RAD6/YGL058W Literature Guide Help

Other names published for RAD6: UBC2, PSO8, E2 ubiquitin-conjugating protein RAD6, YGL058W

RAD6 - Regulatory Role (26)

ReferenceOther Genes Addressed
Venters BJ, et al.  (2011) A comprehensive genomic binding map of gene and chromatin regulatory proteins in Saccharomyces. Mol Cell 41(4):480-92
Davies AA, et al.  (2010) Ubiquitylation of the 9-1-1 checkpoint clamp is independent of rad6-rad18 and DNA damage. Cell 141(6):1080-7
Hwang CS, et al.  (2010) The N-end rule pathway is mediated by a complex of the RING-type Ubr1 and HECT-type Ufd4 ubiquitin ligases. Nat Cell Biol 12(12):1177-85
Hwang CS, et al.  (2009) Two proteolytic pathways regulate DNA repair by cotargeting the Mgt1 alkylguanine transferase. Proc Natl Acad Sci U S A 106(7):2142-7
Kats ES, et al.  (2009) The Saccharomyces cerevisiae Rad6 postreplication repair and Siz1/Srs2 homologous recombination-inhibiting pathways process DNA damage that arises in asf1 mutants. Mol Cell Biol 29(19):5226-37
Shishkin AA, et al.  (2009) Large-scale expansions of Friedreich's ataxia GAA repeats in yeast. Mol Cell 35(1):82-92
Fu Y, et al.  (2008) Rad6-Rad18 mediates a eukaryotic SOS response by ubiquitinating the 9-1-1 checkpoint clamp. Cell 133(4):601-11
Geng F and Tansey WP  (2008) Polyubiquitylation of Histone H2B. Mol Biol Cell 19(9):3616-24
Ju D and Xie Y  (2006) Identification of the preferential ubiquitination site and ubiquitin-dependent degradation signal of Rpn4. J Biol Chem 281(16):10657-62
Giannattasio M, et al.  (2005) The DNA damage checkpoint response requires histone H2B ubiquitination by Rad6-Bre1 and H3 methylation by Dot1. J Biol Chem 280(11):9879-86
Laribee RN, et al.  (2005) BUR kinase selectively regulates H3 K4 trimethylation and H2B ubiquitylation through recruitment of the PAF elongation complex. Curr Biol 15(16):1487-93
Moye-Rowley WS  (2005) Retrograde regulation of multidrug resistance in Saccharomyces cerevisiae. Gene 354:15-21
Jacobson SJ, et al.  (2004) Functional analyses of chromatin modifications in yeast. Methods Enzymol 377:3-55
Schneider J, et al.  (2004) Global proteomic analysis of S. cerevisiae (GPS) to identify proteins required for histone modifications. Methods Enzymol 377:227-34
Stelter P and Ulrich HD  (2003) Control of spontaneous and damage-induced mutagenesis by SUMO and ubiquitin conjugation. Nature 425(6954):188-91
Ng HH, et al.  (2002) Ubiquitination of histone H2B by Rad6 is required for efficient Dot1-mediated methylation of histone H3 lysine 79. J Biol Chem 277(38):34655-7
Turner SD, et al.  (2002) The E2 ubiquitin conjugase Rad6 is required for the ArgR/Mcm1 repression of ARG1 transcription. Mol Cell Biol 22(12):4011-9
Ptak C, et al.  (2001) Creation of a pluripotent ubiquitin-conjugating enzyme. Mol Cell Biol 21(19):6537-48
Brusky J, et al.  (2000) UBC13, a DNA-damage-inducible gene, is a member of the error-free postreplication repair pathway in Saccharomyces cerevisiae. Curr Genet 37(3):168-74
Kaplun L, et al.  (2000) Functions of the DNA damage response pathway target Ho endonuclease of yeast for degradation via the ubiquitin-26S proteasome system. Proc Natl Acad Sci U S A 97(18):10077-82
Robzyk K, et al.  (2000) Rad6-dependent ubiquitination of histone H2B in yeast. Science 287(5452):501-4
Ulrich HD and Jentsch S  (2000) Two RING finger proteins mediate cooperation between ubiquitin-conjugating enzymes in DNA repair. EMBO J 19(13):3388-97
Xiao W, et al.  (2000) The Saccharomyces cerevisiae RAD6 group is composed of an error-prone and two error-free postreplication repair pathways. Genetics 155(4):1633-41
Kornitzer D, et al.  (1994) Regulated degradation of the transcription factor Gcn4. EMBO J 13(24):6021-30
Haas AL, et al.  (1991) Ubiquitin conjugation by the yeast RAD6 and CDC34 gene products. Comparison to their putative rabbit homologs, E2(20K) AND E2(32K). J Biol Chem 266(8):5104-12
Jentsch S, et al.  (1987) The yeast DNA repair gene RAD6 encodes a ubiquitin-conjugating enzyme. Nature 329(6135):131-4