SIR2/YDL042C Literature Guide Help

Other names published for SIR2: MAR1, YDL042C

SIR2 - Strains/Constructs (240)

ReferenceOther Genes Addressed
Casatta N, et al.  (2013) Lack of Sir2 increases acetate consumption and decreases extracellular pro-aging factors. Biochim Biophys Acta 1833(3):593-601
Delaney JR, et al.  (2013) Stress profiling of longevity mutants identifies Afg3 as a mitochondrial determinant of cytoplasmic mRNA translation and aging. Aging Cell 12(1):156-66
Bheda P, et al.  (2012) Biotinylation of lysine method identifies acetylated histone H3 lysine 79 in Saccharomyces cerevisiae as a substrate for Sir2. Proc Natl Acad Sci U S A 109(16):E916-25
Cesarini E, et al.  (2012) H4K16 acetylation affects recombination and ncRNA transcription at rDNA in Saccharomyces cerevisiae. Mol Biol Cell 23(14):2770-81
Drobna E, et al.  (2012) Overexpression of the YAP1, PDE2, and STB3 genes enhances the tolerance of yeast to oxidative stress induced by 7-chlorotetrazolo[5,1-c]benzo[1,2,4]triazine. FEMS Yeast Res 12(8):958-68
Ha CW, et al.  (2012) Nsi1 plays a significant role in the silencing of ribosomal DNA in Saccharomyces cerevisiae. Nucleic Acids Res 40(11):4892-903
Haldar S, et al.  (2012) High copies of SUM1 enhance the stability of wild-type microtubules against adverse conditions in Saccharomyces cerevisiae. Biochem Biophys Res Commun 418(3):525-30
Lee SS, et al.  (2012) Whole lifespan microscopic observation of budding yeast aging through a microfluidic dissection platform. Proc Natl Acad Sci U S A 109(13):4916-20
Maicher A, et al.  (2012) Deregulated telomere transcription causes replication-dependent telomere shortening and promotes cellular senescence. Nucleic Acids Res 40(14):6649-59
Milliman EJ, et al.  (2012) Recruitment of rpd3 to the telomere depends on the protein arginine methyltransferase hmt1. PLoS One 7(8):e44656
Nagesh P, et al.  (2012) The SUMO E3 ligase Siz2 exerts a locus-dependent effect on gene silencing in Saccharomyces cerevisiae. Eukaryot Cell 11(4):452-62
Peng J and Zhou JQ  (2012) The tail-module of yeast Mediator complex is required for telomere heterochromatin maintenance. Nucleic Acids Res 40(2):581-93
Poon BP and Mekhail K  (2012) Effects of Perinuclear Chromosome Tethers in the Telomeric URA3/5FOA System Reflect Changes to Gene Silencing and not Nucleotide Metabolism. Front Genet 3():144
Richardson LA, et al.  (2012) A conserved deubiquitinating enzyme controls cell growth by regulating RNA polymerase I stability. Cell Rep 2(2):372-85
Sampaio-Marques B, et al.  (2012) SNCA (a-synuclein)-induced toxicity in yeast cells is dependent on sirtuin 2 (Sir2)-mediated mitophagy. Autophagy 8(10):1494-509
Sun K, et al.  (2012) Anti-aging effects of hesperidin on Saccharomyces cerevisiae via inhibition of reactive oxygen species and UTH1 gene expression. Biosci Biotechnol Biochem 76(4):640-5
Weiner A, et al.  (2012) Systematic dissection of roles for chromatin regulators in a yeast stress response. PLoS Biol 10(7):e1001369
Zill OA, et al.  (2012) Evolutionary analysis of heterochromatin protein compatibility by interspecies complementation in Saccharomyces. Genetics 192(3):1001-14
Alba Sorolla M, et al.  (2011) Sir2 is induced by oxidative stress in a yeast model of Huntington disease and its activation reduces protein aggregation. Arch Biochem Biophys 510(1):27-34
Caballero A, et al.  (2011) Absence of mitochondrial translation control proteins extends life span by activating sirtuin-dependent silencing. Mol Cell 42(3):390-400
Carmona-Gutierrez D, et al.  (2011) The propeptide of yeast cathepsin D inhibits programmed necrosis. Cell Death Dis 2():e161
Chan JN, et al.  (2011) Perinuclear Cohibin Complexes Maintain Replicative Life Span via Roles at Distinct Silent Chromatin Domains. Dev Cell 20(6):867-79
Chang JS and Winston F  (2011) Spt10 and Spt21 Are Required for Transcriptional Silencing in Saccharomyces cerevisiae. Eukaryot Cell 10(1):118-29
Delaney JR, et al.  (2011) Quantitative evidence for early life fitness defects from 32 longevity-associated alleles in yeast. Cell Cycle 10(1):156-65
Delaney JR, et al.  (2011) Sir2 deletion prevents lifespan extension in 32 long-lived mutants. Aging Cell 10(6):1089-91
Froyd CA and Rusche LN  (2011) The duplicated deacetylases Sir2 and Hst1 subfunctionalized by acquiring complementary inactivating mutations. Mol Cell Biol 31(16):3351-65
Houseley J and Tollervey D  (2011) Repeat expansion in the budding yeast ribosomal DNA can occur independently of the canonical homologous recombination machinery. Nucleic Acids Res 39(20):8778-91
Kruegel U, et al.  (2011) Elevated Proteasome Capacity Extends Replicative Lifespan in Saccharomyces cerevisiae. PLoS Genet 7(9):e1002253
Lam YT, et al.  (2011) Changes in reactive oxygen species begin early during replicative aging of Saccharomyces cerevisiae cells. Free Radic Biol Med 50(8):963-70
Laskar S, et al.  (2011) HSP90 Controls SIR2 Mediated Gene Silencing. PLoS One 6(8):e23406