MAC1/YMR021C Literature Guide Help

Other names published for MAC1: CUA1, YMR021C

MAC1 - Regulatory Role (29)

ReferenceOther Genes Addressed
Liu L, et al.  (2012) Low-affinity copper transporter CTR2 is regulated by copper-sensing transcription factor Mac1p in Saccharomyces cerevisiae. Biochem Biophys Res Commun 420(3):600-4
Contador CA, et al.  (2011) Identification of transcription factors perturbed by the synthesis of high levels of a foreign protein in yeast saccharomyces cerevisiae. Biotechnol Prog 27(4):925-36
Fendt SM, et al.  (2010) Unraveling condition-dependent networks of transcription factors that control metabolic pathway activity in yeast. Mol Syst Biol 6():432
Heo DH, et al.  (2010) Cadmium regulates copper homoeostasis by inhibiting the activity of Mac1, a transcriptional activator of the copper regulon, in Saccharomyces cerevisiae. Biochem J 431(2):257-65
Crisp RJ, et al.  (2006) Recruitment of Tup1p and Cti6p regulates heme-deficient expression of Aft1p target genes. EMBO J 25(3):512-21
Yu H and Gerstein M  (2006) Genomic analysis of the hierarchical structure of regulatory networks. Proc Natl Acad Sci U S A 103(40):14724-31
Siddharthan R, et al.  (2005) PhyloGibbs: a Gibbs sampling motif finder that incorporates phylogeny. PLoS Comput Biol 1(7):e67
Yu T and Li KC  (2005) Inference of transcriptional regulatory network by two-stage constrained space factor analysis. Bioinformatics 21(21):4033-8
De Freitas JM, et al.  (2004) Exploratory and confirmatory gene expression profiling of mac1Delta. J Biol Chem 279(6):4450-8
Luscombe NM, et al.  (2004) Genomic analysis of regulatory network dynamics reveals large topological changes. Nature 431(7006):308-12
Marvin ME, et al.  (2004) The CaCTR1 gene is required for high-affinity iron uptake and is transcriptionally controlled by a copper-sensing transactivator encoded by CaMAC1. Microbiology 150(Pt 7):2197-208
Marvin ME, et al.  (2003) The Candida albicans CTR1 gene encodes a functional copper transporter. Microbiology 149(Pt 6):1461-74
Ishida S, et al.  (2002) Uptake of the anticancer drug cisplatin mediated by the copper transporter Ctr1 in yeast and mammals. Proc Natl Acad Sci U S A 99(22):14298-302
Yonkovich J, et al.  (2002) Copper ion-sensing transcription factor Mac1p post-translationally controls the degradation of its target gene product Ctr1p. J Biol Chem 277(27):23981-4
Heredia J, et al.  (2001) Phosphorylation and Cu+ coordination-dependent DNA binding of the transcription factor Mac1p in the regulation of copper transport. J Biol Chem 276(12):8793-7
Gross C, et al.  (2000) Identification of the copper regulon in Saccharomyces cerevisiae by DNA microarrays. J Biol Chem 275(41):32310-6
Georgatsou E and Alexandraki D  (1999) Regulated expression of the Saccharomyces cerevisiae Fre1p/Fre2p Fe/Cu reductase related genes. Yeast 15(7):573-84
Jamison McDaniels CP, et al.  (1999) The yeast transcription factor Mac1 binds to DNA in a modular fashion. J Biol Chem 274(38):26962-7
Serpe M, et al.  (1999) Structure-function analysis of the protein-binding domains of Mac1p, a copper-dependent transcriptional activator of copper uptake in Saccharomyces cerevisiae. J Biol Chem 274(41):29211-9
Jensen LT and Winge DR  (1998) Identification of a copper-induced intramolecular interaction in the transcription factor Mac1 from Saccharomyces cerevisiae. EMBO J 17(18):5400-8
Martins LJ, et al.  (1998) Metalloregulation of FRE1 and FRE2 homologs in Saccharomyces cerevisiae. J Biol Chem 273(37):23716-21
Pena MM, et al.  (1998) Dynamic regulation of copper uptake and detoxification genes in Saccharomyces cerevisiae. Mol Cell Biol 18(5):2514-23
Zhu Z, et al.  (1998) Copper differentially regulates the activity and degradation of yeast Mac1 transcription factor. J Biol Chem 273(3):1277-80
Georgatsou E, et al.  (1997) The yeast Fre1p/Fre2p cupric reductases facilitate copper uptake and are regulated by the copper-modulated Mac1p activator. J Biol Chem 272(21):13786-92
Graden JA and Winge DR  (1997) Copper-mediated repression of the activation domain in the yeast Mac1p transcription factor. Proc Natl Acad Sci U S A 94(11):5550-5
Labbe S, et al.  (1997) Copper-specific transcriptional repression of yeast genes encoding critical components in the copper transport pathway. J Biol Chem 272(25):15951-8
Yamaguchi-Iwai Y, et al.  (1997) Homeostatic regulation of copper uptake in yeast via direct binding of MAC1 protein to upstream regulatory sequences of FRE1 and CTR1. J Biol Chem 272(28):17711-8
Hassett R and Kosman DJ  (1995) Evidence for Cu(II) reduction as a component of copper uptake by Saccharomyces cerevisiae. J Biol Chem 270(1):128-34
Jungmann J, et al.  (1993) MAC1, a nuclear regulatory protein related to Cu-dependent transcription factors is involved in Cu/Fe utilization and stress resistance in yeast. EMBO J 12(13):5051-6