Other names published for MCM4: HCD21, CDC54, YPR019W
MCM4 LITERATURE TOPICS
- Curated Literature
- Genetics/Cell Biology
- Nucleic Acid Information
- Gene Product Information
- Related Genes/Proteins
- Research Aids
- Strains/Constructs
- Techniques and Reagents
- Genome-wide Analysis
- Proteome-wide Analysis
- Other Topics
- Additional Information
MCM4 - Strains/Constructs (39)
| Reference | Other Genes Addressed |
|---|---|
| Knott SR, et al. (2012) Forkhead Transcription Factors Establish Origin Timing and Long-Range Clustering in S. cerevisiae. Cell 148(1-2):99-111 | |
| Zhang Y, et al. (2012) Genome-wide screen identifies pathways that govern GAA/TTC repeat fragility and expansions in dividing and nondividing yeast cells. Mol Cell 48(2):254-65 | |
| Hombauer H, et al. (2011) Visualization of eukaryotic DNA mismatch repair reveals distinct recognition and repair intermediates. Cell 147(5):1040-53 | |
| Li XC and Tye BK (2011) Ploidy Dictates Repair Pathway Choice under DNA Replication Stress. Genetics 187(4):1031-40 | |
| Mantiero D, et al. (2011) Limiting replication initiation factors execute the temporal programme of origin firing in budding yeast.LID - 10.1038/emboj.2011.404 [doi] EMBO J () | |
| Takara TJ and Bell SP (2011) Multiple Cdt1 molecules act at each origin to load replication-competent Mcm2-7 helicases. EMBO J 30(24):4885-96 | |
| Bochman ML and Schwacha A (2010) The Saccharomyces cerevisiae Mcm6/2 and Mcm5/3 ATPase active sites contribute to the function of the putative Mcm2-7 'gate'. Nucleic Acids Res 38(18):6078-88 | |
| Lydeard JR, et al. (2010) Break-induced replication requires all essential DNA replication factors except those specific for pre-RC assembly. Genes Dev 24(11):1133-44 | |
| Ma L, et al. (2010) Identification of novel factors involved in or regulating initiation of DNA replication by a genome-wide phenotypic screen in Saccharomyces cerevisiae. Cell Cycle 9(21):4399-410 | |
| Ma X, et al. (2010) The effects of oligomerization on Saccharomyces cerevisiae Mcm4/6/7 function. BMC Biochem 11():37 | |
| Randell JC, et al. (2010) Mec1 is one of multiple kinases that prime the Mcm2-7 helicase for phosphorylation by Cdc7. Mol Cell 40(3):353-63 | |
| Sheu YJ and Stillman B (2010) The Dbf4-Cdc7 kinase promotes S phase by alleviating an inhibitory activity in Mcm4. Nature 463(7277):113-7 | |
| Zhai Y, et al. (2010) Cdc14p resets the competency of replication licensing by dephosphorylating multiple initiation proteins during mitotic exit in budding yeast. J Cell Sci 123(Pt 22):3933-43 | |
| Gambus A, et al. (2009) A key role for Ctf4 in coupling the MCM2-7 helicase to DNA polymerase alpha within the eukaryotic replisome. EMBO J 28(19):2992-3004 | |
| Li XC, et al. (2009) Aneuploidy and improved growth are coincident but not causal in a yeast cancer model. PLoS Biol 7(7):e1000161 | |
| Nishimura K, et al. (2009) An auxin-based degron system for the rapid depletion of proteins in nonplant cells. Nat Methods 6(12):917-22 | |
| Remus D, et al. (2009) Concerted loading of Mcm2-7 double hexamers around DNA during DNA replication origin licensing. Cell 139(4):719-30 | |
| Stead BE, et al. (2009) ATP binding and hydrolysis by Mcm2 regulate DNA binding by Mcm complexes. J Mol Biol 391(2):301-13 | |
| Steere NA, et al. (2009) Functional screen of human MCM2-7 variant alleles for disease-causing potential. Mutat Res 666(1-2):74-8 | |
| Bochman ML and Schwacha A (2007) Differences in the single-stranded DNA binding activities of MCM2-7 and MCM467: MCM2 and MCM5 define a slow ATP-dependent step. J Biol Chem 282(46):33795-804 | |
| Braun KA and Breeden LL (2007) Nascent transcription of MCM2-7 is important for nuclear localization of the minichromosome maintenance complex in G1. Mol Biol Cell 18(4):1447-56 | |
| Kanemaki M and Labib K (2006) Distinct roles for Sld3 and GINS during establishment and progression of eukaryotic DNA replication forks. EMBO J 25(8):1753-63 | |
| Sheu YJ and Stillman B (2006) Cdc7-Dbf4 phosphorylates MCM proteins via a docking site-mediated mechanism to promote S phase progression. Mol Cell 24(1):101-13 | |
| Yu L, et al. (2006) A survey of essential gene function in the yeast cell division cycle. Mol Biol Cell 17(11):4736-47 | |
| Calzada A, et al. (2005) Molecular anatomy and regulation of a stable replisome at a paused eukaryotic DNA replication fork. Genes Dev 19(16):1905-19 | |
| Davierwala AP, et al. (2005) The synthetic genetic interaction spectrum of essential genes. Nat Genet 37(10):1147-52 | |
| Liku ME, et al. (2005) CDK phosphorylation of a novel NLS-NES module distributed between two subunits of the Mcm2-7 complex prevents chromosomal rereplication. Mol Biol Cell 16(10):5026-39 | |
| Dasgupta A, et al. (2004) Sir Antagonist 1 (San1) is a ubiquitin ligase. J Biol Chem 279(26):26830-8 | |
| Ricke RM and Bielinsky AK (2004) Mcm10 regulates the stability and chromatin association of DNA polymerase-alpha. Mol Cell 16(2):173-85 | |
| Kaplan DL, et al. (2003) Mcm4,6,7 uses a "pump in ring" mechanism to unwind DNA by steric exclusion and actively translocate along a duplex. J Biol Chem 278(49):49171-82 |





