PEX4/YGR133W Literature Guide Help

Other names published for PEX4: PAS2, UBC10, E2 ubiquitin-protein ligase peroxin 4, YGR133W

PEX4 - Strains/Constructs (29)

ReferenceOther Genes Addressed
Hensel A, et al.  (2011) Cysteine-dependent ubiquitination of Pex18p is linked to cargo translocation across the peroxisomal membrane. J Biol Chem 286(50):43495-505
Jung PP, et al.  (2011) Ploidy influences cellular responses to gross chromosomal rearrangements in Saccharomyces cerevisiae. BMC Genomics 12(1):331
Williams C, et al.  (2011) Insights into ubiquitin-conjugating enzyme/ co-activator interactions from the structure of the Pex4p:Pex22p complex. EMBO J 31(2):391-402
Haworth J, et al.  (2010) Ubc4 and Not4 Regulate Steady-State Levels of DNA Polymerase-{alpha} to Promote Efficient and Accurate DNA Replication. Mol Biol Cell 21(18):3205-19
Moravcevic K, et al.  (2010) Kinase associated-1 domains drive MARK/PAR1 kinases to membrane targets by binding acidic phospholipids. Cell 143(6):966-77
Saleem RA, et al.  (2010) Genome-wide analysis of effectors of peroxisome biogenesis.LID - e11953 [pii] PLoS One 5(8)
Platta HW, et al.  (2009) Pex2 and pex12 function as protein-ubiquitin ligases in peroxisomal protein import. Mol Cell Biol 29(20):5505-16
Teixeira MC, et al.  (2009) Genome-wide identification of Saccharomyces cerevisiae genes required for maximal tolerance to ethanol. Appl Environ Microbiol 75(18):5761-72
Loring GL, et al.  (2008) Yeast Chfr homologs retard cell cycle at G1 and G2/M via Ubc4 and Ubc13/Mms2-dependent ubiquitination. Cell Cycle 7(1):96-105
Williams C, et al.  (2008) Pex10p functions as an E3 ligase for the Ubc4p-dependent ubiquitination of Pex5p. Biochem Biophys Res Commun 374(4):620-4
Lockshon D, et al.  (2007) The sensitivity of yeast mutants to oleic Acid implicates the peroxisome and other processes in membrane function. Genetics 175(1):77-91
Rodrigo-Brenni MC and Morgan DO  (2007) Sequential E2s Drive Polyubiquitin Chain Assembly on APC Targets. Cell 130(1):127-39
Williams C, et al.  (2007) A conserved cysteine is essential for Pex4p-dependent ubiquitination of the peroxisomal import receptor Pex5p. J Biol Chem 282(31):22534-43
van der Klei I and Veenhuis M  (2007) Protein targeting to yeast peroxisomes. Methods Mol Biol 390:373-92
Hiraishi H, et al.  (2006) Enhancement of Stress Tolerance in Saccharomyces cerevisiae by Overexpression of Ubiquitin Ligase Rsp5 and Ubiquitin-Conjugating Enzymes. Biosci Biotechnol Biochem 70(11):2762-5
Rosenkranz K, et al.  (2006) Functional association of the AAA complex and the peroxisomal importomer. FEBS J 273(16):3804-15
Kiel JA, et al.  (2005) Ubiquitination of the peroxisomal targeting signal type 1 receptor, Pex5p, suggests the presence of a quality control mechanism during peroxisomal matrix protein import. J Biol Chem 280(3):1921-30
Kragt A, et al.  (2005) The Saccharomyces cerevisiae peroxisomal import receptor Pex5p is monoubiquitinated in wild type cells. J Biol Chem 280(9):7867-74
Platta HW, et al.  (2004) Ubiquitination of the peroxisomal import receptor Pex5p. Biochem J 384(Pt 1):37-45
Tong AH, et al.  (2004) Global mapping of the yeast genetic interaction network. Science 303(5659):808-13
Eckert JH and Johnsson N  (2003) Pex10p links the ubiquitin conjugating enzyme Pex4p to the protein import machinery of the peroxisome. J Cell Sci 116(Pt 17):3623-34
Wang Y, et al.  (2003) Regulation of Ste7 ubiquitination by Ste11 phosphorylation and the Skp1-Cullin-F-box complex. J Biol Chem 278(25):22284-9
Purdue PE and Lazarow PB  (2001) Pex18p is constitutively degraded during peroxisome biogenesis. J Biol Chem 276(50):47684-9
Hettema EH, et al.  (2000) Saccharomyces cerevisiae pex3p and pex19p are required for proper localization and stability of peroxisomal membrane proteins. EMBO J 19(2):223-33
Sears C, et al.  (1998) NF-kappa B p105 processing via the ubiquitin-proteasome pathway. J Biol Chem 273(3):1409-19
Erdmann R and Kunau WH  (1994) Purification and immunolocalization of the peroxisomal 3-oxoacyl-CoA thiolase from Saccharomyces cerevisiae. Yeast 10(9):1173-82
Van der Leij I, et al.  (1992) Isolation of peroxisome assembly mutants from Saccharomyces cerevisiae with different morphologies using a novel positive selection procedure. J Cell Biol 119(1):153-62
Wiebel FF and Kunau WH  (1992) The Pas2 protein essential for peroxisome biogenesis is related to ubiquitin-conjugating enzymes. Nature 359(6390):73-6
Erdmann R, et al.  (1989) Isolation of peroxisome-deficient mutants of Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 86(14):5419-23