GCN3/YKR026C Literature Guide Help

Other names published for GCN3: AAS2, YKR026C

GCN3 - Strains/Constructs (39)

Results: 1 - 30 of 39 records
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ReferenceOther Genes Addressed
Elsby R, et al.  (2011) The alpha subunit of eukaryotic initiation factor 2B (eIF2B) is required for eIF2-mediated translational suppression of vesicular stomatitis virus. J Virol 85(19):9716-25
Gresham D, et al.  (2011) System-Level Analysis of Genes and Functions Affecting Survival During Nutrient Starvation in Saccharomyces cerevisiae. Genetics 187(1):299-317
Iglesias-Gato D, et al.  (2011) Guanine Nucleotide Pool Imbalance Impairs Multiple Steps of Protein Synthesis and Disrupts GCN4 Translational Control in Saccharomyces cerevisiae. Genetics 187(1):105-22
Dev K, et al.  (2010) The beta/Gcd7 subunit of eukaryotic translation initiation factor 2B (eIF2B), a guanine nucleotide exchange factor, is crucial for binding eIF2 in vivo. Mol Cell Biol 30(21):5218-33
Taylor EJ, et al.  (2010) Fusel alcohols regulate translation initiation by inhibiting eIF2B to reduce ternary complex in a mechanism that may involve altering the integrity and dynamics of the eIF2B body. Mol Biol Cell 21(13):2202-16
Dev K, et al.  (2009) Archaeal aIF2B interacts with eukaryotic translation initiation factors eIF2alpha and eIF2Balpha: Implications for aIF2B function and eIF2B regulation. J Mol Biol 392(3):701-22
Kito K, et al.  (2007) A Synthetic Protein Approach toward Accurate Mass Spectrometric Quantification of Component Stoichiometry of Multiprotein Complexes. J Proteome Res 6(2):792-800
Martin-Marcos P, et al.  (2007) Ribosomal protein L33 is required for ribosome biogenesis, subunit joining, and repression of GCN4 translation. Mol Cell Biol 27(17):5968-85
Menacho-Marquez M, et al.  (2007) Gcn2p regulates a G1/S cell cycle checkpoint in response to DNA damage. Cell Cycle 6(18):2302-5
Dey M, et al.  (2005) PKR and GCN2 kinases and guanine nucleotide exchange factor eukaryotic translation initiation factor 2B (eIF2B) recognize overlapping surfaces on eIF2alpha. Mol Cell Biol 25(8):3063-75
Richardson JP, et al.  (2004) Mutations causing childhood ataxia with central nervous system hypomyelination reduce eukaryotic initiation factor 2B complex formation and activity. Mol Cell Biol 24(6):2352-63
Rodriguez-Hernandez CJ, et al.  (2003) The immunosuppressant FK506 uncovers a positive regulatory cross-talk between the Hog1p and Gcn2p pathways. J Biol Chem 278(36):33887-95
Goossens A, et al.  (2001) The protein kinase Gcn2p mediates sodium toxicity in yeast. J Biol Chem 276(33):30753-60
Pavitt GD, et al.  (1998) eIF2 independently binds two distinct eIF2B subcomplexes that catalyze and regulate guanine-nucleotide exchange. Genes Dev 12(4):514-26
Pavitt GD, et al.  (1997) Homologous segments in three subunits of the guanine nucleotide exchange factor eIF2B mediate translational regulation by phosphorylation of eIF2. Mol Cell Biol 17(3):1298-313
Yang W and Hinnebusch AG  (1996) Identification of a regulatory subcomplex in the guanine nucleotide exchange factor eIF2B that mediates inhibition by phosphorylated eIF2. Mol Cell Biol 16(11):6603-16
Dever TE, et al.  (1995) Modulation of tRNA(iMet), eIF-2, and eIF-2B expression shows that GCN4 translation is inversely coupled to the level of eIF-2.GTP.Met-tRNA(iMet) ternary complexes. Mol Cell Biol 15(11):6351-63
Flowers KM, et al.  (1995) Molecular cloning and characterization of cDNA encoding the alpha subunit of the rat protein synthesis initiation factor eIF-2B. Proc Natl Acad Sci U S A 92(10):4274-8
Feng L, et al.  (1994) Casein kinase II mediates multiple phosphorylation of Saccharomyces cerevisiae eIF-2 alpha (encoded by SUI2), which is required for optimal eIF-2 function in S. cerevisiae. Mol Cell Biol 14(8):5139-53
Bushman JL, et al.  (1993) Guanine nucleotide exchange factor for eukaryotic translation initiation factor 2 in Saccharomyces cerevisiae: interactions between the essential subunits GCD2, GCD6, and GCD7 and the regulatory subunit GCN3. Mol Cell Biol 13(8):4618-31
Dever TE, et al.  (1993) Mammalian eukaryotic initiation factor 2 alpha kinases functionally substitute for GCN2 protein kinase in the GCN4 translational control mechanism of yeast. Proc Natl Acad Sci U S A 90(10):4616-20
Vazquez de Aldana CR, et al.  (1993) Mutations in the alpha subunit of eukaryotic translation initiation factor 2 (eIF-2 alpha) that overcome the inhibitory effect of eIF-2 alpha phosphorylation on translation initiation. Proc Natl Acad Sci U S A 90(15):7215-9
Ramirez M, et al.  (1992) Mutations activating the yeast eIF-2 alpha kinase GCN2: isolation of alleles altering the domain related to histidyl-tRNA synthetases. Mol Cell Biol 12(12):5801-15
Foiani M, et al.  (1991) GCD2, a translational repressor of the GCN4 gene, has a general function in the initiation of protein synthesis in Saccharomyces cerevisiae. Mol Cell Biol 11(6):3203-16
Hannig EM, et al.  (1990) The translational activator GCN3 functions downstream from GCN1 and GCN2 in the regulatory pathway that couples GCN4 expression to amino acid availability in Saccharomyces cerevisiae. Genetics 126(3):549-62
Messenguy F and Scherens B  (1990) Induction of "General Control" and thermotolerance in cdc mutants of Saccharomyces cerevisiae. Mol Gen Genet 224(2):257-63
Paddon CJ and Hinnebusch AG  (1989) gcd12 mutations are gcn3-dependent alleles of GCD2, a negative regulator of GCN4 in the general amino acid control of Saccharomyces cerevisiae. Genetics 122(3):543-50
Williams NP, et al.  (1989) Mutations in the structural genes for eukaryotic initiation factors 2 alpha and 2 beta of Saccharomyces cerevisiae disrupt translational control of GCN4 mRNA. Proc Natl Acad Sci U S A 86(19):7515-9
Hannig EM and Hinnebusch AG  (1988) Molecular analysis of GCN3, a translational activator of GCN4: evidence for posttranslational control of GCN3 regulatory function. Mol Cell Biol 8(11):4808-20
Harashima S, et al.  (1987) Interactions between positive and negative regulators of GCN4 controlling gene expression and entry into the yeast cell cycle. Genetics 117(3):409-19
Results: 1 - 30 of 39 records
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