APN1/YKL114C Literature Guide Help

Other names published for APN1: DNA-(apurinic or apyrimidinic site) lyase APN1, YKL114C

APN1 - Strains/Constructs (107)

ReferenceOther Genes Addressed
Ishchenko AA, et al.  (2004) Alpha-anomeric deoxynucleotides, anoxic products of ionizing radiation, are substrates for the endonuclease IV-type AP endonucleases. Biochemistry 43(48):15210-6
Monti P, et al.  (2004) Nucleotide excision repair defect influences lethality and mutagenicity induced by Me-lex, a sequence-selective N3-adenine methylating agent in the absence of base excision repair. Biochemistry 43(19):5592-9
Tong AH, et al.  (2004) Global mapping of the yeast genetic interaction network. Science 303(5659):808-13
Garcia-Rubio M, et al.  (2003) Recombinogenic effects of DNA-damaging agents are synergistically increased by transcription in Saccharomyces cerevisiae. New insights into transcription-associated recombination. Genetics 165(2):457-66
Guillet M and Boiteux S  (2003) Origin of endogenous DNA abasic sites in Saccharomyces cerevisiae. Mol Cell Biol 23(22):8386-94
Jilani A, et al.  (2003) Characterization of two independent amino acid substitutions that disrupt the DNA repair functions of the yeast Apn1. Biochemistry 42(21):6436-45
Karumbati AS, et al.  (2003) The role of yeast DNA 3'-phosphatase Tpp1 and rad1/Rad10 endonuclease in processing spontaneous and induced base lesions. J Biol Chem 278(33):31434-43
Maclean MJ, et al.  (2003) Base excision repair activities required for yeast to attain a full chronological life span. Aging Cell 2(2):93-104
Morey NJ, et al.  (2003) Delineating the requirements for spontaneous DNA damage resistance pathways in genome maintenance and viability in Saccharomyces cerevisiae. Genetics 164(2):443-55
Roth TJ, et al.  (2003) Human-yeast chimeric repair protein protects mammalian cells against alkylating agents: enhancement of MGMT protection. Cancer Gene Ther 10(8):603-10
Yu SL, et al.  (2003) The stalling of transcription at abasic sites is highly mutagenic. Mol Cell Biol 23(1):382-8
Chang M, et al.  (2002) A genome-wide screen for methyl methanesulfonate-sensitive mutants reveals genes required for S phase progression in the presence of DNA damage. Proc Natl Acad Sci U S A 99(26):16934-9
Fleming JA, et al.  (2002) Complementary whole-genome technologies reveal the cellular response to proteasome inhibition by PS-341. Proc Natl Acad Sci U S A 99(3):1461-6
Guillet M and Boiteux S  (2002) Endogenous DNA abasic sites cause cell death in the absence of Apn1, Apn2 and Rad1/Rad10 in Saccharomyces cerevisiae. EMBO J 21(11):2833-41
Hendricks CA, et al.  (2002) The S. cerevisiae Mag1 3-methyladenine DNA glycosylase modulates susceptibility to homologous recombination. DNA Repair (Amst) 1(8):645-59
Liu C, et al.  (2002) Repair of topoisomerase I covalent complexes in the absence of the tyrosyl-DNA phosphodiesterase Tdp1. Proc Natl Acad Sci U S A 99(23):14970-5
O'Brien TJ, et al.  (2002) Effects of hexavalent chromium on the survival and cell cycle distribution of DNA repair-deficient S. cerevisiae. DNA Repair (Amst) 1(8):617-27
Vance JR and Wilson TE  (2001) Repair of DNA strand breaks by the overlapping functions of lesion-specific and non-lesion-specific DNA 3' phosphatases. Mol Cell Biol 21(21):7191-8
Vongsamphanh R, et al.  (2001) Pir1p mediates translocation of the yeast Apn1p endonuclease into the mitochondria to maintain genomic stability. Mol Cell Biol 21(5):1647-55
Xiao W, et al.  (2001) Deletion of the MAG1 DNA glycosylase gene suppresses alkylation-induced killing and mutagenesis in yeast cells lacking AP endonucleases. Mutat Res 487(3-4):137-47
Davidson JF and Schiestl RH  (2000) Mis-targeting of multiple gene disruption constructs containing hisG. Curr Genet 38(4):188-90
Kozhin SA, et al.  (2000) [RAD29 and RAD31--new genes from Saccharomyces cerevisiae yeasts, participating in control of DNA repair. II. Clarification of possible functions of these genes] Genetika 36(8):1025-32
Morey NJ, et al.  (2000) Genetic analysis of transcription-associated mutation in Saccharomyces cerevisiae. Genetics 154(1):109-20
Pinson B, et al.  (2000) Identification of genes affecting selenite toxicity and resistance in Saccharomyces cerevisiae. Mol Microbiol 36(3):679-87
Scheller J, et al.  (2000) MPH1, a yeast gene encoding a DEAH protein, plays a role in protection of the genome from spontaneous and chemically induced damage. Genetics 155(3):1069-81
Simon JA, et al.  (2000) Differential toxicities of anticancer agents among DNA repair and checkpoint mutants of Saccharomyces cerevisiae. Cancer Res 60(2):328-33
Torres-Ramos CA, et al.  (2000) Evidence for the involvement of nucleotide excision repair in the removal of abasic sites in yeast. Mol Cell Biol 20(10):3522-8
Bennett RA  (1999) The Saccharomyces cerevisiae ETH1 gene, an inducible homolog of exonuclease III that provides resistance to DNA-damaging agents and limits spontaneous mutagenesis. Mol Cell Biol 19(3):1800-9
Swanson RL, et al.  (1999) Overlapping specificities of base excision repair, nucleotide excision repair, recombination, and translesion synthesis pathways for DNA base damage in Saccharomyces cerevisiae. Mol Cell Biol 19(4):2929-35
Wilson TE and Lieber MR  (1999) Efficient processing of DNA ends during yeast nonhomologous end joining. Evidence for a DNA polymerase beta (Pol4)-dependent pathway. J Biol Chem 274(33):23599-609