MGA2/YIR033W Literature Guide Help

Other names published for MGA2: YIR033W

MGA2 - Strains/Constructs (24)

ReferenceOther Genes Addressed
Micolonghi C, et al.  (2012) A dual signalling pathway for the hypoxic expression of lipid genes, dependent on the glucose sensor Rag4, is revealed by the analysis of the KlMGA2 gene in Kluyveromyces lactis. Microbiology 158(Pt 7):1734-44
Reimand J, et al.  (2012) m:Explorer - multinomial regression models reveal positive and negative regulators of longevity in yeast quiescence. Genome Biol 13(6):R55
Dymond JS, et al.  (2011) Synthetic chromosome arms function in yeast and generate phenotypic diversity by design.LID - 10.1038/nature10403 [doi] Nature ()
Hickman MJ, et al.  (2011) The Hog1 mitogen-activated protein kinase mediates a hypoxic response in Saccharomyces cerevisiae. Genetics 188(2):325-38
Wang X, et al.  (2011) Intersection of the multivesicular body pathway and lipid homeostasis in RNA replication by a positive-strand RNA virus. J Virol 85(11):5494-503
Rice C, et al.  (2010) A role for MGA2, but not SPT23, in activation of transcription of ERG1 in Saccharomyces cerevisiae. Biochem Biophys Res Commun 403(3-4):293-7
Zheng J, et al.  (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
Bhattacharya S, et al.  (2009) Identification of lysines within membrane-anchored Mga2p120 that are targets of Rsp5p ubiquitination and mediate mobilization of tethered Mga2p90. J Mol Biol 385(3):718-25
Kelley R and Ideker T  (2009) Genome-wide fitness and expression profiling implicate Mga2 in adaptation to hydrogen peroxide. PLoS Genet 5(5):e1000488
Kaliszewski P, et al.  (2008) Rsp5p ubiquitin ligase and the transcriptional activators Spt23p and Mga2p are involved in co-regulation of biosynthesis of end products of the mevalonate pathway and triacylglycerol in yeast Saccharomyces cerevisiae. Biochim Biophys Acta 1781(10):627-34
Musso G, et al.  (2008) The extensive and condition-dependent nature of epistasis among whole-genome duplicates in yeast. Genome Res 18(7):1092-9
Ruotolo R, et al.  (2008) Membrane transporters and protein traffic networks differentially affecting metal tolerance: a genomic phenotyping study in yeast. Genome Biol 9(4):R67
Yu L, et al.  (2008) Chemical-genetic profiling of imidazo[1,2-a]pyridines and -pyrimidines reveals target pathways conserved between yeast and human cells. PLoS Genet 4(11):e1000284
Guzy RD, et al.  (2007) Mitochondrial complex III is required for hypoxia-induced ROS production and gene transcription in yeast. Antioxid Redox Signal 9(9):1317-28
Jesch SA, et al.  (2006) Multiple endoplasmic reticulum-to-nucleus signaling pathways coordinate phospholipid metabolism with gene expression by distinct mechanisms. J Biol Chem 281(33):24070-83
Oh CS and Martin CE  (2006) Candida albicans Spt23p controls the expression of the Ole1p Delta9 fatty acid desaturase and regulates unsaturated fatty acid biosynthesis. J Biol Chem 281(11):7030-9
Kandasamy P, et al.  (2004) Regulation of unsaturated fatty acid biosynthesis in Saccharomyces: the endoplasmic reticulum membrane protein, Mga2p, a transcription activator of the OLE1 gene, regulates the stability of the OLE1 mRNA through exosome-mediated mechanisms. J Biol Chem 279(35):36586-92
Shcherbik N, et al.  (2004) A single PXY motif located within the carboxyl terminus of Spt23p and Mga2p mediates a physical and functional interaction with ubiquitin ligase Rsp5p. J Biol Chem 279(51):53892-8
Goehring AS, et al.  (2003) Synthetic lethal analysis implicates Ste20p, a p21-activated potein kinase, in polarisome activation. Mol Biol Cell 14(4):1501-16
Jiang Y, et al.  (2002) Mga2p processing by hypoxia and unsaturated fatty acids in Saccharomyces cerevisiae: impact on LORE-dependent gene expression. Eukaryot Cell 1(3):481-90
Chellappa R, et al.  (2001) The membrane proteins, Spt23p and Mga2p, play distinct roles in the activation of Saccharomyces cerevisiae OLE1 gene expression. Fatty acid-mediated regulation of Mga2p activity is independent of its proteolytic processing into a soluble transcription activator. J Biol Chem 276(47):43548-56
Jiang Y, et al.  (2001) MGA2 is involved in the low-oxygen response element-dependent hypoxic induction of genes in Saccharomyces cerevisiae. Mol Cell Biol 21(18):6161-9
Dula ML and Holmes SG  (2000) MGA2 and SPT23 are modifiers of transcriptional silencing in yeast. Genetics 156(3):933-41
Zhang S, et al.  (1999) MGA2 or SPT23 is required for transcription of the delta9 fatty acid desaturase gene, OLE1, and nuclear membrane integrity in Saccharomyces cerevisiae. Genetics 151(2):473-83