ERG11/YHR007C Literature Guide Help

Other names published for ERG11: CYP51, sterol 14-demethylase, YHR007C

ERG11 - Protein/Nucleic Acid Structure (6)

ReferenceOther Genes Addressed
Hoepfner D, et al.  (2012) An integrated approach for identification and target validation of antifungal compounds active against Erg11p. Antimicrob Agents Chemother 56(8):4233-40
Lewis DF, et al.  (1999) Molecular modelling of lanosterol 14 alpha-demethylase (CYP51) from Saccharomyces cerevisiae via homology with CYP102, a unique bacterial cytochrome P450 isoform: quantitative structure-activity relationships (QSARs) within two related series of antifungal azole derivatives. J Enzyme Inhib 14(3):175-92
Boscott PE and Grant GH  (1994) Modeling cytochrome P450 14 alpha demethylase (Candida albicans) from P450cam. J Mol Graph 12(3):185-92, 195
Wright GD, et al.  (1990) Non-sterol structural probes of the lanosterol 14 alpha-demethylase from Saccharomyces cerevisiae. Biochim Biophys Acta 1040(1):95-101
Aoyama Y, et al.  (1989) The 3-hydroxy group of lanosterol is essential for orienting the substrate site of cytochrome P-450(14DM) (lanosterol 14 alpha- demethylase). Biochim Biophys Acta 1006(2):209-13
Ishida N, et al.  (1988) A single amino acid substitution converts cytochrome P450(14DM) to an inactive form, cytochrome P450SG1: complete primary structures deduced from cloned DNAS. Biochem Biophys Res Commun 155(1):317-23