Other names published for ERG11: CYP51, sterol 14-demethylase, YHR007C
ERG11 LITERATURE TOPICS
- Curated Literature
- Genetics/Cell Biology
- Nucleic Acid Information
- Gene Product Information
- Related Genes/Proteins
- Research Aids
- Other Features
- Strains/Constructs
- Techniques and Reagents
- Genome-wide Analysis
- Proteome-wide Analysis
- Other Topics
- Additional Information
ERG11 - Strains/Constructs (37)
| Reference | Other Genes Addressed |
|---|---|
| Fiori A and Van Dijck P (2012) Potent synergistic effect of doxycycline with fluconazole against Candida albicans is mediated by interference with iron homeostasis. Antimicrob Agents Chemother 56(7):3785-96 | |
| Hoepfner D, et al. (2012) An integrated approach for identification and target validation of antifungal compounds active against Erg11p. Antimicrob Agents Chemother 56(8):4233-40 | |
| Nkinin SW, et al. (2011) Pneumocystis carinii sterol 14a-demethylase activity in Saccharomyces cerevisiae erg11 knockout mutant: sterol biochemistry. J Eukaryot Microbiol 58(4):383-92 | |
| Spitzer M, et al. (2011) Cross-species discovery of syncretic drug combinations that potentiate the antifungal fluconazole. Mol Syst Biol 7():499 | |
| Martel CM, et al. (2010) Complementation of a Saccharomyces cerevisiae ERG11/CYP51 (Sterol 14{alpha}-Demethylase) Doxycycline-Regulated Mutant and Screening of the Azole Sensitivity of Aspergillus fumigatus Isoenzymes CYP51A and CYP51B. Antimicrob Agents Chemother 54(11):4920-3 | |
| Shakoury-Elizeh M, et al. (2010) Metabolic response to iron deficiency in Saccharomyces cerevisiae. J Biol Chem 285(19):14823-33 | |
| Kitahama Y, et al. (2009) The Construction and Characterization of Self-Sufficient Lanosterol 14-Demethylase Fusion Proteins Consisting of Yeast CYP51 and Its Reductase. Biol Pharm Bull 32(4):558-63 | |
| Breslow DK, et al. (2008) A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods 5(8):711-8 | |
| Hoon S, et al. (2008) An integrated platform of genomic assays reveals small-molecule bioactivities. Nat Chem Biol 4(8):498-506 | |
| Paluszynski JP, et al. (2008) Genetic prerequisites for additive or synergistic actions of 5-fluorocytosine and fluconazole in baker's yeast. Microbiology 154(Pt 10):3154-64 | |
| Warrilow A, et al. (2008) Expression and Characterization of CYP51, the Ancient Sterol 14-demethylase Activity for Cytochromes P450 (CYP), in the White-Rot Fungus Phanerochaete chrysosporium. Lipids 43(12):1143-53 | |
| Wu TK, et al. (2008) Protein plasticity: a single amino acid substitution in the Saccharomyces cerevisiae oxidosqualene-lanosterol cyclase generates protosta-13(17),24-dien-3beta-ol, a rearrangement product. Org Lett 10(12):2529-32 | |
| Davierwala AP, et al. (2005) The synthetic genetic interaction spectrum of essential genes. Nat Genet 37(10):1147-52 | |
| Mallory JC, et al. (2005) Dap1p, a heme-binding protein that regulates the cytochrome P450 protein Erg11p/Cyp51p in Saccharomyces cerevisiae. Mol Cell Biol 25(5):1669-79 | |
| Ott RG, et al. (2005) Flux of sterol intermediates in a yeast strain deleted of the lanosterol C-14 demethylase Erg11p. Biochim Biophys Acta 1735(2):111-8 | |
| Lum PY, et al. (2004) Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes. Cell 116(1):121-37 | |
| Parsons AB, et al. (2004) Integration of chemical-genetic and genetic interaction data links bioactive compounds to cellular target pathways. Nat Biotechnol 22(1):62-9 | |
| Revankar SG, et al. (2004) Cloning and characterization of the lanosterol 14alpha-demethylase (ERG11) gene in Cryptococcus neoformans. Biochem Biophys Res Commun 324(2):719-28 | |
| Buckner FS, et al. (2003) Cloning and analysis of Trypanosoma cruzi lanosterol 14alpha-demethylase. Mol Biochem Parasitol 132(2):75-81 | |
| Morales IJ, et al. (2003) Characterization of a lanosterol 14 alpha-demethylase from Pneumocystis carinii. Am J Respir Cell Mol Biol 29(2):232-8 | |
| Veen M, et al. (2003) Combined overexpression of genes of the ergosterol biosynthetic pathway leads to accumulation of sterols in Saccharomyces cerevisiae. FEMS Yeast Res 4(1):87-95 | |
| Homma K, et al. (2000) Evidence for recycling of cytochrome P450 sterol 14-demethylase from the cis-Golgi compartment to the endoplasmic reticulum (ER) upon saturation of the ER-retention mechanism. J Biochem 127(5):747-54 | |
| Giaever G, et al. (1999) Genomic profiling of drug sensitivities via induced haploinsufficiency. Nat Genet 21(3):278-83 | |
| Kontoyiannis DP, et al. (1999) Overexpression of Erg11p by the regulatable GAL1 promoter confers fluconazole resistance in Saccharomyces cerevisiae. Antimicrob Agents Chemother 43(11):2798-800 | |
| Launhardt H, et al. (1998) Drug-induced phenotypes provide a tool for the functional analysis of yeast genes. Yeast 14(10):935-42 | |
| Venkateswarlu K, et al. (1998) NADPH cytochrome P-450 oxidoreductase and susceptibility to ketoconazole. Antimicrob Agents Chemother 42(7):1756-61 | |
| Venkateswarlu K, et al. (1997) Characterization of Saccharomyces cerevisiae CYP51 and a CYP51 fusion protein with NADPH cytochrome P-450 oxidoreductase expressed in Escherichia coli. Antimicrob Agents Chemother 41(4):776-80 | |
| Kelly SL, et al. (1995) Mode of action and resistance to azole antifungals associated with the formation of 14 alpha-methylergosta-8,24(28)-dien-3 beta,6 alpha-diol. Biochem Biophys Res Commun 207(3):910-5 | |
| Doignon F, et al. (1993) Resistance to imidazoles and triazoles in Saccharomyces cerevisiae as a new dominant marker. Plasmid 30(3):224-33 | |
| Weber JM, et al. (1992) Factors affecting homologous overexpression of the Saccharomyces cerevisiae lanosterol 14 alpha-demethylase gene. Yeast 8(7):519-33 | |





