ERG9/YHR190W Literature Guide Help

Other names published for ERG9: bifunctional farnesyl-diphosphate farnesyltransferase/squalene synthase, YHR190W

ERG9 - Strains/Constructs (28)

ReferenceOther Genes Addressed
Scalcinati G, et al.  (2012) Combined metabolic engineering of precursor and co-factor supply to increase alpha-santalene production by Saccharomyces cerevisiae. Microb Cell Fact 11(1):117
Scalcinati G, et al.  (2012) Dynamic control of gene expression in Saccharomyces cerevisiae engineered for the production of plant sesquitepene a-santalene in a fed-batch mode. Metab Eng 14(2):91-103
Ta TM, et al.  (2012) Accumulation of squalene is associated with the clustering of lipid droplets. FEBS J 279(22):4231-44
Westfall PJ, et al.  (2012) Production of amorphadiene in yeast, and its conversion to dihydroartemisinic acid, precursor to the antimalarial agent artemisinin. Proc Natl Acad Sci U S A 109(3):E111-8
Albertsen L, et al.  (2011) Diversion of Flux toward Sesquiterpene Production in Saccharomyces cerevisiae by Fusion of Host and Heterologous Enzymes. Appl Environ Microbiol 77(3):1033-1040
Babiskin AH and Smolke CD  (2011) A synthetic library of RNA control modules for predictable tuning of gene expression in yeast. Mol Syst Biol 7():471
Madsen KM, et al.  (2011) Linking Genotype and Phenotype of Saccharomyces cerevisiae Strains Reveals Metabolic Engineering Targets and Leads to Triterpene Hyper-Producers. PLoS One 6(3):e14763
Pu J, et al.  (2011) Interactomic study on interaction between lipid droplets and mitochondria. Protein Cell 2(6):487-96
Asadollahi MA, et al.  (2010) Enhancement of farnesyl diphosphate pool as direct precursor of sesquiterpenes through metabolic engineering of the mevalonate pathway in Saccharomyces cerevisiae. Biotechnol Bioeng 106(1):86-96
Garza RM, et al.  (2009) Geranylgeranyl Pyrophosphate Is a Potent Regulator of HRD-dependent 3-Hydroxy-3-methylglutaryl-CoA Reductase Degradation in Yeast. J Biol Chem 284(51):35368-80
Muramatsu M, et al.  (2009) Alkaline pH enhances farnesol production by Saccharomyces cerevisiae. J Biosci Bioeng 108(1):52-5
Pan JJ, et al.  (2009) Recombinant squalene synthase. synthesis of cyclopentyl non-head-to-tail triterpenes. J Org Chem 74(19):7562-5
Song L  (2009) Recovery of E,E-farnesol from cultures of yeast erg9 mutants: extraction with polymeric beads and purification by normal-phase chromatography. Biotechnol Prog 25(4):1111-4
Asadollahi MA, et al.  (2008) Production of plant sesquiterpenes in Saccharomyces cerevisiae: effect of ERG9 repression on sesquiterpene biosynthesis. Biotechnol Bioeng 99(3):666-77
Muramatsu M, et al.  (2008) Accumulation of prenyl alcohols by terpenoid biosynthesis inhibitors in various microorganisms. Appl Microbiol Biotechnol 80(4):589-95
Muramatsu M, et al.  (2008) Various oils and detergents enhance the microbial production of farnesol and related prenyl alcohols. J Biosci Bioeng 106(3):263-7
Paradise EM, et al.  (2008) Redirection of flux through the FPP branch-point in Saccharomyces cerevisiae by down-regulating squalene synthase. Biotechnol Bioeng 100(2):371-8
Song L  (2006) Reduction of background interference in the spectrophotometric assay of mevalonate kinase. Anal Bioanal Chem 384(6):1444-5
Szkopinska A, et al.  (2006) Interplay between the cis-prenyltransferases and polyprenol reductase in the yeast Saccharomyces cerevisiae. Biochimie 88(3-4):271-6
Beh CT and Rine J  (2004) A role for yeast oxysterol-binding protein homologs in endocytosis and in the maintenance of intracellular sterol-lipid distribution. J Cell Sci 117(Pt 14):2983-96
Song L  (2003) Detection of farnesyl diphosphate accumulation in yeast ERG9 mutants. Anal Biochem 317(2):180-5
Merkulov S, et al.  (2000) Cloning and characterization of the Yarrowia lipolytica squalene synthase (SQS1) gene and functional complementation of the Saccharomyces cerevisiae erg9 mutation. Yeast 16(3):197-206
Grabowska D, et al.  (1998) Effect of squalene synthase gene disruption on synthesis of polyprenols in Saccharomyces cerevisiae. FEBS Lett 434(3):406-8
Szkopinska A, et al.  (1993) The deficiency of sterol biosynthesis in Saccharomyces cerevisiae affects the synthesis of glycosyl derivatives of dolichyl phosphates. FEMS Microbiol Lett 112(3):325-8
Zhang D, et al.  (1993) Yeast squalene synthase: expression, purification, and characterization of soluble recombinant enzyme. Arch Biochem Biophys 304(1):133-43
Fegueur M, et al.  (1991) Isolation and primary structure of the ERG9 gene of Saccharomyces cerevisiae encoding squalene synthetase. Curr Genet 20(5):365-72
Jennings SM, et al.  (1991) Molecular cloning and characterization of the yeast gene for squalene synthetase. Proc Natl Acad Sci U S A 88(14):6038-42
Karst F and Lacroute F  (1977) Ertosterol biosynthesis in Saccharomyces cerevisiae: mutants deficient in the early steps of the pathway. Mol Gen Genet 154(3):269-77