GCN2/YDR283C Literature Guide Help

Other names published for GCN2: AAS1, NDR2, AAS102, YDR283C

GCN2 - Strains/Constructs (97)

ReferenceOther Genes Addressed
Cap M, et al.  (2012) Cell differentiation within a yeast colony: metabolic and regulatory parallels with a tumor-affected organism. Mol Cell 46(4):436-48
Hueso G, et al.  (2012) A novel role for protein kinase Gcn2 in yeast tolerance to intracellular acid stress. Biochem J 441(1):255-64
Reid PJ, et al.  (2012) Identification of intersubunit domain interactions within eukaryotic initiation factor (eIF) 2B, the nucleotide exchange factor for translation initiation. J Biol Chem 287(11):8275-85
Rodriguez-Hernandez CJ, et al.  (2012) Anti-diabetic and anti-obesity agent sodium tungstate enhances GCN pathway activation through Glc7p inhibition. FEBS Lett 586(3):270-6
Visweswaraiah J, et al.  (2012) Overexpression of eukaryotic translation elongation factor 3 impairs Gcn2 protein activation. J Biol Chem 287(45):37757-68
Alabrudzinska M, et al.  (2011) Dipoid-Specific Genome Stability Genes of S. cerevisiae: Genomic Screen Reveals Haploidization as an Escape from Persisting DNA Rearrangement Stress. PLoS One 6(6):e21124
Elsby R, et al.  (2011) The alpha subunit of eukaryotic initiation factor 2B (eIF2B) is required for eIF2-mediated translational suppression of vesicular stomatitis virus. J Virol 85(19):9716-25
Franzosa EA, et al.  (2011) Heterozygous yeast deletion collection screens reveal essential targets of hsp90. PLoS One 6(11):e28211
Iglesias-Gato D, et al.  (2011) Guanine Nucleotide Pool Imbalance Impairs Multiple Steps of Protein Synthesis and Disrupts GCN4 Translational Control in Saccharomyces cerevisiae. Genetics 187(1):105-22
Kato K, et al.  (2011) Severe ethanol stress induces assembly of stress granules in Saccharomyces cerevisiae. Yeast 28(5):339-47
Molin M, et al.  (2011) Life Span Extension and H(2)O(2) Resistance Elicited by Caloric Restriction Require the Peroxiredoxin Tsa1 in Saccharomyces cerevisiae. Mol Cell 43(5):823-33
Uluisik I, et al.  (2011) Boron stress activates the general amino acid control mechanism and inhibits protein synthesis. PLoS One 6(11):e27772
Zhang F and Hinnebusch AG  (2011) An upstream ORF with non-AUG start codon is translated in vivo but dispensable for translational control of GCN4 mRNA. Nucleic Acids Res 39(8):3128-40
Cherkasova V, et al.  (2010) Snf1 promotes phosphorylation of the alpha subunit of eukaryotic translation initiation factor 2 by activating Gcn2 and inhibiting phosphatases Glc7 and Sit4. Mol Cell Biol 30(12):2862-73
Ecker N, et al.  (2010) Induction of autophagic flux by amino acid deprivation is distinct from nitrogen starvation-induced macroautophagy. Autophagy 6(7):879-90
Elantak L, et al.  (2010) The Indispensable N-Terminal Half of eIF3j/HCR1 Cooperates with its Structurally Conserved Binding Partner eIF3b/PRT1-RRM and with eIF1A in Stringent AUG Selection. J Mol Biol 396(4):1097-1116
Kilchert C, et al.  (2010) Defects in the Secretory Pathway and High Ca2+ Induce Multiple P-bodies. Mol Biol Cell 21(15):2624-38
Lin CA, et al.  (2010) The sua5 protein is essential for normal translational regulation in yeast. Mol Cell Biol 30(1):354-63
Moravcevic K, et al.  (2010) Kinase associated-1 domains drive MARK/PAR1 kinases to membrane targets by binding acidic phospholipids. Cell 143(6):966-77
Nomura W, et al.  (2010) Methylglyoxal activates Gcn2 to phosphorylate eIF2alpha independently of the TOR pathway in Saccharomyces cerevisiae. Appl Microbiol Biotechnol 86(6):1887-94
Rivera-Ruiz ME, et al.  (2010) Post-transcriptional regulation in the myo1Delta mutant of Saccharomyces cerevisiae. BMC Genomics 11():690
Zaborske JM, et al.  (2010) Selective control of amino acid metabolism by the GCN2 eIF2 kinase pathway in Saccharomyces cerevisiae. BMC Biochem 11():29
Zhang K, et al.  (2010) Unrestrictive identification of non-phosphorylation PTMs in yeast kinases by MS and PTMap. Proteomics 10(5):896-903
Almeida B, et al.  (2009) Yeast protein expression profile during acetic acid-induced apoptosis indicates causal involvement of the TOR pathway. Proteomics 9(3):720-32
Deplazes A, et al.  (2009) Yeast Uri1p promotes translation initiation and may provide a link to cotranslational quality control. EMBO J 28(10):1429-41
Garriz A, et al.  (2009) A network of hydrophobic residues impeding helix alphaC rotation maintains latency of kinase Gcn2, which phosphorylates the alpha subunit of translation initiation factor 2. Mol Cell Biol 29(6):1592-607
Motlekar N, et al.  (2009) Discovery of Chemical Modulators of a Conserved Translational Control Pathway by Parallel Screening in Yeast. Assay Drug Dev Technol 7(5):479-494
Tsoi BM, et al.  (2009) Essential Role of One-carbon Metabolism and Gcn4p and Bas1p Transcriptional Regulators during Adaptation to Anaerobic Growth of Saccharomyces cerevisiae. J Biol Chem 284(17):11205-15
Wout PK, et al.  (2009) Saccharomyces cerevisiae Rbg1 protein and its binding partner Gir2 interact on Polyribosomes with Gcn1. Eukaryot Cell 8(7):1061-71
Zaborske JM, et al.  (2009) Genome-wide Analysis of tRNA Charging and Activation of the eIF2 Kinase Gcn2p. J Biol Chem 284(37):25254-67