DRS2/YAL026C Literature Guide Help

Other names published for DRS2: FUN38, SWA3, aminophospholipid-translocating P4-type ATPase DRS2, YAL026C

DRS2 - Strains/Constructs (42)

ReferenceOther Genes Addressed
Baldridge RD and Graham TR  (2012) Identification of residues defining phospholipid flippase substrate specificity of type IV P-type ATPases. Proc Natl Acad Sci U S A 109(6):E290-8
Jacquot A, et al.  (2012) Phosphatidylserine stimulation of Drs2p?Cdc50p lipid translocase dephosphorylation is controlled by phosphatidylinositol-4-phosphate. J Biol Chem 287(16):13249-61
Stone A, et al.  (2012) Biochemical characterization of P4-ATPase mutations identified in patients with progressive familial intrahepatic cholestasis. J Biol Chem 287(49):41139-51
Brett CL, et al.  (2011) Genome-Wide Analysis Reveals the Vacuolar pH-Stat of Saccharomyces cerevisiae. PLoS One 6(3):e17619
Spitzer M, et al.  (2011) Cross-species discovery of syncretic drug combinations that potentiate the antifungal fluconazole. Mol Syst Biol 7():499
Banuelos MG, et al.  (2010) Genomic analysis of severe hypersensitivity to hygromycin B reveals linkage to vacuolar defects and new vacuolar gene functions in Saccharomyces cerevisiae. Curr Genet 56(2):121-37
Berthelet S, et al.  (2010) Functional Genomics Analysis of the Saccharomyces cerevisiae Iron Responsive Transcription Factor Aft1 Reveals Iron-Independent Functions. Genetics 185(3):1111-28
Guo Y, et al.  (2010) Phosphatidylserine Is Involved in the Ferrichrome-induced Plasma Membrane Trafficking of Arn1 in Saccharomyces cerevisiae. J Biol Chem 285(50):39564-73
Puts CF, et al.  (2010) A P(4)-ATPase Protein Interaction Network Reveals a Link between Aminophospholipid Transport and Phosphoinositide Metabolism. J Proteome Res 9(2):833-42
Lenoir G, et al.  (2009) Cdc50p plays a vital role in the ATPase reaction cycle of the putative aminophospholipid transporter drs2p. J Biol Chem 284(27):17956-67
Muthusamy BP, et al.  (2009) Control of protein and sterol trafficking by antagonistic activities of a type IV P-type ATPase and oxysterol binding protein homologue. Mol Biol Cell 20(12):2920-31
Natarajan P, et al.  (2009) Regulation of a Golgi flippase by phosphoinositides and an ArfGEF. Nat Cell Biol 11(12):1421-6
Zhou X and Graham TR  (2009) Reconstitution of phospholipid translocase activity with purified Drs2p, a type-IV P-type ATPase from budding yeast. Proc Natl Acad Sci U S A 106(39):16586-91
Abe F and Minegishi H  (2008) Global screening of genes essential for growth in high-pressure and cold environments: searching for basic adaptive strategies using a yeast deletion library. Genetics 178(2):851-72
Alamgir M, et al.  (2008) Chemical-genetic profile analysis in yeast suggests that a previously uncharacterized open reading frame, YBR261C, affects protein synthesis. BMC Genomics 9:583
Fei W, et al.  (2008) Genome-wide analysis of sterol-lipid storage and trafficking in Saccharomyces cerevisiae. Eukaryot Cell 7(2):401-14
Liu K, et al.  (2008) P4-ATPase Requirement for AP-1/Clathrin Function in Protein Transport from the trans-Golgi Network and Early Endosomes. Mol Biol Cell 19(8):3526-35
Ruotolo R, et al.  (2008) Membrane transporters and protein traffic networks differentially affecting metal tolerance: a genomic phenotyping study in yeast. Genome Biol 9(4):R67
Stevens HC, et al.  (2008) The Putative Aminophospholipid Translocases, DNF1 and DNF2, Are Not Required for 7-Nitrobenz-2-oxa-1,3-diazol-4-yl-phosphatidylserine Flip across the Plasma Membrane of Saccharomyces cerevisiae. J Biol Chem 283(50):35060-9
Takeuchi M, et al.  (2008) Saccharomyces cerevisiae Rot1 Is an Essential Molecular Chaperone in the Endoplasmic Reticulum. Mol Biol Cell 19(8):3514-25
Furuta N, et al.  (2007) Endocytic recycling in yeast is regulated by putative phospholipid translocases and the ypt31p/32p-rcy1p pathway. Mol Biol Cell 18(1):295-312
Alder-Baerens N, et al.  (2006) Loss of P4 ATPases Drs2p and Dnf3p disrupts aminophospholipid transport and asymmetry in yeast post-Golgi secretory vesicles. Mol Biol Cell 17(4):1632-42
Reiner S, et al.  (2006) A genomewide screen reveals a role of mitochondria in anaerobic uptake of sterols in yeast. Mol Biol Cell 17(1):90-103
Berger AC, et al.  (2005) A yeast model system for functional analysis of the Niemann-Pick type C protein 1 homolog, Ncr1p. Traffic 6(10):907-17
Kishimoto T, et al.  (2005) Defects in structural integrity of ergosterol and the Cdc50p-Drs2p putative phospholipid translocase cause accumulation of endocytic membranes, onto which actin patches are assembled in yeast. Mol Biol Cell 16(12):5592-609
Lee W, et al.  (2005) Genome-wide requirements for resistance to functionally distinct DNA-damaging agents. PLoS Genet 1(2):e24
Sciorra VA, et al.  (2005) Synthetic genetic array analysis of the PtdIns 4-kinase Pik1p identifies components in a Golgi-specific Ypt31/rab-GTPase signaling pathway. Mol Biol Cell 16(2):776-93
Chantalat S, et al.  (2004) The Arf activator Gea2p and the P-type ATPase Drs2p interact at the Golgi in Saccharomyces cerevisiae. J Cell Sci 117(Pt 5):711-22
Natarajan P, et al.  (2004) Drs2p-coupled aminophospholipid translocase activity in yeast Golgi membranes and relationship to in vivo function. Proc Natl Acad Sci U S A 101(29):10614-9
Parsons AB, et al.  (2004) Integration of chemical-genetic and genetic interaction data links bioactive compounds to cellular target pathways. Nat Biotechnol 22(1):62-9