LEM3/YNL323W Literature Guide Help

Other names published for LEM3: BRE3, ROS3, YNL323W

LEM3 - Strains/Constructs (28)

ReferenceOther Genes Addressed
Baldridge RD and Graham TR  (2012) Identification of residues defining phospholipid flippase substrate specificity of type IV P-type ATPases. Proc Natl Acad Sci U S A 109(6):E290-8
Das A, et al.  (2012) Flippase-mediated phospholipid asymmetry promotes fast Cdc42 recycling in dynamic maintenance of cell polarity.LID - 10.1038/ncb2444 [doi] Nat Cell Biol ()
Healey KR, et al.  (2012) CRS-MIS in Candida glabrata: sphingolipids modulate echinocandin-Fks interaction. Mol Microbiol 86(2):303-13
Bircham PW, et al.  (2011) Secretory pathway genes assessed by high-throughput microscopy and synthetic genetic array analysis. Mol Biosyst 7(9):2589-98
Chen R, et al.  (2011) Human TMEM30a Promotes Uptake of Antitumor and Bioactive Choline Phospholipids into Mammalian Cells. J Immunol 186(5):3215-25
Lanthaler K, et al.  (2011) Genome-wide assessment of the carriers involved in the cellular uptake of drugs: a model system in yeast. BMC Biol 9(1):70
Deng L, et al.  (2010) Incorporation and remodeling of phosphatidylethanolamine containing short acyl residues in yeast. Biochim Biophys Acta 1801(6):635-645
Lenoir G, et al.  (2009) Cdc50p plays a vital role in the ATPase reaction cycle of the putative aminophospholipid transporter drs2p. J Biol Chem 284(27):17956-67
Ono Y, et al.  (2009) Involvement of LEM3/ROS3 in the uptake of phosphatidylcholine with short acyl chains in Saccharomyces cerevisiae. Biosci Biotechnol Biochem 73(3):750-2
Rockwell NC, et al.  (2009) ABC transporter Pdr10 regulates the membrane microenvironment of Pdr12 in Saccharomyces cerevisiae. J Membr Biol 229(1):27-52
Ikeda M, et al.  (2008) The rim101 pathway is involved in rsb1 expression induced by altered lipid asymmetry. Mol Biol Cell 19(5):1922-31
Furuta N, et al.  (2007) Endocytic recycling in yeast is regulated by putative phospholipid translocases and the ypt31p/32p-rcy1p pathway. Mol Biol Cell 18(1):295-312
Riekhof WR, et al.  (2007) Lysophosphatidylcholine metabolism in Saccharomyces cerevisiae: the role of P-type ATPases in transport and a broad specificity acyltransferase in acylation. J Biol Chem 282(51):36853-61
Saito K, et al.  (2007) Transbilayer phospholipid flipping regulates Cdc42p signaling during polarized cell growth via Rga GTPase-activating proteins. Dev Cell 13(5):743-51
Noji T, et al.  (2006) Mutational analysis of the Lem3p-Dnf1p putative phospholipid-translocating P-type ATPase reveals novel regulatory roles for Lem3p and a carboxyl-terminal region of Dnf1p independent of the phospholipid-translocating activity of Dnf1p in yeast. Biochem Biophys Res Commun 344(1):323-31
Riekhof WR and Voelker DR  (2006) Uptake and utilization of lyso-phosphatidylethanolamine by Saccharomyces cerevisiae. J Biol Chem 281(48):36588-96
Elvington SM, et al.  (2005) Fluorescent, acyl chain-labeled phosphatidylcholine analogs reveal novel transport pathways across the plasma membrane of yeast. J Biol Chem 280(49):40957-64
Iwamoto K, et al.  (2004) Local exposure of phosphatidylethanolamine on the yeast plasma membrane is implicated in cell polarity. Genes Cells 9(10):891-903
Kihara A and Igarashi Y  (2004) Cross talk between sphingolipids and glycerophospholipids in the establishment of plasma membrane asymmetry. Mol Biol Cell 15(11):4949-59
Saito K, et al.  (2004) Cdc50p, a protein required for polarized growth, associates with the Drs2p P-type ATPase implicated in phospholipid translocation in Saccharomyces cerevisiae. Mol Biol Cell 15(7):3418-32
Hanson PK, et al.  (2003) Lem3p is essential for the uptake and potency of alkylphosphocholine drugs, edelfosine and miltefosine. J Biol Chem 278(38):36041-50
Huang D, et al.  (2002) Dissection of a complex phenotype by functional genomics reveals roles for the yeast cyclin-dependent protein kinase Pho85 in stress adaptation and cell integrity. Mol Cell Biol 22(14):5076-88
Kato U, et al.  (2002) A novel membrane protein, Ros3p, is required for phospholipid translocation across the plasma membrane in Saccharomyces cerevisiae. J Biol Chem 277(40):37855-62
Muren E, et al.  (2001) Identification of yeast deletion strains that are hypersensitive to brefeldin A or monensin, two drugs that affect intracellular transport. Yeast 18(2):163-72
Radji M, et al.  (2001) The cloning and characterization of the CDC50 gene family in Saccharomyces cerevisiae. Yeast 18(3):195-205
de Groot PW, et al.  (2001) A genomic approach for the identification and classification of genes involved in cell wall formation and its regulation in Saccharomyces cerevisiae. Comp Funct Genomics 2(3):124-42
Sitcheran R, et al.  (2000) A genetic analysis of glucocorticoid receptor signaling. Identification and characterization of ligand-effect modulators in Saccharomyces cerevisiae. Genetics 156(3):963-72
Maftahi M, et al.  (1998) Generation of Saccharomyces cerevisiae deletants and basic phenotypic analysis of eight novel genes from the left arm of chromosome XIV. Yeast 14(3):271-80