RAD53/YPL153C Literature Guide Help

Other names published for RAD53: LSD1, MEC2, SPK1, YPL153C

RAD53 - Strains/Constructs (220)

ReferenceOther Genes Addressed
Luke B, et al.  (2006) The cullin Rtt101p promotes replication fork progression through damaged DNA and natural pause sites. Curr Biol 16(8):786-92
Ma JL, et al.  (2006) Activation of the checkpoint kinase Rad53 by the phosphatidyl inositol kinase-like kinase Mec1. J Biol Chem 281(7):3954-63
Maas NL, et al.  (2006) Cell cycle and checkpoint regulation of histone H3 K56 acetylation by Hst3 and Hst4. Mol Cell 23(1):109-19
Schmidt KH, et al.  (2006) Control of translocations between highly diverged genes by Sgs1, the Saccharomyces cerevisiae homolog of the Bloom's syndrome protein. Mol Cell Biol 26(14):5406-20
Smolka MB, et al.  (2006) An FHA domain-mediated protein interaction network of Rad53 reveals its role in polarized cell growth. J Cell Biol 175(5):743-53
Woolstencroft RN, et al.  (2006) Ccr4 contributes to tolerance of replication stress through control of CRT1 mRNA poly(A) tail length. J Cell Sci 119(Pt 24):5178-92
de Bruin RA, et al.  (2006) Constraining G1-specific transcription to late G1 phase: the MBF-associated corepressor Nrm1 acts via negative feedback. Mol Cell 23(4):483-96
Archambault V, et al.  (2005) Disruption of mechanisms that prevent rereplication triggers a DNA damage response. Mol Cell Biol 25(15):6707-21
Bachant J, et al.  (2005) The yeast S phase checkpoint enables replicating chromosomes to bi-orient and restrain spindle extension during S phase distress. J Cell Biol 168(7):999-1012
Bjergbaek L, et al.  (2005) Mechanistically distinct roles for Sgs1p in checkpoint activation and replication fork maintenance. EMBO J 24(2):405-17
Carter CD, et al.  (2005) Loss of SOD1 and LYS7 sensitizes Saccharomyces cerevisiae to hydroxyurea and DNA damage agents and downregulates MEC1 pathway effectors. Mol Cell Biol 25(23):10273-85
Chang M, et al.  (2005) RMI1/NCE4, a suppressor of genome instability, encodes a member of the RecQ helicase/Topo III complex. EMBO J 24(11):2024-33
Cobb JA, et al.  (2005) Replisome instability, fork collapse, and gross chromosomal rearrangements arise synergistically from Mec1 kinase and RecQ helicase mutations. Genes Dev 19(24):3055-69
Corda Y, et al.  (2005) Inactivation of Ku-mediated end joining suppresses mec1Delta lethality by depleting the ribonucleotide reductase inhibitor Sml1 through a pathway controlled by Tel1 kinase and the Mre11 complex. Mol Cell Biol 25(23):10652-64
Cotta-Ramusino C, et al.  (2005) Exo1 processes stalled replication forks and counteracts fork reversal in checkpoint-defective cells. Mol Cell 17(1):153-9
Fasullo M, et al.  (2005) Saccharomyces cerevisiae RAD53 (CHK2) but not CHK1 is required for double-strand break-initiated SCE and DNA damage-associated SCE after exposure to X rays and chemical agents. DNA Repair (Amst) 4(11):1240-51
Flott S and Rouse J  (2005) Slx4 becomes phosphorylated after DNA damage in a Mec1/Tel1-dependent manner and is required for repair of DNA alkylation damage. Biochem J 391(Pt 2):325-33
Gingras AC, et al.  (2005) A novel, evolutionarily conserved protein phosphatase complex involved in cisplatin sensitivity. Mol Cell Proteomics 4(11):1725-40
Grandin N, et al.  (2005) Activation of Mrc1, a mediator of the replication checkpoint, by telomere erosion. Biol Cell 97(10):799-814
Guo Y, et al.  (2005) Expression of a human cytochrome p450 in yeast permits analysis of pathways for response to and repair of aflatoxin-induced DNA damage. Mol Cell Biol 25(14):5823-33
Huang ME and Kolodner RD  (2005) A biological network in Saccharomyces cerevisiae prevents the deleterious effects of endogenous oxidative DNA damage. Mol Cell 17(5):709-20
Liu B, et al.  (2005) A yeast polyamine acetyltransferase. J Biol Chem 280(17):16659-64
Nedelcheva MN, et al.  (2005) Uncoupling of unwinding from DNA synthesis implies regulation of MCM helicase by Tof1/Mrc1/Csm3 checkpoint complex. J Mol Biol 347(3):509-21
Petin VG and Kim JK  (2005) Liquid holding recovery kinetics in wild-type and radiosensitive mutants of the yeast Saccharomyces exposed to low- and high-LET radiations. Mutat Res 570(1):1-8
Ptacek J, et al.  (2005) Global analysis of protein phosphorylation in yeast. Nature 438(7068):679-84
Shaag A, et al.  (2005) Functional and genomic approaches reveal an ancient CHEK2 allele associated with breast cancer in the Ashkenazi Jewish population. Hum Mol Genet 14(4):555-63
Sharp JA, et al.  (2005) Regulation of histone deposition proteins Asf1/Hir1 by multiple DNA damage checkpoint kinases in Saccharomyces cerevisiae. Genetics 171(3):885-99
Sweeney FD, et al.  (2005) Saccharomyces cerevisiae Rad9 acts as a Mec1 adaptor to allow Rad53 activation. Curr Biol 15(15):1364-75
Taylor SD, et al.  (2005) The conserved Mec1/Rad53 nuclear checkpoint pathway regulates mitochondrial DNA copy number in Saccharomyces cerevisiae. Mol Biol Cell 16(6):3010-8
Tourriere H, et al.  (2005) Mrc1 and Tof1 promote replication fork progression and recovery independently of Rad53. Mol Cell 19(5):699-706