SCS7/YMR272C Literature Guide Help

Other names published for SCS7: FAH1, fatty acid alpha-hydroxylase, YMR272C

SCS7 - Strains/Constructs (18)

ReferenceOther Genes Addressed
Tani M and Kuge O  (2012) Hydroxylation state of fatty acid and long-chain base moieties of sphingolipid determine the sensitivity to growth inhibition due to AUR1 repression in Saccharomyces cerevisiae. Biochem Biophys Res Commun 417(2):673-8
Tani M and Kuge O  (2012) Involvement of complex sphingolipids and phosphatidylserine in endosomal trafficking in yeast Saccharomyces cerevisiae. Mol Microbiol 86(5):1262-80
Kavun Ozbayraktar FB and Ulgen KO  (2011) Stoichiometric network reconstruction and analysis of yeast sphingolipid metabolism incorporating different states of hydroxylation. Biosystems 104(1):63-75
Dawaliby R and Mayer A  (2010) Microautophagy of the nucleus coincides with a vacuolar diffusion barrier at nuclear-vacuolar junctions. Mol Biol Cell 21(23):4173-83
Shakoury-Elizeh M, et al.  (2010) Metabolic response to iron deficiency in Saccharomyces cerevisiae. J Biol Chem 285(19):14823-33
Tani M and Kuge O  (2010) Requirement of a specific group of sphingolipid-metabolizing enzyme for growth of yeast Saccharomyces cerevisiae under impaired metabolism of glycerophospholipids. Mol Microbiol 78(2):395-413
Bosson R, et al.  (2009) Incorporation of ceramides into Saccharomyces cerevisiae glycosylphosphatidylinositol-anchored proteins can be monitored in vitro. Eukaryot Cell 8(3):306-14
Guan XL, et al.  (2009) Functional interactions between sphingolipids and sterols in biological membranes regulating cell physiology. Mol Biol Cell 20(7):2083-95
Gaigg B, et al.  (2005) Synthesis of sphingolipids with very long chain fatty acids but not ergosterol is required for routing of newly synthesized plasma membrane ATPase to the cell surface of yeast. J Biol Chem 280(23):22515-22
Zaremberg V, et al.  (2005) Cytotoxicity of an anti-cancer lysophospholipid through selective modification of lipid raft composition. J Biol Chem 280(45):38047-58
Parsons AB, et al.  (2004) Integration of chemical-genetic and genetic interaction data links bioactive compounds to cellular target pathways. Nat Biotechnol 22(1):62-9
Tong AH, et al.  (2004) Global mapping of the yeast genetic interaction network. Science 303(5659):808-13
Uemura S, et al.  (2003) Csg1p and newly identified Csh1p function in mannosylinositol phosphorylceramide synthesis by interacting with Csg2p. J Biol Chem 278(46):45049-55
Hama H, et al.  (2000) Requirement of sphingolipid alpha-hydroxylation for fungicidal action of syringomycin E. FEBS Lett 478(1-2):26-8
Dunn TM, et al.  (1998) Synthesis of monohydroxylated inositolphosphorylceramide (IPC-C) in Saccharomyces cerevisiae requires Scs7p, a protein with both a cytochrome b5-like domain and a hydroxylase/desaturase domain. Yeast 14(4):311-21
Haak D, et al.  (1997) Hydroxylation of Saccharomyces cerevisiae ceramides requires Sur2p and Scs7p. J Biol Chem 272(47):29704-10
Mitchell AG and Martin CE  (1997) Fah1p, a Saccharomyces cerevisiae cytochrome b5 fusion protein, and its Arabidopsis thaliana homolog that lacks the cytochrome b5 domain both function in the alpha-hydroxylation of sphingolipid-associated very long chain fatty acids. J Biol Chem 272(45):28281-8
Zhao C, et al.  (1994) Suppressors of the Ca(2+)-sensitive yeast mutant (csg2) identify genes involved in sphingolipid biosynthesis. Cloning and characterization of SCS1, a gene required for serine palmitoyltransferase activity. J Biol Chem 269(34):21480-8