ORC6/YHR118C Literature Guide Help

Other names published for ORC6: origin recognition complex subunit 6, YHR118C

ORC6 - Protein-protein Interactions (24)

ReferenceOther Genes Addressed
Sun J, et al.  (2012) Cdc6-Induced Conformational Changes in ORC Bound to Origin DNA Revealed by Cryo-Electron Microscopy. Structure 20(3):534-44
Wu R, et al.  (2012) Cdt1p, through its interaction with Mcm6p, is required for the formation, nuclear accumulation and chromatin loading of the MCM complex. J Cell Sci 125(Pt 1):209-19
Chen S and Bell SP  (2011) CDK prevents Mcm2-7 helicase loading by inhibiting Cdt1 interaction with Orc6. Genes Dev 25(4):363-72
Takara TJ and Bell SP  (2011) Multiple Cdt1 molecules act at each origin to load replication-competent Mcm2-7 helicases. EMBO J 30(24):4885-96
Brooks MA, et al.  (2010) Systematic Bioinformatics and Experimental Validation of Yeast Complexes Reduces the Rate of Attrition during Structural Investigations. Structure 18(9):1075-82
Ma L, et al.  (2010) Identification of novel factors involved in or regulating initiation of DNA replication by a genome-wide phenotypic screen in Saccharomyces cerevisiae. Cell Cycle 9(21):4399-410
Muller P, et al.  (2010) The conserved bromo-adjacent homology domain of yeast Orc1 functions in the selection of DNA replication origins within chromatin. Genes Dev 24(13):1418-1433
Remus D, et al.  (2009) Concerted loading of Mcm2-7 double hexamers around DNA during DNA replication origin licensing. Cell 139(4):719-30
Chen Z, et al.  (2008) The architecture of the DNA replication origin recognition complex in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 105(30):10326-31
Kan J, et al.  (2008) Origin Recognition Complex (ORC) Mediates Histone 3 Lysine 4 Methylation through Cooperation with Spp1 in Saccharomyces cerevisiae. J Biol Chem 283(49):33803-7
Asano T, et al.  (2007) Interaction between ORC and Cdt1p of Saccharomyces cerevisiae. FEMS Yeast Res 7(8):1256-62
Chen S, et al.  (2007) Orc6 is required for dynamic recruitment of Cdt1 during repeated Mcm2 7 loading. Genes Dev 21(22):2897-2907
Matsuda K, et al.  (2007) Yeast two-hybrid analysis of the origin recognition complex of Saccharomyces cerevisiae: interaction between subunits and identification of binding proteins. FEMS Yeast Res 7(8):1263-9
Speck C and Stillman B  (2007) Cdc6 ATPase activity regulates ORC x Cdc6 stability and the selection of specific DNA sequences as origins of DNA replication. J Biol Chem 282(16):11705-14
Suter B, et al.  (2007) Association with the origin recognition complex suggests a novel role for histone acetyltransferase Hat1p/Hat2p. BMC Biol 5(1):38
Kawasaki Y, et al.  (2006) Reconstitution of Saccharomyces cerevisiae prereplicative complex assembly in vitro. Genes Cells 11(7):745-56
Archambault V, et al.  (2005) Disruption of mechanisms that prevent rereplication triggers a DNA damage response. Mol Cell Biol 25(15):6707-21
Archambault V, et al.  (2005) Two-faced cyclins with eyes on the targets. Cell Cycle 4(1):125-30
Mitkova AV, et al.  (2005) Modulation of DNA synthesis in Saccharomyces cerevisiae nuclear extract by DNA polymerases and the origin recognition complex. J Biol Chem 280(8):6285-92
Speck C, et al.  (2005) ATPase-dependent cooperative binding of ORC and Cdc6 to origin DNA. Nat Struct Mol Biol 12(11):965-71
Chastain PD 2nd, et al.  (2004) Mapping subunit location on the Saccharomyces cerevisiae origin recognition complex free and bound to DNA using a novel nanoscale biopointer. J Biol Chem 279(35):36354-62
Wilmes GM, et al.  (2004) Interaction of the S-phase cyclin Clb5 with an "RXL" docking sequence in the initiator protein Orc6 provides an origin-localized replication control switch. Genes Dev 18(9):981-91
Lee DG and Bell SP  (1997) Architecture of the yeast origin recognition complex bound to origins of DNA replication. Mol Cell Biol 17(12):7159-68
Bell SP, et al.  (1995) The multidomain structure of Orc1p reveals similarity to regulators of DNA replication and transcriptional silencing. Cell 83(4):563-8