MOT2/YER068W Literature Guide Help

Other names published for MOT2: NOT4, SIG1, CCR4-NOT core ubiquitin-protein ligase subunit MOT2, YER068W

MOT2 - Regulatory Role (18)

ReferenceOther Genes Addressed
Cooper KF, et al.  (2012) Oxidative-stress-induced nuclear to cytoplasmic relocalization is required for Not4-dependent cyclin C destruction. J Cell Sci 125(Pt 4):1015-26
Gulshan K, et al.  (2012) Proteolytic degradation of the Yap1 transcription factor is regulated by subcellular localization and the E3 ubiquitin ligase Not4. J Biol Chem 287(32):26796-805
Panasenko OO and Collart MA  (2012) Presence of Not5 and ubiquitinated Rps7A in polysome fractions depends upon the Not4 E3 ligase. Mol Microbiol 83(3):640-53
Venters BJ, et al.  (2011) A comprehensive genomic binding map of gene and chromatin regulatory proteins in Saccharomyces. Mol Cell 41(4):480-92
Azzouz N, et al.  (2009) The CCR4-NOT complex physically and functionally interacts with TRAMP and the nuclear exosome. PLoS One 4(8):e6760
Mersman DP, et al.  (2009) Polyubiquitination of the demethylase Jhd2 controls histone methylation and gene expression. Genes Dev 23(8):951-62
Laribee RN, et al.  (2007) CCR4/NOT complex associates with the proteasome and regulates histone methylation. Proc Natl Acad Sci U S A 104(14):5836-41
Lenssen E, et al.  (2007) The Ccr4-Not Complex Regulates Skn7 through Srb10 Kinase. Eukaryot Cell 6(12):2251-9
Mulder KW, et al.  (2007) Modulation of Ubc4p/Ubc5p-Mediated Stress Responses by the RING-Finger-Dependent Ubiquitin-Protein Ligase Not4p in Saccharomyces cerevisiae. Genetics 176(1):181-92
Guo X, et al.  (2006) Histone acetylation and transcriptional regulation in the genome of Saccharomyces cerevisiae. Bioinformatics 22(4):392-9
Yu H and Gerstein M  (2006) Genomic analysis of the hierarchical structure of regulatory networks. Proc Natl Acad Sci U S A 103(40):14724-31
Mazzoni C, et al.  (2005) The inactivation of KlNOT4, a Kluyveromyces lactis gene encoding a component of the CCR4-NOT complex, reveals new regulatory functions. Genetics 170(3):1023-32
Muhlrad D and Parker R  (2005) The yeast EDC1 mRNA undergoes deadenylation-independent decapping stimulated by Not2p, Not4p, and Not5p. EMBO J 24(5):1033-45
Dimmer KS, et al.  (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53
Lemaire M and Collart MA  (2000) The TATA-binding protein-associated factor yTafII19p functionally interacts with components of the global transcriptional regulator Ccr4-Not complex and physically interacts with the Not5 subunit. J Biol Chem 275(35):26925-34
Maillet L, et al.  (2000) The essential function of Not1 lies within the Ccr4-Not complex. J Mol Biol 303(2):131-43
Liu HY, et al.  (1998) The NOT proteins are part of the CCR4 transcriptional complex and affect gene expression both positively and negatively. EMBO J 17(4):1096-106
Irie K, et al.  (1994) The yeast MOT2 gene encodes a putative zinc finger protein that serves as a global negative regulator affecting expression of several categories of genes, including mating-pheromone-responsive genes. Mol Cell Biol 14(5):3150-7