CYS4/YGR155W Literature Guide Help

Other names published for CYS4: NHS5, STR4, VMA41, cystathionine beta-synthase CYS4, YGR155W

CYS4 - Strains/Constructs (36)

ReferenceOther Genes Addressed
Harsch MJ and Gardner RC  (2013) Yeast genes involved in sulfur and nitrogen metabolism affect the production of volatile thiols from Sauvignon Blanc musts. Appl Microbiol Biotechnol 97(1):223-35
Mayfield JA, et al.  (2012) Surrogate genetics and metabolic profiling for characterization of human disease alleles. Genetics 190(4):1309-23
Gresham D, et al.  (2011) System-Level Analysis of Genes and Functions Affecting Survival During Nutrient Starvation in Saccharomyces cerevisiae. Genetics 187(1):299-317
Jung PP, et al.  (2011) Ploidy influences cellular responses to gross chromosomal rearrangements in Saccharomyces cerevisiae. BMC Genomics 12(1):331
Kumar A, et al.  (2011) Converging evidence of mitochondrial dysfunction in a yeast model of homocysteine metabolism imbalance. J Biol Chem 286(24):21779-95
Suzuki T, et al.  (2011) Identification and characterization of genes involved in glutathione production in yeast. J Biosci Bioeng 112(2):107-13
Yadav V, et al.  (2011) Chlorophenol stress affects aromatic amino acid biosynthesis-a genome-wide study. Yeast 28(1):81-91
Yoshida S, et al.  (2011) A novel mechanism regulates H(2) S and SO(2) production in Saccharomyces cerevisiae. Yeast 28(2):109-21
Blank HM, et al.  (2009) Sulfur metabolism actively promotes initiation of cell division in yeast. PLoS One 4(11):e8018
Kim HS, et al.  (2009) Dissecting the pleiotropic consequences of a quantitative trait nucleotide. FEMS Yeast Res 9(5):713-22
Lodha PH, et al.  (2009) Investigation of residues Lys112, Glu136, His138, Gly247, Tyr248, and Asp249 in the active site of yeast cystathionine beta-synthase. Biochem Cell Biol 87(3):531-40
Narayanaswamy R, et al.  (2009) Widespread reorganization of metabolic enzymes into reversible assemblies upon nutrient starvation. Proc Natl Acad Sci U S A 106(25):10147-52
Singh LR and Kruger WD  (2009) Functional Rescue of Mutant Human Cystathionine {beta}-Synthase by Manipulation of Hsp26 and Hsp70 Levels in Saccharomyces cerevisiae. J Biol Chem 284(7):4238-45
Tsoi BM, et al.  (2009) Essential Role of One-carbon Metabolism and Gcn4p and Bas1p Transcriptional Regulators during Adaptation to Anaerobic Growth of Saccharomyces cerevisiae. J Biol Chem 284(17):11205-15
Linderholm AL, et al.  (2008) Identification of genes affecting hydrogen sulfide formation in Saccharomyces cerevisiae. Appl Environ Microbiol 74(5):1418-27
Ruotolo R, et al.  (2008) Membrane transporters and protein traffic networks differentially affecting metal tolerance: a genomic phenotyping study in yeast. Genome Biol 9(4):R67
Serero A, et al.  (2008) Yeast genes involved in cadmium tolerance: Identification of DNA replication as a target of cadmium toxicity. DNA Repair (Amst) 7(8):1262-75
Kumar A, et al.  (2006) Homocysteine- and cysteine-mediated growth defect is not associated with induction of oxidative stress response genes in yeast. Biochem J 396(1):61-9
Menant A, et al.  (2006) Determinants of the ubiquitin-mediated degradation of the Met4 transcription factor. J Biol Chem 281(17):11744-54
Sambade M, et al.  (2005) A genomic screen for yeast vacuolar membrane ATPase mutants. Genetics 170(4):1539-51
Srikanth CV, et al.  (2005) Multiple cis-regulatory elements and the yeast sulphur regulatory network are required for the regulation of the yeast glutathione transporter, Hgt1p. Curr Genet 47(6):345-58
Aitken SM and Kirsch JF  (2004) Role of active-site residues Thr81, Ser82, Thr85, Gln157, and Tyr158 in yeast cystathionine beta-synthase catalysis and reaction specificity. Biochemistry 43(7):1963-71
Chan SY and Appling DR  (2003) Regulation of S-adenosylmethionine levels in Saccharomyces cerevisiae. J Biol Chem 278(44):43051-9
Brenner C  (2000) A cultivated taste for yeast. Genome Biol 1(1):REVIEWS103
Hansen J and Johannesen PF  (2000) Cysteine is essential for transcriptional regulation of the sulfur assimilation genes in Saccharomyces cerevisiae. Mol Gen Genet 263(3):535-42
Jhee KH, et al.  (2000) Domain architecture of the heme-independent yeast cystathionine beta-synthase provides insights into mechanisms of catalysis and regulation. Biochemistry 39(34):10548-56
Jhee KH, et al.  (2000) Yeast cystathionine beta-synthase is a pyridoxal phosphate enzyme but, unlike the human enzyme, is not a heme protein. J Biol Chem 275(16):11541-4
Patton EE, et al.  (2000) SCF(Met30)-mediated control of the transcriptional activator Met4 is required for the G(1)-S transition. EMBO J 19(7):1613-24
Ono BI, et al.  (1999) Cysteine biosynthesis in Saccharomyces cerevisiae: a new outlook on pathway and regulation. Yeast 15(13):1365-75
Oluwatosin YE and Kane PM  (1998) Mutations in the yeast KEX2 gene cause a Vma(-)-like phenotype: a possible role for the Kex2 endoprotease in vacuolar acidification. Mol Cell Biol 18(3):1534-43