IRE1/YHR079C Literature Guide Help

Other names published for IRE1: ERN1, YHR079C

IRE1 - Regulation of (12)

ReferenceOther Genes Addressed
Rubio C, et al.  (2011) Homeostatic adaptation to endoplasmic reticulum stress depends on Ire1 kinase activity. J Cell Biol 193(1):171-84
Pincus D, et al.  (2010) BiP binding to the ER-stress sensor Ire1 tunes the homeostatic behavior of the unfolded protein response. PLoS Biol 8(7):e1000415
Wiseman RL, et al.  (2010) Flavonol activation defines an unanticipated ligand-binding site in the kinase-RNase domain of IRE1. Mol Cell 38(2):291-304
Korennykh AV, et al.  (2009) The unfolded protein response signals through high-order assembly of Ire1. Nature 457(7230):687-93
Kimata Y, et al.  (2007) Two regulatory steps of ER-stress sensor Ire1 involving its cluster formation and interaction with unfolded proteins. J Cell Biol 179(1):75-86
Jones DL, et al.  (2003) Transcriptome profiling of a Saccharomyces cerevisiae mutant with a constitutively activated Ras/cAMP pathway. Physiol Genomics 16(1):107-18
Kimata Y, et al.  (2003) Genetic evidence for a role of BiP/Kar2 that regulates Ire1 in response to accumulation of unfolded proteins. Mol Biol Cell 14(6):2559-69
Bonilla M, et al.  (2002) Essential role of calcineurin in response to endoplasmic reticulum stress. EMBO J 21(10):2343-53
Okamura K, et al.  (2000) Dissociation of Kar2p/BiP from an ER sensory molecule, Ire1p, triggers the unfolded protein response in yeast. Biochem Biophys Res Commun 279(2):445-50
Welihinda AA, et al.  (1998) Protein serine/threonine phosphatase Ptc2p negatively regulates the unfolded-protein response by dephosphorylating Ire1p kinase. Mol Cell Biol 18(4):1967-77
Shamu CE and Walter P  (1996) Oligomerization and phosphorylation of the Ire1p kinase during intracellular signaling from the endoplasmic reticulum to the nucleus. EMBO J 15(12):3028-39
Cao X, et al.  (1995) Requirement of tyrosine- and serine/threonine kinases in the transcriptional activation of the mammalian grp78/BiP promoter by thapsigargin. J Biol Chem 270(1):494-502