Other names published for MCM5: BOB1, CDC46, YLR274W
MCM5 LITERATURE TOPICS
- Curated Literature
- Genetics/Cell Biology
- Nucleic Acid Information
- Gene Product Information
- Related Genes/Proteins
- Research Aids
- Genome-wide Analysis
- Proteome-wide Analysis
- Other Topics
- Additional Information
MCM5 - Protein-protein Interactions (31)
| Reference | Other Genes Addressed |
|---|---|
| Blitzblau HG, et al. (2012) Separation of DNA replication from the assembly of break-competent meiotic chromosomes. PLoS Genet 8(5):e1002643 | |
| Huo L, et al. (2012) The Rix1 (Ipi1p-2p-3p) complex is a critical determinant of DNA replication licensing independent of their roles in ribosome biogenesis. Cell Cycle 11(7):1325-39 | |
| van Deursen F, et al. (2012) Mcm10 associates with the loaded DNA helicase at replication origins and defines a novel step in its activation. EMBO J 31(9):2195-206 | |
| Bruck I and Kaplan DL (2011) GINS and Sld3 compete with one another for Mcm2-7 and Cdc45 binding. J Biol Chem 286(16):14157-67 | |
| Bruck I and Kaplan DL (2011) Origin single-stranded DNA releases Sld3 protein from the Mcm2-7 complex, allowing the GINS tetramer to bind the Mcm2-7 complex. J Biol Chem 286(21):18602-13 | |
| Bruck I, et al. (2011) Enabling association of the GINS protein tetramer with the mini chromosome maintenance (Mcm)2-7 protein complex by phosphorylated Sld2 protein and single-stranded origin DNA. J Biol Chem 286(42):36414-26 | |
| Takara TJ and Bell SP (2011) Multiple Cdt1 molecules act at each origin to load replication-competent Mcm2-7 helicases. EMBO J 30(24):4885-96 | |
| Bruck I and Kaplan D (2009) Dbf4-Cdc7 phosphorylation of Mcm2 is required for cell growth. J Biol Chem 284(42):28823-31 | |
| Evrin C, et al. (2009) A double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replication. Proc Natl Acad Sci U S A 106(48):20240-5 | |
| Francis LI, et al. (2009) Incorporation into the prereplicative complex activates the Mcm2-7 helicase for Cdc7-Dbf4 phosphorylation. Genes Dev 23(5):643-54 | |
| Gambus A, et al. (2009) A key role for Ctf4 in coupling the MCM2-7 helicase to DNA polymerase alpha within the eukaryotic replisome. EMBO J 28(19):2992-3004 | |
| Remus D, et al. (2009) Concerted loading of Mcm2-7 double hexamers around DNA during DNA replication origin licensing. Cell 139(4):719-30 | |
| Snyder M, et al. (2009) The Minichromosome Maintenance Proteins 2-7 (MCM2-7) Are Necessary for RNA Polymerase II (Pol II)-mediated Transcription. J Biol Chem 284(20):13466-72 | |
| Bochman ML, et al. (2008) Subunit organization of Mcm2-7 and the unequal role of active sites in ATP hydrolysis and viability. Mol Cell Biol 28(19):5865-73 | |
| Leon RP, et al. (2008) Functional Conservation of {beta}-Hairpin DNA Binding Domains in the Mcm Protein of Methanobacterium thermoautotrophicum and the Mcm5 protein of Saccharomyces cerevisiae. Genetics 179(4):1757-68 | |
| Bochman ML and Schwacha A (2007) Differences in the single-stranded DNA binding activities of MCM2-7 and MCM467: MCM2 and MCM5 define a slow ATP-dependent step. J Biol Chem 282(46):33795-804 | |
| Gambus A, et al. (2006) GINS maintains association of Cdc45 with MCM in replisome progression complexes at eukaryotic DNA replication forks. Nat Cell Biol 8(4):358-66 | |
| Kawasaki Y, et al. (2006) Reconstitution of Saccharomyces cerevisiae prereplicative complex assembly in vitro. Genes Cells 11(7):745-56 | |
| Sheu YJ and Stillman B (2006) Cdc7-Dbf4 phosphorylates MCM proteins via a docking site-mediated mechanism to promote S phase progression. Mol Cell 24(1):101-13 | |
| Wysocka M, et al. (2004) Saccharomyces cerevisiae CSM1 gene encoding a protein influencing chromosome segregation in meiosis I interacts with elements of the DNA replication complex. Exp Cell Res 294(2):592-602 | |
| Davey MJ, et al. (2003) Reconstitution of the Mcm2-7p heterohexamer, subunit arrangement, and ATP site architecture. J Biol Chem 278(7):4491-9 | |
| Tanaka S and Diffley JF (2002) Interdependent nuclear accumulation of budding yeast Cdt1 and Mcm2-7 during G1 phase. Nat Cell Biol 4(3):198-207 | |
| Schwacha A and Bell SP (2001) Interactions between two catalytically distinct MCM subgroups are essential for coordinated ATP hydrolysis and DNA replication. Mol Cell 8(5):1093-104 | |
| Feng L, et al. (2000) Loss control of Mcm5 interaction with chromatin in cdc6-1 mutated in CDC-NTP motif. DNA Cell Biol 19(7):447-57 | |
| Kawasaki Y, et al. (2000) Interactions between Mcm10p and other replication factors are required for proper initiation and elongation of chromosomal DNA replication in Saccharomyces cerevisiae. Genes Cells 5(12):975-89 | |
| Nguyen VQ, et al. (2000) Clb/Cdc28 kinases promote nuclear export of the replication initiator proteins Mcm2-7. Curr Biol 10(4):195-205 | |
| Zou L and Stillman B (1998) Formation of a preinitiation complex by S-phase cyclin CDK-dependent loading of Cdc45p onto chromatin. Science 280(5363):593-6 | |
| Dalton S and Hopwood B (1997) Characterization of Cdc47p-minichromosome maintenance complexes in Saccharomyces cerevisiae: identification of Cdc45p as a subunit. Mol Cell Biol 17(10):5867-75 | |
| Donovan S, et al. (1997) Cdc6p-dependent loading of Mcm proteins onto pre-replicative chromatin in budding yeast. Proc Natl Acad Sci U S A 94(11):5611-6 | |
| Hopwood B and Dalton S (1996) Cdc45p assembles into a complex with Cdc46p/Mcm5p, is required for minichromosome maintenance, and is essential for chromosomal DNA replication. Proc Natl Acad Sci U S A 93(22):12309-14 |




