Other names published for UBC6: DOA2, E2 ubiquitin-conjugating protein UBC6, YER100W
UBC6 LITERATURE TOPICS
- Curated Literature
- Genetics/Cell Biology
- Nucleic Acid Information
- Gene Product Information
- Related Genes/Proteins
- Research Aids
- Other Features
- Strains/Constructs
- Techniques and Reagents
- Genome-wide Analysis
- Proteome-wide Analysis
- Other Topics
- Additional Information
UBC6 - Strains/Constructs (38)
| Reference | Other Genes Addressed |
|---|---|
| Khmelinskii A, et al. (2012) Tandem fluorescent protein timers for in vivo analysis of protein dynamics.LID - 10.1038/nbt.2281 [doi] Nat Biotechnol () | |
| Rubenstein EM, et al. (2012) Aberrant substrate engagement of the ER translocon triggers degradation by the Hrd1 ubiquitin ligase. J Cell Biol 197(6):761-73 | |
| Fang NN, et al. (2011) Hul5 HECT ubiquitin ligase plays a major role in the ubiquitylation and turnover of cytosolic misfolded proteins. Nat Cell Biol 13(11):1344-52 | |
| Kreft SG and Hochstrasser M (2011) An unusual transmembrane helix in the endoplasmic reticulum ubiquitin ligase Doa10 modulates degradation of its cognate E2 enzyme. J Biol Chem 286(23):20163-74 | |
| Wang Y, et al. (2011) Ubiquitin-dependent Proteasomal Degradation of Human Liver Cytochrome P450 2E1: IDENTIFICATION OF SITES TARGETED FOR PHOSPHORYLATION AND UBIQUITINATION. J Biol Chem 286(11):9443-56 | |
| Adle DJ, et al. (2009) Cadmium-mediated rescue from ER-associated degradation induces expression of its exporter. Proc Natl Acad Sci U S A 106(25):10189-94 | |
| Kim HC and Huibregtse JM (2009) Polyubiquitination by HECT E3s and the determinants of chain type specificity. Mol Cell Biol 29(12):3307-18 | |
| Kornmann B, et al. (2009) An ER-mitochondria tethering complex revealed by a synthetic biology screen. Science 325(5939):477-81 | |
| Metzger MB and Michaelis S (2009) Analysis of quality control substrates in distinct cellular compartments reveals a unique role for Rpn4p in tolerating misfolded membrane proteins. Mol Biol Cell 20(3):1006-19 | |
| Xu P, et al. (2009) Quantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradation. Cell 137(1):133-45 | |
| Duennwald ML and Lindquist S (2008) Impaired ERAD and ER stress are early and specific events in polyglutamine toxicity. Genes Dev 22(23):3308-3319 | |
| Nakatsukasa K, et al. (2008) Dissecting the ER-associated degradation of a misfolded polytopic membrane protein. Cell 132(1):101-12 | |
| Schuldiner M, et al. (2008) The GET complex mediates insertion of tail-anchored proteins into the ER membrane. Cell 134(4):634-45 | |
| Allen KD, et al. (2007) Effects of ubiquitin system alterations on the formation and loss of a yeast prion. J Biol Chem 282(5):3004-13 | |
| Braun S and Jentsch S (2007) SM-protein-controlled ER-associated degradation discriminates between different SNAREs. EMBO Rep 8(12):1176-82 | |
| Kota J, et al. (2007) Membrane chaperone Shr3 assists in folding amino acid permeases preventing precocious ERAD. J Cell Biol 176(5):617-28 | |
| Rodrigo-Brenni MC and Morgan DO (2007) Sequential E2s Drive Polyubiquitin Chain Assembly on APC Targets. Cell 130(1):127-39 | |
| Hiraishi H, et al. (2006) Enhancement of Stress Tolerance in Saccharomyces cerevisiae by Overexpression of Ubiquitin Ligase Rsp5 and Ubiquitin-Conjugating Enzymes. Biosci Biotechnol Biochem 70(11):2762-5 | |
| Liao M, et al. (2006) Endoplasmic reticulum-associated degradation of cytochrome P450 CYP3A4 in Saccharomyces cerevisiae: further characterization of cellular participants and structural determinants. Mol Pharmacol 69(6):1897-904 | |
| Kiel JA, et al. (2005) Ubiquitination of the peroxisomal targeting signal type 1 receptor, Pex5p, suggests the presence of a quality control mechanism during peroxisomal matrix protein import. J Biol Chem 280(3):1921-30 | |
| Wang Q and Chang A (2003) Substrate recognition in ER-associated degradation mediated by Eps1, a member of the protein disulfide isomerase family. EMBO J 22(15):3792-802 | |
| Wang Y, et al. (2003) Regulation of Ste7 ubiquitination by Ste11 phosphorylation and the Skp1-Cullin-F-box complex. J Biol Chem 278(25):22284-9 | |
| Botero D, et al. (2002) Ubc6p and ubc7p are required for normal and substrate-induced endoplasmic reticulum-associated degradation of the human selenoprotein type 2 iodothyronine monodeiodinase. Mol Endocrinol 16(9):1999-2007 | |
| Lenk U, et al. (2002) A role for mammalian Ubc6 homologues in ER-associated protein degradation. J Cell Sci 115(Pt 14):3007-14 | |
| Jakob CA, et al. (2001) Htm1p, a mannosidase-like protein, is involved in glycoprotein degradation in yeast. EMBO Rep 2(5):423-30 | |
| Walter J, et al. (2001) Sec61p-independent degradation of the tail-anchored ER membrane protein Ubc6p. EMBO J 20(12):3124-31 | |
| Lenk U and Sommer T (2000) Ubiquitin-mediated proteolysis of a short-lived regulatory protein depends on its cellular localization. J Biol Chem 275(50):39403-10 | |
| Wilhovsky S, et al. (2000) HRD gene dependence of endoplasmic reticulum-associated degradation. Mol Biol Cell 11(5):1697-708 | |
| Amshoff C, et al. (1999) Cycloheximide, a new tool to dissect specific steps in ER-associated degradation of different substrates. Biol Chem 380(6):669-77 | |
| Wang Q and Chang A (1999) Eps1, a novel PDI-related protein involved in ER quality control in yeast. EMBO J 18(21):5972-82 |




