TIM50/YPL063W Literature Guide Help

Other names published for TIM50: YPL063W

TIM50 - Protein-protein Interactions (23)

ReferenceOther Genes Addressed
Marom M, et al.  (2011) Direct interaction of mitochondrial targeting presequences with purified components of the TIM23 protein complex. J Biol Chem 286(51):43809-15
Qian X, et al.  (2011) Structural basis for the function of Tim50 in the mitochondrial presequence translocase. J Mol Biol 411(3):513-9
Schulz C, et al.  (2011) Tim50's presequence receptor domain is essential for signal driven transport across the TIM23 complex. J Cell Biol 195(4):643-56
Shiota T, et al.  (2011) In vivo protein-interaction mapping of a mitochondrial translocator protein Tom22 at work. Proc Natl Acad Sci U S A 108(37):15179-83
Chacinska A, et al.  (2010) Distinct forms of mitochondrial TOM-TIM supercomplexes define signal-dependent states of preprotein sorting. Mol Cell Biol 30(1):307-18
Sinha D, et al.  (2010) Role of Magmas in protein transport and human mitochondria biogenesis. Hum Mol Genet 19(7):1248-62
Gevorkyan-Airapetov L, et al.  (2009) Interaction of Tim23 with Tim50 Is Essential for Protein Translocation by the Mitochondrial TIM23 Complex. J Biol Chem 284(8):4865-72
Mokranjac D, et al.  (2009) Role of Tim50 in the transfer of precursor proteins from the outer to the inner membrane of mitochondria. Mol Biol Cell 20(5):1400-7
Tamura Y, et al.  (2009) Tim23-Tim50 pair coordinates functions of translocators and motor proteins in mitochondrial protein import. J Cell Biol 184(1):129-41
Tamura Y, et al.  (2009) Ups1p and Ups2p antagonistically regulate cardiolipin metabolism in mitochondria. J Cell Biol 185(6):1029-45
Alder NN, et al.  (2008) Quaternary structure of the mitochondrial TIM23 complex reveals dynamic association between Tim23p and other subunits. Mol Biol Cell 19(1):159-70
Dienhart MK and Stuart RA  (2008) The Yeast Aac2 Protein Exists in Physical Association with the Cytochrome bc1-COX Supercomplex and the TIM23 Machinery. Mol Biol Cell 19(9):3934-43
Popov-Celeketic D, et al.  (2008) Active remodelling of the TIM23 complex during translocation of preproteins into mitochondria. EMBO J 27(10):1469-80
Schiller D, et al.  (2008) Residues of Tim44 involved in both association with the translocon of the inner mitochondrial membrane and regulation of mitochondrial Hsp70 tethering. Mol Cell Biol 28(13):4424-33
van der Laan M, et al.  (2007) Motor-free mitochondrial presequence translocase drives membrane integration of preproteins. Nat Cell Biol 9(10):1152-9
Tamura Y, et al.  (2006) Identification of Tam41 maintaining integrity of the TIM23 protein translocator complex in mitochondria. J Cell Biol 174(5):631-7
van der Laan M, et al.  (2006) A role for Tim21 in membrane-potential-dependent preprotein sorting in mitochondria. Curr Biol 16(22):2271-6
Meier S, et al.  (2005) Conserved N-terminal negative charges in the Tim17 subunit of the TIM23 translocase play a critical role in the import of preproteins into mitochondria. J Biol Chem 280(9):7777-85
Mokranjac D, et al.  (2005) Role of Tim21 in mitochondrial translocation contact sites. J Biol Chem 280(25):23437-40
Yamano K, et al.  (2005) The phosphate carrier has an ability to be sorted to either the TIM22 pathway or the TIM23 pathway for its import into yeast mitochondria. J Biol Chem 280(11):10011-7
Geissler A, et al.  (2002) The mitochondrial presequence translocase: an essential role of Tim50 in directing preproteins to the import channel. Cell 111(4):507-18
Yamamoto H, et al.  (2002) Tim50 is a subunit of the TIM23 complex that links protein translocation across the outer and inner mitochondrial membranes. Cell 111(4):519-28
Schwartz MP and Matouschek A  (1999) The dimensions of the protein import channels in the outer and inner mitochondrial membranes. Proc Natl Acad Sci U S A 96(23):13086-90