SSA2/YLL024C Literature Guide Help

Other names published for SSA2: YG102, Hsp70 family chaperone SSA2, YLL024C

SSA2 - Strains/Constructs (81)

ReferenceOther Genes Addressed
Park SH, et al.  (2007) The cytoplasmic Hsp70 chaperone machinery subjects misfolded and endoplasmic reticulum import-incompetent proteins to degradation via the ubiquitin-proteasome system. Mol Biol Cell 18(1):153-65
Behrends C, et al.  (2006) Chaperonin TRiC promotes the assembly of polyQ expansion proteins into nontoxic oligomers. Mol Cell 23(6):887-97
Hung GC and Masison DC  (2006) N-terminal domain of yeast Hsp104 chaperone is dispensable for thermotolerance and prion propagation but necessary for curing prions by Hsp104 overexpression. Genetics 173(2):611-20
Karniely S, et al.  (2006) The presequence of fumarase is exposed to the cytosol during import into mitochondria. J Mol Biol 358(2):396-405
Matsumoto R, et al.  (2006) Search for novel stress-responsive protein components using a yeast mutant lacking two cytosolic Hsp70 genes, SSA1 and SSA2. Mol Cells 21(3):381-8
Allen KD, et al.  (2005) Hsp70 chaperones as modulators of prion life cycle: novel effects of Ssa and Ssb on the Saccharomyces cerevisiae prion [PSI+]. Genetics 169(3):1227-42
Flower TR, et al.  (2005) Heat shock prevents alpha-synuclein-induced apoptosis in a yeast model of Parkinson's disease. J Mol Biol 351(5):1081-100
Matsumoto R, et al.  (2005) The stress response against denatured proteins in the deletion of cytosolic chaperones SSA1/2 is different from heat-shock response in Saccharomyces cerevisiae. BMC Genomics 6():141
Roberts BT, et al.  (2004) [URE3] prion propagation is abolished by a mutation of the primary cytosolic Hsp70 of budding yeast. Yeast 21(2):107-17
Schwock J, et al.  (2004) Interaction of 6-phosphofructokinase with cytosolic proteins of Saccharomyces cerevisiae. Yeast 21(6):483-94
Gilbert CS, et al.  (2003) The budding yeast Rad9 checkpoint complex: chaperone proteins are required for its function. EMBO Rep 4(10):953-8
Li XS, et al.  (2003) Candida albicans Ssa1/2p is the cell envelope binding protein for human salivary histatin 5. J Biol Chem 278(31):28553-61
Sass E, et al.  (2003) Folding of fumarase during mitochondrial import determines its dual targeting in yeast. J Biol Chem 278(46):45109-16
Taxis C, et al.  (2003) Use of modular substrates demonstrates mechanistic diversity and reveals differences in chaperone requirement of ERAD. J Biol Chem 278(38):35903-13
Unno K, et al.  (2003) Increased expression of Hsp70 for resistance to deuterium oxide in a yeast mutant cell line. Biol Pharm Bull 26(6):799-802
Wegele H, et al.  (2003) Sti1 is a novel activator of the Ssa proteins. J Biol Chem 278(28):25970-6
Meriin AB, et al.  (2002) Huntington toxicity in yeast model depends on polyglutamine aggregation mediated by a prion-like protein Rnq1. J Cell Biol 157(6):997-1004
Grandin N and Charbonneau M  (2001) Hsp90 levels affect telomere length in yeast. Mol Genet Genomics 265(1):126-34
Hjorth-Sorensen B, et al.  (2001) Activation of heat shock transcription factor in yeast is not influenced by the levels of expression of heat shock proteins. Mol Microbiol 39(4):914-23
Lutz W, et al.  (2001) The role of heat shock protein 70 in vitamin D receptor function. Biochem Biophys Res Commun 282(5):1211-9
Sadeghi N, et al.  (2001) Thermal blockage of viruslike particle formation for the yeast retrotransposon Ty3 reveals differences in the cellular stress response. Arch Virol 146(10):1919-34
Zhang Y, et al.  (2001) Hsp70 molecular chaperone facilitates endoplasmic reticulum-associated protein degradation of cystic fibrosis transmembrane conductance regulator in yeast. Mol Biol Cell 12(5):1303-14
Brown CR, et al.  (2000) The heat shock protein Ssa2p is required for import of fructose-1, 6-bisphosphatase into Vid vesicles. J Cell Biol 150(1):65-76
Jung G, et al.  (2000) A role for cytosolic hsp70 in yeast [PSI(+)] prion propagation and [PSI(+)] as a cellular stress. Genetics 156(2):559-70
Krobitsch S and Lindquist S  (2000) Aggregation of huntingtin in yeast varies with the length of the polyglutamine expansion and the expression of chaperone proteins. Proc Natl Acad Sci U S A 97(4):1589-94
Satyanarayana C, et al.  (2000) Cytosolic Hsp70s are involved in the transport of aminopeptidase 1 from the cytoplasm into the vacuole. FEBS Lett 470(3):232-8
Schmidt PJ, et al.  (2000) Copper activation of superoxide dismutase 1 (SOD1) in vivo. Role for protein-protein interactions with the copper chaperone for SOD1. J Biol Chem 275(43):33771-6
Horst M, et al.  (1999) Import into and degradation of cytosolic proteins by isolated yeast vacuoles. Mol Biol Cell 10(9):2879-89
Baxter BK and Craig EA  (1998) Isolation of UBP3, encoding a de-ubiquitinating enzyme, as a multicopy suppressor of a heat-shock mutant strain of S. cerevisiae. Curr Genet 33(6):412-9
Baxter BK and Craig EA  (1998) Suppression of an Hsp70 mutant phenotype in Saccharomyces cerevisiae through loss of function of the chromatin component Sin1p/Spt2p. J Bacteriol 180(24):6484-92