MEC1/YBR136W Literature Guide Help

Other names published for MEC1: ESR1, SAD3, RAD31, YBR136W

MEC1 - Regulatory Role (96)

Results: 1 - 30 of 96 records
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ReferenceOther Genes Addressed
Berens TJ and Toczyski DP  (2012) Colocalization of Mec1 and Mrc1 is sufficient for Rad53 phosphorylation in vivo. Mol Biol Cell 23(6):1058-67
Tkach JM, et al.  (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat Cell Biol 14(9):966-76
Chen X, et al.  (2011) Cell cycle regulation of DNA double-strand break end resection by Cdk1-dependent Dna2 phosphorylation.LID - 10.1038/nsmb.2105 [doi] Nat Struct Mol Biol ()
Minca EC and Kowalski D  (2011) Replication fork stalling by bulky DNA damage: localization at active origins and checkpoint modulation. Nucleic Acids Res 39(7):2610-23
Pfander B and Diffley JF  (2011) Dpb11 coordinates Mec1 kinase activation with cell cycle-regulated Rad9 recruitment.LID - 10.1038/emboj.2011.345 [doi] EMBO J ()
Searle JS, et al.  (2011) Proteins in the Nutrient-Sensing and DNA Damage Checkpoint Pathways Cooperate to Restrain Mitotic Progression following DNA Damage. PLoS Genet 7(7):e1002176
Tao R, et al.  (2011) Xbp1-mediated histone H4 deacetylation contributes to DNA double-strand break repair in yeast. Cell Res 21(11):1619-33
Chen SH, et al.  (2010) A proteome-wide analysis of kinase-substrate network in the DNA damage response. J Biol Chem 285(17):12803-12
Janke R, et al.  (2010) A truncated DNA-damage-signaling response is activated after DSB formation in the G1 phase of Saccharomyces cerevisiae. Nucleic Acids Res 38(7):2302-13
Levesque N, et al.  (2010) Loss of H3 K79 trimethylation leads to suppression of Rtt107-dependent DNA damage sensitivity through the translesion synthesis pathway. J Biol Chem 285(45):35113-22
Lopez-Mosqueda J, et al.  (2010) Cdc5 blocks in vivo Rad53 activity, but not in situ activity (ISA). Cell Cycle 9(21):4266-8
Nguyen VC, et al.  (2010) Replication stress checkpoint signaling controls tRNA gene transcription. Nat Struct Mol Biol 17(8):976-81
Ohouo PY, et al.  (2010) DNA damage signaling recruits the Rtt107-Slx4 scaffolds via Dpb11 to mediate replication stress response. Mol Cell 39(2):300-6
Randell JC, et al.  (2010) Mec1 is one of multiple kinases that prime the Mcm2-7 helicase for phosphorylation by Cdc7. Mol Cell 40(3):353-63
Szilard RK, et al.  (2010) Systematic identification of fragile sites via genome-wide location analysis of gamma-H2AX. Nat Struct Mol Biol 17(3):299-305
Taschner M, et al.  (2010) A role for checkpoint kinase-dependent Rad26 phosphorylation in transcription-coupled DNA repair in Saccharomyces cerevisiae. Mol Cell Biol 30(2):436-46
Toh GW, et al.  (2010) Mec1/Tel1-dependent phosphorylation of Slx4 stimulates Rad1-Rad10-dependent cleavage of non-homologous DNA tails. DNA Repair (Amst) 9(6):718-26
Vidanes GM, et al.  (2010) CDC5 Inhibits the Hyperphosphorylation of the Checkpoint Kinase Rad53, Leading to Checkpoint Adaptation. PLoS Biol 8(1):e1000286
Chen SH and Zhou H  (2009) Reconstitution of Rad53 Activation by Mec1 through Adaptor Protein Mrc1. J Biol Chem 284(28):18593-604
Lin YH, et al.  (2009) Recruitment of rad51 and rad52 to short telomeres triggers a mec1-mediated hypersensitivity to double-stranded DNA breaks in senescent budding yeast. PLoS One 4(12):e8224
Makovets S and Blackburn EH  (2009) DNA damage signalling prevents deleterious telomere addition at DNA breaks. Nat Cell Biol 11(11):1383-6
Pereira E, et al.  (2009) Conserved ATRMec1 phosphorylation-independent activation of Chk1 by single amino acid substitution in the GD domain. Cell Cycle 8(11):1788-93
di Domenico EG, et al.  (2009) The Mec1p and Tel1p checkpoint kinases allow humanized yeast to tolerate chronic telomere dysfunctions by suppressing telomere fusions. DNA Repair (Amst) 8(2):209-18
Carballo JA, et al.  (2008) Phosphorylation of the axial element protein Hop1 by Mec1/Tel1 ensures meiotic interhomolog recombination. Cell 132(5):758-70
Kim EM and Burke DJ  (2008) DNA damage activates the SAC in an ATM/ATR-dependent manner, independently of the kinetochore. PLoS Genet 4(2):e1000015
Lazzaro F, et al.  (2008) Histone methyltransferase Dot1 and Rad9 inhibit single-stranded DNA accumulation at DSBs and uncapped telomeres. EMBO J 27(10):1502-12
Mordes DA, et al.  (2008) Dpb11 activates the Mec1-Ddc2 complex. Proc Natl Acad Sci U S A 105(48):18730-4
Suter B, et al.  (2008) Exploring protein phosphorylation in response to DNA damage using differentially tagged yeast arrays. Biotechniques 45(5):581-4
Flott S, et al.  (2007) Phosphorylation of Slx4 by Mec1 and Tel1 regulates the single-strand annealing mode of DNA repair in budding yeast. Mol Cell Biol 27(18):6433-45
Morrison AJ, et al.  (2007) Mec1/Tel1 phosphorylation of the INO80 chromatin remodeling complex influences DNA damage checkpoint responses. Cell 130(3):499-511
Results: 1 - 30 of 96 records
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