TOP2/YNL088W Literature Guide Help

Other names published for TOP2: TOR3, TRF3, DNA topoisomerase 2, YNL088W

TOP2 - Strains/Constructs (69)

ReferenceOther Genes Addressed
Bock LJ, et al.  (2012) Cnn1 inhibits the interactions between the KMN complexes of the yeast kinetochore. Nat Cell Biol 14(6):614-24
Hashash N, et al.  (2012) Topoisomerase II- and Condensin-Dependent Breakage of MEC1(ATR)-Sensitive Fragile Sites Occurs Independently of Spindle Tension, Anaphase, or Cytokinesis. PLoS Genet 8(10):e1002978
Joshi RS, et al.  (2012) Topoisomerase II is required for the production of long Pol II gene transcripts in yeast. Nucleic Acids Res 40(16):7907-15
French SL, et al.  (2011) Distinguishing the Roles of Topoisomerases I and II in Relief of Transcription-Induced Torsional Stress in Yeast rRNA Genes. Mol Cell Biol 31(3):482-94
Kegel A, et al.  (2011) Chromosome length influences replication-induced topological stress. Nature 471(7338):392-6
Sperling AS, et al.  (2011) Topoisomerase II binds nucleosome-free DNA and acts redundantly with topoisomerase I to enhance recruitment of RNA Pol II in budding yeast. Proc Natl Acad Sci U S A 108(31):12693-8
Joshi RS, et al.  (2010) Positional dependence of transcriptional inhibition by DNA torsional stress in yeast chromosomes. EMBO J 29(4):740-8
Renshaw MJ, et al.  (2010) Condensins Promote Chromosome Recoiling during Early Anaphase to Complete Sister Chromatid Separation. Dev Cell 19(2):232-244
Bermejo R, et al.  (2009) Genome-organizing factors Top2 and Hmo1 prevent chromosome fragility at sites of S phase transcription. Cell 138(5):870-84
Furniss K, et al.  (2009) Assaying Topoisomerase II Checkpoints in Yeast. Methods Mol Biol 582:167-87
Mendoza M, et al.  (2009) A mechanism for chromosome segregation sensing by the NoCut checkpoint. Nat Cell Biol 11(4):477-83
Baxter J and Diffley JF  (2008) Topoisomerase II inactivation prevents the completion of DNA replication in budding yeast. Mol Cell 30(6):790-802
Breslow DK, et al.  (2008) A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods 5(8):711-8
D'Ambrosio C, et al.  (2008) Condensin-Dependent rDNA Decatenation Introduces a Temporal Pattern to Chromosome Segregation. Curr Biol 18(14):1084-9
Rogojina AT and Nitiss JL  (2008) Isolation and Characterization of mAMSA-hypersensitive Mutants: CYTOTOXICITY OF Top2 COVALENT COMPLEXES CONTAINING DNA SINGLE STRAND BREAKS. J Biol Chem 283(43):29239-50
Takahashi Y and Strunnikov A  (2008) In vivo modeling of polysumoylation uncovers targeting of Topoisomerase II to the nucleolus via optimal level of SUMO modification. Chromosoma 117(2):189-98
Takahashi Y, et al.  (2008) Cooperation of sumoylated chromosomal proteins in rDNA maintenance. PLoS Genet 4(10):e1000215
Warsi TH, et al.  (2008) DNA topoisomerase II is a determinant of the tensile properties of yeast centromeric chromatin and the tension checkpoint. Mol Biol Cell 19(10):4421-33
Ivanov D and Nasmyth K  (2007) A physical assay for sister chromatid cohesion in vitro. Mol Cell 27(2):300-10
Andrews CA, et al.  (2006) A mitotic topoisomerase II checkpoint in budding yeast is required for genome stability but acts independently of Pds1/securin. Genes Dev 20(9):1162-74
Machin F, et al.  (2006) Transcription of ribosomal genes can cause nondisjunction. J Cell Biol 173(6):893-903
Salceda J, et al.  (2006) Topoisomerase II, not topoisomerase I, is the proficient relaxase of nucleosomal DNA. EMBO J 25(11):2575-83
Takahashi Y, et al.  (2006) SIZ1/SIZ2 control of chromosome transmission fidelity is mediated by the sumoylation of topoisomerase II. Genetics 172(2):783-94
Jiang X  (2005) Random mutagenesis of the B'A' core domain of yeast DNA topoisomerase II and large-scale screens of mutants resistant to the anticancer drug etoposide. Biochem Biophys Res Commun 327(2):597-603
Lu HR, et al.  (2005) Reactive oxygen species elicit apoptosis by concurrently disrupting topoisomerase II and DNA-dependent protein kinase. Mol Pharmacol 68(4):983-94
Vaughn J, et al.  (2005) Stability of the topoisomerase II closed clamp conformation may influence DNA-stimulated ATP hydrolysis. J Biol Chem 280(12):11920-9
Hossain MS, et al.  (2004) DNA topoisomerase II is required for the G0-to-S phase transition in Drosophila Schneider cells, but not in yeast. Genes Cells 9(10):905-17
Moro S, et al.  (2004) Interaction model for anthracycline activity against DNA topoisomerase II. Biochemistry 43(23):7503-13
Suda N, et al.  (2004) The alpha4 residues of human DNA topoisomerase IIalpha function in enzymatic activity and anticancer drug sensitivity. Nucleic Acids Res 32(5):1767-73
Sullivan M, et al.  (2004) Cdc14 phosphatase induces rDNA condensation and resolves cohesin-independent cohesion during budding yeast anaphase. Cell 117(4):471-82