KAR2/YJL034W Literature Guide Help

Other names published for KAR2: GRP78, BIP, Hsp70 family ATPase KAR2, YJL034W

KAR2 - Regulatory Role (5)

ReferenceOther Genes Addressed
Pincus D, et al.  (2010) BiP binding to the ER-stress sensor Ire1 tunes the homeostatic behavior of the unfolded protein response. PLoS Biol 8(7):e1000415
Nakatsukasa K, et al.  (2004) Roles of O-mannosylation of aberrant proteins in reduction of the load for endoplasmic reticulum chaperones in yeast. J Biol Chem 279(48):49762-72
Steel GJ, et al.  (2004) Coordinated activation of Hsp70 chaperones. Science 303(5654):98-101
Kimata Y, et al.  (2003) Genetic evidence for a role of BiP/Kar2 that regulates Ire1 in response to accumulation of unfolded proteins. Mol Biol Cell 14(6):2559-69
Okamura K, et al.  (2000) Dissociation of Kar2p/BiP from an ER sensory molecule, Ire1p, triggers the unfolded protein response in yeast. Biochem Biophys Res Commun 279(2):445-50