VPS8/YAL002W Literature Guide Help

Other names published for VPS8: FUN15, VPT8, VPL8, YAL002W

VPS8 - Strains/Constructs (30)

ReferenceOther Genes Addressed
Lachmann J, et al.  (2012) The Msb3/Gyp3 GAP controls the activity of the Rab GTPases Vps21 and Ypt7 at endosomes and vacuoles. Mol Biol Cell 23(13):2516-26
Russell MR, et al.  (2012) Class E compartments form in response to ESCRT dysfunction in yeast due to hyperactivity of the Vps21 Rab GTPase. J Cell Sci 125(Pt 21):5208-20
Fell GL, et al.  (2011) Identification of yeast genes involved in k homeostasis: loss of membrane traffic genes affects k uptake. G3 (Bethesda) 1(1):43-56
North M, et al.  (2011) Genome-wide functional profiling reveals genes required for tolerance to benzene metabolites in yeast. PLoS One 6(8):e24205
Plemel RL, et al.  (2011) Subunit organization and Rab interactions of Vps-C protein complexes that control endolysosomal membrane traffic. Mol Biol Cell 22(8):1353-63
Reid RJ, et al.  (2011) Selective ploidy ablation, a high-throughput plasmid transfer protocol, identifies new genes affecting topoisomerase I-induced DNA damage. Genome Res 21(3):477-86
Mira NP, et al.  (2010) Genome-wide identification of Saccharomyces cerevisiae genes required for tolerance to acetic acid. Microb Cell Fact 9(1):79
Nordmann M, et al.  (2010) The Mon1-Ccz1 complex is the GEF of the late endosomal Rab7 homolog Ypt7. Curr Biol 20(18):1654-9
Ostrowicz CW, et al.  (2010) Defined subunit arrangement and rab interactions are required for functionality of the HOPS tethering complex. Traffic 11(10):1334-46
Pawelec A, et al.  (2010) Mapping of Vps21 and HOPS binding sites in Vps8 and effect of binding site mutants on endocytic trafficking. Eukaryot Cell 9(4):602-10
Angers CG and Merz AJ  (2009) HOPS interacts with Apl5 at the vacuole membrane and is required for consumption of AP-3 transport vesicles. Mol Biol Cell 20(21):4563-74
Markgraf DF, et al.  (2009) The CORVET Subunit Vps8 Cooperates with the Rab5 Homolog Vps21 to Induce Clustering of Late Endosomal Compartments. Mol Biol Cell 20(24):5276-89
Doostzadeh J, et al.  (2007) Chemical genomic profiling for identifying intracellular targets of toxicants producing Parkinson's disease. Toxicol Sci 95(1):182-7
Mulder KW, et al.  (2007) Modulation of Ubc4p/Ubc5p-Mediated Stress Responses by the RING-Finger-Dependent Ubiquitin-Protein Ligase Not4p in Saccharomyces cerevisiae. Genetics 176(1):181-92
Foote C and Nothwehr SF  (2006) The clathrin adaptor complex 1 directly binds to a sorting signal in Ste13p to reduce the rate of its trafficking to the late endosome of yeast. J Cell Biol 173(4):615-26
Agaphonov M, et al.  (2005) Defect of vacuolar protein sorting stimulates proteolytic processing of human urokinase-type plasminogen activator in the yeast Hansenula polymorpha. FEMS Yeast Res 5(11):1029-35
Krsmanovic T, et al.  (2005) Control of Ste6 recycling by ubiquitination in the early endocytic pathway in yeast. Mol Biol Cell 16(6):2809-21
Tong AH, et al.  (2004) Global mapping of the yeast genetic interaction network. Science 303(5659):808-13
Martinez M, et al.  (2003) Overexpression of genes involved in vesicular trafficking to the vacuole defends against lethal effects of oxidative damage. Cell Mol Biol (Noisy-le-grand) 49(7):1025-35
Hanson PK, et al.  (2002) NBD-labeled phosphatidylcholine enters the yeast vacuole via the pre-vacuolar compartment. J Cell Sci 115(Pt 13):2725-33
Luo Wj and Chang A  (2000) An endosome-to-plasma membrane pathway involved in trafficking of a mutant plasma membrane ATPase in yeast. Mol Biol Cell 11(2):579-92
Woolford CA, et al.  (1998) Genetic interaction with vps8-200 allows partial suppression of the vestigial vacuole phenotype caused by a pep5 mutation in Saccharomyces cerevisiae. Genetics 148(1):71-83
Luo W and Chang A  (1997) Novel genes involved in endosomal traffic in yeast revealed by suppression of a targeting-defective plasma membrane ATPase mutant. J Cell Biol 138(4):731-46
Chen YJ and Stevens TH  (1996) The VPS8 gene is required for localization and trafficking of the CPY sorting receptor in Saccharomyces cerevisiae. Eur J Cell Biol 70(4):289-97
Horazdovsky BF, et al.  (1996) A novel RING finger protein, Vps8p, functionally interacts with the small GTPase, Vps21p, to facilitate soluble vacuolar protein localization. J Biol Chem 271(52):33607-15
Rothman JH, et al.  (1989) Characterization of genes required for protein sorting and vacuolar function in the yeast Saccharomyces cerevisiae. EMBO J 8(7):2057-65
Banta LM, et al.  (1988) Organelle assembly in yeast: characterization of yeast mutants defective in vacuolar biogenesis and protein sorting. J Cell Biol 107(4):1369-83
Robinson JS, et al.  (1988) Protein sorting in Saccharomyces cerevisiae: isolation of mutants defective in the delivery and processing of multiple vacuolar hydrolases. Mol Cell Biol 8(11):4936-48
Bankaitis VA, et al.  (1986) Isolation of yeast mutants defective in protein targeting to the vacuole. Proc Natl Acad Sci U S A 83(23):9075-9
Rothman JH and Stevens TH  (1986) Protein sorting in yeast: mutants defective in vacuole biogenesis mislocalize vacuolar proteins into the late secretory pathway. Cell 47(6):1041-51