LAC1/YKL008C Literature Guide Help

Other names published for LAC1: DGT1, sphingosine N-acyltransferase LAC1, YKL008C

LAC1 - Strains/Constructs (16)

ReferenceOther Genes Addressed
Cheon SA, et al.  (2012) Distinct roles of two ceramide synthases, CaLag1p and CaLac1p, in the morphogenesis of Candida albicans. Mol Microbiol 83(4):728-45
Montefusco DJ, et al.  (2012) Sphingoid bases and the serine catabolic enzyme CHA1 define a novel feedforward/feedback mechanism in the response to serine availability. J Biol Chem 287(12):9280-9
Kavun Ozbayraktar FB and Ulgen KO  (2011) Stoichiometric network reconstruction and analysis of yeast sphingolipid metabolism incorporating different states of hydroxylation. Biosystems 104(1):63-75
Lee YJ, et al.  (2011) Defects in very long chain Fatty Acid synthesis enhance alpha-synuclein toxicity in a yeast model of Parkinson's disease. PLoS One 6(1):e15946
Kim SK, et al.  (2010) Effect of Expression of Genes in the Sphingolipid Synthesis Pathway on the Biosynthesis of Ceramide in Saccharomyces cerevisiae. J Microbiol Biotechnol 20(2):356-60
Cerantola V, et al.  (2009) Aureobasidin A arrests growth of yeast cells through both ceramide intoxication and deprivation of essential inositolphosphorylceramides. Mol Microbiol 71(6):1523-37
Cerantola V, et al.  (2007) Yeast sphingolipids do not need to contain very long chain fatty acids. Biochem J 401(1):205-216
Kageyama-Yahara N and Riezman H  (2006) Transmembrane topology of ceramide synthase in yeast. Biochem J 398(3):585-93
Meier KD, et al.  (2006) Sphingoid base is required for translation initiation during heat stress in Saccharomyces cerevisiae. Mol Biol Cell 17(3):1164-75
Gaigg B, et al.  (2005) Synthesis of sphingolipids with very long chain fatty acids but not ergosterol is required for routing of newly synthesized plasma membrane ATPase to the cell surface of yeast. J Biol Chem 280(23):22515-22
Vallee B and Riezman H  (2005) Lip1p: a novel subunit of acyl-CoA ceramide synthase. EMBO J 24(4):730-41
Kolaczkowski M, et al.  (2004) Differential regulation of ceramide synthase components LAC1 and LAG1 in Saccharomyces cerevisiae. Eukaryot Cell 3(4):880-92
Guillas I, et al.  (2003) Human homologues of LAG1 reconstitute Acyl-CoA-dependent ceramide synthesis in yeast. J Biol Chem 278(39):37083-91
Guillas I, et al.  (2001) C26-CoA-dependent ceramide synthesis of Saccharomyces cerevisiae is operated by Lag1p and Lac1p. EMBO J 20(11):2655-65
Schorling S, et al.  (2001) Lag1p and Lac1p are essential for the Acyl-CoA-dependent ceramide synthase reaction in Saccharomyces cerevisae. Mol Biol Cell 12(11):3417-27
Jiang JC, et al.  (1998) Homologs of the yeast longevity gene LAG1 in Caenorhabditis elegans and human. Genome Res 8(12):1259-72