SIR2/YDL042C Literature Guide Help

Other names published for SIR2: MAR1, YDL042C

SIR2 - Regulation of (43)

ReferenceOther Genes Addressed
Chang CS, et al.  (2012) Suppression Analysis of esa1 Mutants in Saccharomyces cerevisiae Links NAB3 to Transcriptional Silencing and Nucleolar Functions. G3 (Bethesda) 2(10):1223-32
Stumpferl SW, et al.  (2012) Natural genetic variation in yeast longevity. Genome Res 22(10):1963-73
Sun K, et al.  (2012) Anti-aging effects of hesperidin on Saccharomyces cerevisiae via inhibition of reactive oxygen species and UTH1 gene expression. Biosci Biotechnol Biochem 76(4):640-5
Alba Sorolla M, et al.  (2011) Sir2 is induced by oxidative stress in a yeast model of Huntington disease and its activation reduces protein aggregation. Arch Biochem Biophys 510(1):27-34
Boender LG, et al.  (2011) Cellular responses of Saccharomyces cerevisiae at near-zero growth rates: transcriptome analysis of anaerobic retentostat cultures. FEMS Yeast Res 11(8):603-20
Oppikofer M, et al.  (2011) A dual role of H4K16 acetylation in the establishment of yeast silent chromatin.LID - 10.1038/emboj.2011.170 [doi] EMBO J ()
Xiang L, et al.  (2011) Anti-aging effects of phloridzin, an apple polyphenol, on yeast via the SOD and Sir2 genes. Biosci Biotechnol Biochem 75(5):854-8
Zhu X, et al.  (2011) Mediator influences telomeric silencing and cellular life span. Mol Cell Biol 31(12):2413-21
Dai J, et al.  (2010) Yin and Yang of Histone H2B Roles in Silencing and Longevity: A Tale of Two Arginines. Genetics 186(3):813-28
Miller A, et al.  (2010) Proliferating cell nuclear antigen (PCNA) is required for cell cycle-regulated silent chromatin on replicated and nonreplicated genes. J Biol Chem 285(45):35142-54
Zhou BO, et al.  (2010) SWR1 complex poises heterochromatin boundaries for antisilencing activity propagation. Mol Cell Biol 30(10):2391-400
Li L, et al.  (2009) Budding yeast SSD1-V regulates transcript levels of many longevity genes and extends chronological life span in purified quiescent cells. Mol Biol Cell 20(17):3851-64
Lynch PJ and Rusche LN  (2009) A silencer promotes the assembly of silenced chromatin independently of recruitment. Mol Cell Biol 29(1):43-56
Mazor Y and Kupiec M  (2009) Developmentally regulated MAPK pathways modulate heterochromatin in Saccharomyces cerevisiae. Nucleic Acids Res 37(14):4839-49
Sanders BD, et al.  (2009) Identification and characterization of novel sirtuin inhibitor scaffolds. Bioorg Med Chem 17(19):7031-41
Silva RM, et al.  (2009) The yeast PNC1 longevity gene is up-regulated by mRNA mistranslation. PLoS ONE 4(4):e5212
Verzijlbergen KF, et al.  (2009) Multiple histone modifications in euchromatin promote heterochromatin formation by redundant mechanisms in Saccharomyces cerevisiae. BMC Mol Biol 10:76
Denisenko O and Bomsztyk K  (2008) Epistatic interaction between the K-homology domain protein HEK2 and SIR1 at HMR and telomeres in yeast. J Mol Biol 375(4):1178-87
Raisner RM and Madhani HD  (2008) Genomewide Screen for Negative Regulators of Sirtuin Activity in Saccharomyces cerevisiae Reveals 40 Loci and Links to Metabolism. Genetics 179(4):1933-44
Belenky P, et al.  (2007) Nicotinamide riboside promotes Sir2 silencing and extends lifespan via Nrk and Urh1/Pnp1/Meu1 pathways to NAD+. Cell 129(3):473-84
Medvedik O, et al.  (2007) MSN2 and MSN4 link calorie restriction and TOR to sirtuin-mediated lifespan extension in Saccharomyces cerevisiae. PLoS Biol 5(10):e261
Yang H, et al.  (2007) Design and synthesis of compounds that extend yeast replicative lifespan. Aging Cell 6(1):35-43
Calzari L, et al.  (2006) The Histone Deubiquitinating Enzyme Ubp10 Is Involved in rDNA Locus Control in Saccharomyces cerevisiae by Affecting Sir2p Association. Genetics 174(4):2249-54
Fry CJ, et al.  (2006) The LRS and SIN domains: two structurally equivalent but functionally distinct nucleosomal surfaces required for transcriptional silencing. Mol Cell Biol 26(23):9045-59
Kaeberlein M, et al.  (2005) Substrate-specific activation of sirtuins by resveratrol. J Biol Chem 280(17):17038-45
Michel AH, et al.  (2005) Spontaneous rDNA copy number variation modulates Sir2 levels and epigenetic gene silencing. Genes Dev 19(10):1199-210
Sauve AA, et al.  (2005) Chemical activation of Sir2-dependent silencing by relief of nicotinamide inhibition. Mol Cell 17(4):595-601
Bi X, et al.  (2004) Regulation of transcriptional silencing in yeast by growth temperature. J Mol Biol 344(4):893-905
Dasgupta A, et al.  (2004) Sir Antagonist 1 (San1) is a ubiquitin ligase. J Biol Chem 279(26):26830-8
Gallo CM, et al.  (2004) Nicotinamide clearance by Pnc1 directly regulates Sir2-mediated silencing and longevity. Mol Cell Biol 24(3):1301-12