RNR1/YER070W Literature Guide Help

Other names published for RNR1: CRT7, RIR1, SDS12, ribonucleotide-diphosphate reductase subunit RNR1, YER070W

RNR1 - Protein/Nucleic Acid Structure (11)

ReferenceOther Genes Addressed
Ahmad F, et al.  (2012) Role of arginine 293 and glutamine 288 in communication between catalytic and allosteric sites in yeast ribonucleotide reductase. J Mol Biol 419(5):315-29
Ahmad MF, et al.  (2012) Evaluating the therapeutic potential of a non-natural nucleotide that inhibits human ribonucleotide reductase. Mol Cancer Ther 11(10):2077-86
Fairman JW, et al.  (2011) Structural basis for allosteric regulation of human ribonucleotide reductase by nucleotide-induced oligomerization. Nat Struct Mol Biol 18(3):316-22
Roy S, et al.  (2009) Exploiting amino acid composition for predicting protein-protein interactions. PLoS One 4(11):e7813
Sun D, et al.  (2009) Structure-Based Design, Synthesis, and Evaluation of 2'-(2-Hydroxyethyl)-2'-deoxyadenosine and the 5'-Diphosphate Derivative as Ribonucleotide Reductase Inhibitors. ChemMedChem 4(10):1649-56
Cappellacci L, et al.  (2008) Ribose-Modified Purine Nucleosides as Ribonucleotide Reductase Inhibitors. Synthesis, Antitumor Activity, and Molecular Modeling of N(6)-Substituted 3'-C-Methyladenosine Derivatives. J Med Chem 51(14):4260-4269
Xu H, et al.  (2008) The Structural Basis for Peptidomimetic Inhibition of Eukaryotic Ribonucleotide Reductase: A Conformationally Flexible Pharmacophore. J Med Chem 51(15):4653-4659
Xu H, et al.  (2006) Structures of eukaryotic ribonucleotide reductase I define gemcitabine diphosphate binding and subunit assembly. Proc Natl Acad Sci U S A 103(11):4028-33
Xu H, et al.  (2006) Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation. Proc Natl Acad Sci U S A 103(11):4022-7
Fisher A, et al.  (1993) R2 C-terminal peptide inhibition of mammalian and yeast ribonucleotide reductase. J Med Chem 36(24):3859-62
Lammers M and Follmann H  (1984) Deoxyribonucleotide biosynthesis in yeast (Saccharomyces cerevisiae). A ribonucleotide reductase system of sufficient activity for DNA synthesis. Eur J Biochem 140(2):281-7