TOP2/YNL088W Literature Guide Help

Other names published for TOP2: TOR3, TRF3, DNA topoisomerase 2, YNL088W

TOP2 - Protein/Nucleic Acid Structure (9)

ReferenceOther Genes Addressed
Schmidt BH, et al.  (2012) Structure of a topoisomerase II-DNA-nucleotide complex reveals a new control mechanism for ATPase activity. Nat Struct Mol Biol 19(11):1147-54
Hardin AH, et al.  (2011) Direct measurement of DNA bending by type IIA topoisomerases: implications for non-equilibrium topology simplification. Nucleic Acids Res 39(13):5729-43
Schmidt BH, et al.  (2010) A novel and unified two-metal mechanism for DNA cleavage by type II and IA topoisomerases. Nature 465(7298):641-4
Dong KC and Berger JM  (2007) Structural basis for gate-DNA recognition and bending by type IIA topoisomerases. Nature 450(7173):1201-5
Suda N, et al.  (2004) The alpha4 residues of human DNA topoisomerase IIalpha function in enzymatic activity and anticancer drug sensitivity. Nucleic Acids Res 32(5):1767-73
Classen S, et al.  (2003) Structure of the topoisomerase II ATPase region and its mechanism of inhibition by the chemotherapeutic agent ICRF-187. Proc Natl Acad Sci U S A 100(19):10629-34
Heddle JG, et al.  (2001) The antibiotic microcin B17 is a DNA gyrase poison: characterisation of the mode of inhibition. J Mol Biol 307(5):1223-34
Strumberg D, et al.  (1999) Molecular analysis of yeast and human type II topoisomerases. Enzyme-DNA and drug interactions. J Biol Chem 274(40):28246-55
Berger JM, et al.  (1996) Structure and mechanism of DNA topoisomerase II. Nature 379(6562):225-32