Other names published for TOP2: TOR3, TRF3, DNA topoisomerase 2, YNL088W
TOP2 LITERATURE TOPICS
- Curated Literature
- Genetics/Cell Biology
- Nucleic Acid Information
- Gene Product Information
- Related Genes/Proteins
- Research Aids
- Other Features
- Strains/Constructs
- Techniques and Reagents
- Genome-wide Analysis
- Proteome-wide Analysis
- Other Topics
- Additional Information
TOP2 - Strains/Constructs (69)
| Reference | Other Genes Addressed |
|---|---|
| Bock LJ, et al. (2012) Cnn1 inhibits the interactions between the KMN complexes of the yeast kinetochore. Nat Cell Biol 14(6):614-24 | |
| Hashash N, et al. (2012) Topoisomerase II- and Condensin-Dependent Breakage of MEC1(ATR)-Sensitive Fragile Sites Occurs Independently of Spindle Tension, Anaphase, or Cytokinesis. PLoS Genet 8(10):e1002978 | |
| Joshi RS, et al. (2012) Topoisomerase II is required for the production of long Pol II gene transcripts in yeast. Nucleic Acids Res 40(16):7907-15 | |
| French SL, et al. (2011) Distinguishing the Roles of Topoisomerases I and II in Relief of Transcription-Induced Torsional Stress in Yeast rRNA Genes. Mol Cell Biol 31(3):482-94 | |
| Kegel A, et al. (2011) Chromosome length influences replication-induced topological stress. Nature 471(7338):392-6 | |
| Sperling AS, et al. (2011) Topoisomerase II binds nucleosome-free DNA and acts redundantly with topoisomerase I to enhance recruitment of RNA Pol II in budding yeast. Proc Natl Acad Sci U S A 108(31):12693-8 | |
| Joshi RS, et al. (2010) Positional dependence of transcriptional inhibition by DNA torsional stress in yeast chromosomes. EMBO J 29(4):740-8 | |
| Renshaw MJ, et al. (2010) Condensins Promote Chromosome Recoiling during Early Anaphase to Complete Sister Chromatid Separation. Dev Cell 19(2):232-244 | |
| Bermejo R, et al. (2009) Genome-organizing factors Top2 and Hmo1 prevent chromosome fragility at sites of S phase transcription. Cell 138(5):870-84 | |
| Furniss K, et al. (2009) Assaying Topoisomerase II Checkpoints in Yeast. Methods Mol Biol 582:167-87 | |
| Mendoza M, et al. (2009) A mechanism for chromosome segregation sensing by the NoCut checkpoint. Nat Cell Biol 11(4):477-83 | |
| Baxter J and Diffley JF (2008) Topoisomerase II inactivation prevents the completion of DNA replication in budding yeast. Mol Cell 30(6):790-802 | |
| Breslow DK, et al. (2008) A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods 5(8):711-8 | |
| D'Ambrosio C, et al. (2008) Condensin-Dependent rDNA Decatenation Introduces a Temporal Pattern to Chromosome Segregation. Curr Biol 18(14):1084-9 | |
| Rogojina AT and Nitiss JL (2008) Isolation and Characterization of mAMSA-hypersensitive Mutants: CYTOTOXICITY OF Top2 COVALENT COMPLEXES CONTAINING DNA SINGLE STRAND BREAKS. J Biol Chem 283(43):29239-50 | |
| Takahashi Y and Strunnikov A (2008) In vivo modeling of polysumoylation uncovers targeting of Topoisomerase II to the nucleolus via optimal level of SUMO modification. Chromosoma 117(2):189-98 | |
| Takahashi Y, et al. (2008) Cooperation of sumoylated chromosomal proteins in rDNA maintenance. PLoS Genet 4(10):e1000215 | |
| Warsi TH, et al. (2008) DNA topoisomerase II is a determinant of the tensile properties of yeast centromeric chromatin and the tension checkpoint. Mol Biol Cell 19(10):4421-33 | |
| Ivanov D and Nasmyth K (2007) A physical assay for sister chromatid cohesion in vitro. Mol Cell 27(2):300-10 | |
| Andrews CA, et al. (2006) A mitotic topoisomerase II checkpoint in budding yeast is required for genome stability but acts independently of Pds1/securin. Genes Dev 20(9):1162-74 | |
| Machin F, et al. (2006) Transcription of ribosomal genes can cause nondisjunction. J Cell Biol 173(6):893-903 | |
| Salceda J, et al. (2006) Topoisomerase II, not topoisomerase I, is the proficient relaxase of nucleosomal DNA. EMBO J 25(11):2575-83 | |
| Takahashi Y, et al. (2006) SIZ1/SIZ2 control of chromosome transmission fidelity is mediated by the sumoylation of topoisomerase II. Genetics 172(2):783-94 | |
| Jiang X (2005) Random mutagenesis of the B'A' core domain of yeast DNA topoisomerase II and large-scale screens of mutants resistant to the anticancer drug etoposide. Biochem Biophys Res Commun 327(2):597-603 | |
| Lu HR, et al. (2005) Reactive oxygen species elicit apoptosis by concurrently disrupting topoisomerase II and DNA-dependent protein kinase. Mol Pharmacol 68(4):983-94 | |
| Vaughn J, et al. (2005) Stability of the topoisomerase II closed clamp conformation may influence DNA-stimulated ATP hydrolysis. J Biol Chem 280(12):11920-9 | |
| Hossain MS, et al. (2004) DNA topoisomerase II is required for the G0-to-S phase transition in Drosophila Schneider cells, but not in yeast. Genes Cells 9(10):905-17 | |
| Moro S, et al. (2004) Interaction model for anthracycline activity against DNA topoisomerase II. Biochemistry 43(23):7503-13 | |
| Suda N, et al. (2004) The alpha4 residues of human DNA topoisomerase IIalpha function in enzymatic activity and anticancer drug sensitivity. Nucleic Acids Res 32(5):1767-73 | |
| Sullivan M, et al. (2004) Cdc14 phosphatase induces rDNA condensation and resolves cohesin-independent cohesion during budding yeast anaphase. Cell 117(4):471-82 |




