Other names published for RAD53: LSD1, MEC2, SPK1, YPL153C
RAD53 LITERATURE TOPICS
- Curated Literature
- Genetics/Cell Biology
- Nucleic Acid Information
- Gene Product Information
- Related Genes/Proteins
- Research Aids
- Other Features
- Strains/Constructs
- Techniques and Reagents
- Genome-wide Analysis
- Proteome-wide Analysis
- Other Topics
- Additional Information
RAD53 - Strains/Constructs (220)
| Reference | Other Genes Addressed |
|---|---|
| Myung K and Kolodner RD (2002) Suppression of genome instability by redundant S-phase checkpoint pathways in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 99(7):4500-7 | |
| Sidorova JM and Breeden LL (2002) Precocious S-phase entry in budding yeast prolongs replicative state and increases dependence upon Rad53 for viability. Genetics 160(1):123-36 | |
| Sogo JM, et al. (2002) Fork reversal and ssDNA accumulation at stalled replication forks owing to checkpoint defects. Science 297(5581):599-602 | |
| Zhao X and Rothstein R (2002) The Dun1 checkpoint kinase phosphorylates and regulates the ribonucleotide reductase inhibitor Sml1. Proc Natl Acad Sci U S A 99(6):3746-51 | |
| Alcasabas AA, et al. (2001) Mrc1 transduces signals of DNA replication stress to activate Rad53. Nat Cell Biol 3(11):958-65 | |
| Clerici M, et al. (2001) Hyperactivation of the yeast DNA damage checkpoint by TEL1 and DDC2 overexpression. EMBO J 20(22):6485-98 | |
| De Sanctis V, et al. (2001) Cell cycle arrest determines the intensity of the global transcriptional response of Saccharomyces cerevisiae to ionizing radiation. Radiat Res 156(4):379-87 | |
| Heun P, et al. (2001) Chromosome dynamics in the yeast interphase nucleus. Science 294(5549):2181-6 | |
| Hu F, et al. (2001) Asf1 links Rad53 to control of chromatin assembly. Genes Dev 15(9):1061-6 | |
| Li B and Reese JC (2001) Ssn6-Tup1 regulates RNR3 by positioning nucleosomes and affecting the chromatin structure at the upstream repression sequence. J Biol Chem 276(36):33788-97 | |
| Myung K, et al. (2001) Suppression of spontaneous chromosomal rearrangements by S phase checkpoint functions in Saccharomyces cerevisiae. Cell 104(3):397-408 | |
| Pike BL, et al. (2001) Role of the N-terminal forkhead-associated domain in the cell cycle checkpoint function of the Rad53 kinase. J Biol Chem 276(17):14019-26 | |
| Tercero JA and Diffley JF (2001) Regulation of DNA replication fork progression through damaged DNA by the Mec1/Rad53 checkpoint. Nature 412(6846):553-7 | |
| Wang Y, et al. (2001) Antitumor drug adozelesin differentially affects active and silent origins of DNA replication in yeast checkpoint kinase mutants. Cancer Res 61(9):3787-94 | |
| Zhao X, et al. (2001) The ribonucleotide reductase inhibitor Sml1 is a new target of the Mec1/Rad53 kinase cascade during growth and in response to DNA damage. EMBO J 20(13):3544-53 | |
| van Brabant AJ, et al. (2001) An origin-deficient yeast artificial chromosome triggers a cell cycle checkpoint. Mol Cell 7(4):705-13 | |
| Craven RJ and Petes TD (2000) Involvement of the checkpoint protein Mec1p in silencing of gene expression at telomeres in Saccharomyces cerevisiae. Mol Cell Biol 20(7):2378-84 | |
| Frei C and Gasser SM (2000) The yeast Sgs1p helicase acts upstream of Rad53p in the DNA replication checkpoint and colocalizes with Rad53p in S-phase-specific foci. Genes Dev 14(1):81-96 | |
| Marsolier MC, et al. (2000) Involvement of the PP2C-like phosphatase Ptc2p in the DNA checkpoint pathways of Saccharomyces cerevisiae. Genetics 154(4):1523-32 | |
| Mieczkowski P, et al. (2000) Expression of UMP1 is inducible by DNA damage and required for resistance of S. cerevisiae cells to UV light. Curr Genet 38(2):53-9 | |
| Ohya T, et al. (2000) Structure and function of the fourth subunit (Dpb4p) of DNA polymerase epsilon in Saccharomyces cerevisiae. Nucleic Acids Res 28(20):3846-52 | |
| Simon JA, et al. (2000) Differential toxicities of anticancer agents among DNA repair and checkpoint mutants of Saccharomyces cerevisiae. Cancer Res 60(2):328-33 | |
| Wang P, et al. (2000) II. Structure and specificity of the interaction between the FHA2 domain of Rad53 and phosphotyrosyl peptides. J Mol Biol 302(4):927-40 | |
| Zhao X, et al. (2000) Mutational and structural analyses of the ribonucleotide reductase inhibitor Sml1 define its Rnr1 interaction domain whose inactivation allows suppression of mec1 and rad53 lethality. Mol Cell Biol 20(23):9076-83 | |
| Zhu H, et al. (2000) Analysis of yeast protein kinases using protein chips. Nat Genet 26(3):283-9 | |
| Dohrmann PR, et al. (1999) RAD53 regulates DBF4 independently of checkpoint function in Saccharomyces cerevisiae. Genetics 151(3):965-77 | |
| Gardner R, et al. (1999) RAD53, DUN1 and PDS1 define two parallel G2/M checkpoint pathways in budding yeast. EMBO J 18(11):3173-85 | |
| Grossmann KF, et al. (1999) Cisplatin DNA cross-links do not inhibit S-phase and cause only a G2/M arrest in Saccharomyces cerevisiae. Mutat Res 434(1):29-39 | |
| Neecke H, et al. (1999) Cell cycle progression in the presence of irreparable DNA damage is controlled by a Mec1- and Rad53-dependent checkpoint in budding yeast. EMBO J 18(16):4485-97 | |
| Pellicioli A, et al. (1999) Activation of Rad53 kinase in response to DNA damage and its effect in modulating phosphorylation of the lagging strand DNA polymerase. EMBO J 18(22):6561-72 |





