attached via only one thioether bond and implications for the substrate recognition requirements of heme lyase. FEBS J 276(10):2822-2832
Bernard DG, et al.  (2003) Overlapping specificities of the mitochondrial cytochrome c and c1 heme lyases. J Biol Chem 278(50):49732-42
Steiner H, et al.  (1996) Heme binding to a conserved Cys-Pro-Val motif is crucial for the catalytic function of mitochondrial heme lyases. J Biol Chem 271(51):32605-11
Dumont ME, et al.  (1991) Role of cytochrome c heme lyase in mitochondrial import and accumulation of cytochrome c in Saccharomyces cerevisiae. Mol Cell Biol 11(11):5487-96
Nicholson DW and Neupert W  (1989) Import of cytochrome c into mitochondria: reduction of heme, mediated by NADH and flavin nucleotides, is obligatory for its covalent linkage to apocytochrome c. Proc Natl Acad Sci U S A 86(12):4340-4
Visco C, et al.  (1985) On the specificity of cytochrome c synthetase in recognition of the amino acid sequence of apocytochrome c. J Biol Chem 260(10):6133-8
Taniuchi H, et al.  (1983) Evidence for formation of two thioether bonds to link heme to apocytochrome c by partially purified cytochrome c synthetase. J Biol Chem 258(18):10963-6
Veloso D, et al.  (1981) Formation of a cytochrome c-like species from horse apoprotein and hemin catalyzed by yeast mitochondrial cytochrome c synthetase. J Biol Chem 256(16):8646-51