COB/Q0105 Literature Guide Help

Other names published for COB: COB1, CYTB, cytochrome b, Q0105

COB - Regulation of (36)

ReferenceOther Genes Addressed
Gruschke S, et al.  (2012) The Cbp3-Cbp6 complex coordinates cytochrome b synthesis with bc(1) complex assembly in yeast mitochondria. J Cell Biol 199(1):137-50
Moreno JI, et al.  (2012) Two independent activities define Ccm1p as a moonlighting protein in Saccharomyces cerevisiae. Biosci Rep 32(6):549-57
Vallieres C, et al.  (2012) HDQ, a potent inhibitor of Plasmodium falciparum proliferation, binds to the quinone reduction site of the cytochrome bc1 complex. Antimicrob Agents Chemother 56(7):3739-47
Choi JS, et al.  (2011) Caloric restriction improves efficiency and capacity of the mitochondrial electron transport chain in Saccharomyces cerevisiae. Biochem Biophys Res Commun 409(2):308-14
Josse L, et al.  (2011) Transcriptomic and phenotypic analysis of the effects of T-2 toxin on Saccharomyces cerevisiae: evidence of mitochondrial involvement. FEMS Yeast Res 11(1):133-50
Mathieu L, et al.  (2010) A mutational analysis reveals new functional interactions between domains of the Oxa1 protein in Saccharomyces cerevisiae. Mol Microbiol 75(2):474-88
Wang X, et al.  (2010) Combination of the loss of cmnm5U34 with the lack of s2U34 modifications of tRNALys, tRNAGlu, and tRNAGln altered mitochondrial biogenesis and respiration. J Mol Biol 395(5):1038-48
Bourges I, et al.  (2009) Multiple defects in the respiratory chain lead to the repression of genes encoding components of the respiratory chain and TCA cycle enzymes. J Mol Biol 387(5):1081-91
Covian R and Trumpower BL  (2009) Ilicicolin Inhibition and Binding at Center N of the Dimeric Cytochrome bc1 Complex Reveal Electron Transfer and Regulatory Interactions between Monomers. J Biol Chem 284(13):8614-20
Moreno JI, et al.  (2009) Ccm1p/Ygr150cp, a pentatricopeptide repeat protein, is essential to remove the fourth intron of both COB and COX1 pre-mRNAs in Saccharomyces cerevisiae. Curr Genet 55(4):475-84
Pan Y and Shadel GS  (2009) Extension of chronological life span by reduced TOR signaling requires down-regulation of Sch9p and involves increased mitochondrial OXPHOS complex density. Aging (Albany NY) 1(1):131-45
Claypool SM, et al.  (2008) Cardiolipin defines the interactome of the major ADP/ATP carrier protein of the mitochondrial inner membrane. J Cell Biol 182(5):937-50
Oliveira GA, et al.  (2008) Increased aerobic metabolism is essential for the beneficial effects of caloric restriction on yeast life span. J Bioenerg Biomembr 40(4):381-8
Ulanovskaya OA, et al.  (2008) Synthesis enables identification of the cellular target of leucascandrolide A and neopeltolide. Nat Chem Biol 4(7):418-24
Nowikovsky K, et al.  (2007) Mdm38 protein depletion causes loss of mitochondrial K(+)/H(+) exchange activity, osmotic swelling and mitophagy. Cell Death Differ 14(9):1647-56
Wang X, et al.  (2007) Deletion of the MTO2 gene related to tRNA modification causes a failure in mitochondrial RNA metabolism in the yeast Saccharomyces cerevisiae. FEBS Lett 581(22):4228-34
Wenz T, et al.  (2007) Mutational analysis of cytochrome b at the ubiquinol oxidation site of yeast complex III. J Biol Chem 282(6):3977-88
Bonawitz ND, et al.  (2006) Defective mitochondrial gene expression results in reactive oxygen species-mediated inhibition of respiration and reduction of yeast life span. Mol Cell Biol 26(13):4818-29
Solans A, et al.  (2006) Cytotoxicity of a mutant huntingtin fragment in yeast involves early alterations in mitochondrial OXPHOS complexes II and III. Hum Mol Genet 15(20):3063-81
Hall DA, et al.  (2004) Regulation of gene expression by a metabolic enzyme. Science 306(5695):482-4
Islas-Osuna MA, et al.  (2003) Suppressor mutations define two regions in the Cbp1 protein important for mitochondrial cytochrome b mRNA stability in Saccharomyces cerevisiae. Curr Genet 43(5):327-36
Islas-Osuna MA, et al.  (2002) Cbp1 is required for translation of the mitochondrial cytochrome b mRNA of Saccharomyces cerevisiae. J Biol Chem 277(41):37987-90
Trumpower BL  (2002) A concerted, alternating sites mechanism of ubiquinol oxidation by the dimeric cytochrome bc(1) complex. Biochim Biophys Acta 1555(1-3):166-73
Wang Y and Beattie DS  (2002) Molecular modeling studies of the DCCD-treated cytochrome bc1 complex: predicted conformational changes and inhibition of proton translocation. J Bioenerg Biomembr 34(2):81-8
Lee SY, et al.  (2001) The N-terminus of the Qcr7 protein of the cytochrome bc(1) complex in S. cerevisiae may be involved in facilitating stability of the subcomplex with the Qcr8 protein and cytochrome b. Arch Biochem Biophys 393(2):215-21
Stribinskis V, et al.  (2001) Rpm2, the protein subunit of mitochondrial RNase P in Saccharomyces cerevisiae, also has a role in the translation of mitochondrially encoded subunits of cytochrome c oxidase. Genetics 158(2):573-85
Guzelin E, et al.  (1996) Afg3p, a mitochondrial ATP-dependent metalloprotease, is involved in degradation of mitochondrially-encoded Cox1, Cox3, Cob, Su6, Su8 and Su9 subunits of the inner membrane complexes III, IV and V. FEBS Lett 381(1-2):42-6
Bonnefoy N, et al.  (1994) OXA1, a Saccharomyces cerevisiae nuclear gene whose sequence is conserved from prokaryotes to eukaryotes controls cytochrome oxidase biogenesis. J Mol Biol 239(2):201-12
Mayer SA and Dieckmann CL  (1989) The yeast CBP1 gene produces two differentially regulated transcripts by alternative 3'-end formation. Mol Cell Biol 9(10):4161-9
Kloeckener-Gruissem B, et al.  (1987) Nuclear functions required for cytochrome c oxidase biogenesis in Saccharomyces cerevisiae: multiple trans-acting nuclear genes exert specific effects on expression of each of the cytochrome c oxidase subunits encoded on mitochondrial DNA. Curr Genet 12(5):311-22