GCN2/YDR283C Literature Guide Help

Other names published for GCN2: AAS1, NDR2, AAS102, YDR283C

GCN2 - Regulation of (31)

Results: 1 - 30 of 31 records
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ReferenceOther Genes Addressed
Kimpe M, et al.  (2012) Pkh1 interacts with and phosphorylates components of the yeast Gcn2/eIF2a system. Biochem Biophys Res Commun 419(1):89-94
Rodriguez-Hernandez CJ, et al.  (2012) Anti-diabetic and anti-obesity agent sodium tungstate enhances GCN pathway activation through Glc7p inhibition. FEBS Lett 586(3):270-6
Balagopal V and Parker R  (2011) Stm1 modulates translation after 80S formation in Saccharomyces cerevisiae. RNA 17(5):835-42
Sattlegger E, et al.  (2011) Gcn1 and Actin Binding to Yih1: IMPLICATIONS FOR ACTIVATION OF THE eIF2 KINASE GCN2. J Biol Chem 286(12):10341-55
Visweswaraiah J, et al.  (2011) Evidence that eukaryotic translation elongation factor 1A (eEF1A) binds the Gcn2 protein C terminus and inhibits Gcn2 activity. J Biol Chem 286(42):36568-79
Cherkasova V, et al.  (2010) Snf1 promotes phosphorylation of the alpha subunit of eukaryotic translation initiation factor 2 by activating Gcn2 and inhibiting phosphatases Glc7 and Sit4. Mol Cell Biol 30(12):2862-73
Nomura W, et al.  (2010) Methylglyoxal activates Gcn2 to phosphorylate eIF2alpha independently of the TOR pathway in Saccharomyces cerevisiae. Appl Microbiol Biotechnol 86(6):1887-94
Soulard A, et al.  (2010) The Rapamycin-sensitive Phosphoproteome Reveals That TOR Controls Protein Kinase A Toward Some But Not All Substrates. Mol Biol Cell 21(19):3475-86
Garriz A, et al.  (2009) A network of hydrophobic residues impeding helix alphaC rotation maintains latency of kinase Gcn2, which phosphorylates the alpha subunit of translation initiation factor 2. Mol Cell Biol 29(6):1592-607
Mascarenhas C, et al.  (2008) Gcn4 Is Required for the Response to Peroxide Stress in the Yeast Saccharomyces cerevisiae. Mol Biol Cell 19(7):2995-3007
Nomura W, et al.  (2008) Role of Gcn4 for adaptation to methylglyoxal in Saccharomyces cerevisiae: methylglyoxal attenuates protein synthesis through phosphorylation of eIF2alpha. Biochem Biophys Res Commun 376(4):738-42
Sattlegger E and Hinnebusch AG  (2005) Polyribosome binding by GCN1 is required for full activation of eukaryotic translation initiation factor 2{alpha} kinase GCN2 during amino acid starvation. J Biol Chem 280(16):16514-21
Rohde JR, et al.  (2004) TOR controls transcriptional and translational programs via Sap-Sit4 protein phosphatase signaling effectors. Mol Cell Biol 24(19):8332-41
Cherkasova VA and Hinnebusch AG  (2003) Translational control by TOR and TAP42 through dephosphorylation of eIF2alpha kinase GCN2. Genes Dev 17(7):859-72
Rodriguez-Hernandez CJ, et al.  (2003) The immunosuppressant FK506 uncovers a positive regulatory cross-talk between the Hog1p and Gcn2p pathways. J Biol Chem 278(36):33887-95
Garcia-Barrio M, et al.  (2002) Serine 577 is phosphorylated and negatively affects the tRNA binding and eIF2alpha kinase activities of GCN2. J Biol Chem 277(34):30675-83
Goossens A, et al.  (2001) The protein kinase Gcn2p mediates sodium toxicity in yeast. J Biol Chem 276(33):30753-60
Kubota H, et al.  (2001) Budding yeast GCN1 binds the GI domain to activate the eIF2alpha kinase GCN2. J Biol Chem 276(20):17591-6
Kubota H, et al.  (2000) GI domain-mediated association of the eukaryotic initiation factor 2alpha kinase GCN2 with its activator GCN1 is required for general amino acid control in budding yeast. J Biol Chem 275(27):20243-6
Sattlegger E and Hinnebusch AG  (2000) Separate domains in GCN1 for binding protein kinase GCN2 and ribosomes are required for GCN2 activation in amino acid-starved cells. EMBO J 19(23):6622-33
Yang R, et al.  (2000) Glucose limitation induces GCN4 translation by activation of Gcn2 protein kinase. Mol Cell Biol 20(8):2706-17
Donze O and Picard D  (1999) Hsp90 binds and regulates Gcn2, the ligand-inducible kinase of the alpha subunit of eukaryotic translation initiation factor 2 [corrected]. Mol Cell Biol 19(12):8422-32
Romano PR, et al.  (1998) Autophosphorylation in the activation loop is required for full kinase activity in vivo of human and yeast eukaryotic initiation factor 2alpha kinases PKR and GCN2. Mol Cell Biol 18(4):2282-97
Dever TE  (1997) Using GCN4 as a reporter of eIF2 alpha phosphorylation and translational regulation in yeast. Methods 11(4):403-17
Marton MJ, et al.  (1997) Evidence that GCN1 and GCN20, translational regulators of GCN4, function on elongating ribosomes in activation of eIF2alpha kinase GCN2. Mol Cell Biol 17(8):4474-89
Qian W, et al.  (1996) Expression of vaccinia virus K3L protein in yeast inhibits eukaryotic initiation factor-2 kinase GCN2 and the general amino acid control pathway. J Biol Chem 271(22):13202-7
Tavernarakis N and Thireos G  (1996) Genetic evidence for functional specificity of the yeast GCN2 kinase. Mol Gen Genet 251(5):613-8
Vazquez de Aldana CR, et al.  (1995) GCN20, a novel ATP binding cassette protein, and GCN1 reside in a complex that mediates activation of the eIF-2 alpha kinase GCN2 in amino acid-starved cells. EMBO J 14(13):3184-99
Wek SA, et al.  (1995) The histidyl-tRNA synthetase-related sequence in the eIF-2 alpha protein kinase GCN2 interacts with tRNA and is required for activation in response to starvation for different amino acids. Mol Cell Biol 15(8):4497-506
Marton MJ, et al.  (1993) GCN1, a translational activator of GCN4 in Saccharomyces cerevisiae, is required for phosphorylation of eukaryotic translation initiation factor 2 by protein kinase GCN2. Mol Cell Biol 13(6):3541-56
Results: 1 - 30 of 31 records
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