SIR2/YDL042C Literature Guide Help

Other names published for SIR2: MAR1, YDL042C

SIR2 - Protein-protein Interactions (54)

ReferenceOther Genes Addressed
Ha CW, et al.  (2012) Nsi1 plays a significant role in the silencing of ribosomal DNA in Saccharomyces cerevisiae. Nucleic Acids Res 40(11):4892-903
Kueng S, et al.  (2012) Regulating repression: roles for the sir4 N-terminus in linker DNA protection and stabilization of epigenetic States. PLoS Genet 8(5):e1002727
Ehrentraut S, et al.  (2011) Structural basis for the role of the Sir3 AAA+ domain in silencing: interaction with Sir4 and unmethylated histone H3K79. Genes Dev 25(17):1835-46
Froyd CA and Rusche LN  (2011) The duplicated deacetylases Sir2 and Hst1 subfunctionalized by acquiring complementary inactivating mutations. Mol Cell Biol 31(16):3351-65
Wu CS, et al.  (2011) Targeted sister chromatid cohesion by sir2. PLoS Genet 7(2):e1002000
Bairwa NK, et al.  (2010) Replication fork arrest and rDNA silencing are two independent and separable functions of the replication terminator protein Fob1 of Saccharomyces cerevisiae. J Biol Chem 285(17):12612-9
Breitkreutz A, et al.  (2010) A global protein kinase and phosphatase interaction network in yeast. Science 328(5981):1043-6
Lynch PJ and Rusche LN  (2010) An auxiliary silencer and a boundary element maintain high levels of silencing proteins at HMR in Saccharomyces cerevisiae. Genetics 185(1):113-27
Rodriguez-Colman MJ, et al.  (2010) The forkhead transcription factor hcm1 promotes mitochondrial biogenesis and stress resistance in yeast. J Biol Chem 285(47):37092-101
Yu Q, et al.  (2010) Saccharomyces cerevisiae Esc2p Interacts with Sir2p through a Small Ubiquitin-like Modifier (SUMO)-binding Motif and Regulates Transcriptionally Silent Chromatin in a Locus-dependent Manner. J Biol Chem 285(10):7525-36
Jacobson S and Pillus L  (2009) The SAGA subunit Ada2 functions in transcriptional silencing. Mol Cell Biol 29(22):6033-45
Johnson A, et al.  (2009) Reconstitution of heterochromatin-dependent transcriptional gene silencing. Mol Cell 35(6):769-81
Koch MR and Pillus L  (2009) The glucanosyltransferase Gas1 functions in transcriptional silencing. Proc Natl Acad Sci U S A 106(27):11224-9
Liachko I and Tye BK  (2009) Mcm10 mediates the interaction between DNA replication and silencing machineries. Genetics 181(2):379-91
Martino F, et al.  (2009) Reconstitution of yeast silent chromatin: multiple contact sites and O-AADPR binding load SIR complexes onto nucleosomes in vitro. Mol Cell 33(3):323-34
Buchberger JR, et al.  (2008) Sir3-nucleosome interactions in spreading of silent chromatin in Saccharomyces cerevisiae. Mol Cell Biol 28(22):6903-18
Darst RP, et al.  (2008) Slx5 promotes transcriptional silencing and is required for robust growth in the absence of Sir2. Mol Cell Biol 28(4):1361-72
Altaf M, et al.  (2007) Interplay of chromatin modifiers on a short basic patch of histone H4 tail defines the boundary of telomeric heterochromatin. Mol Cell 28(6):1002-14
Hickman M, et al.  (2007) Isolation and Characterization of Conditional Alleles of the Yeast SIR2 Gene. J Mol Biol 367(5):1246-57
Hickman MA and Rusche LN  (2007) Substitution as a mechanism for genetic robustness: the duplicated deacetylases Hst1p and Sir2p in Saccharomyces cerevisiae. PLoS Genet 3(8):e126
Sung MK and Huh WK  (2007) Bimolecular fluorescence complementation analysis system for in vivo detection of protein-protein interaction in Saccharomyces cerevisiae. Yeast 24(9):767-75
Cubizolles F, et al.  (2006) A homotrimer-heterotrimer switch in Sir2 structure differentiates rDNA and telomeric silencing. Mol Cell 21(6):825-36
Huang J, et al.  (2006) Inhibition of homologous recombination by a cohesin-associated clamp complex recruited to the rDNA recombination enhancer. Genes Dev 20(20):2887-901
Matecic M, et al.  (2006) New alleles of SIR2 define cell-cycle-specific silencing functions. Genetics 173(4):1939-50
Douglas NL, et al.  (2005) Dual roles for Mcm10 in DNA replication initiation and silencing at the mating-type loci. Mol Biol Rep 32(4):197-204
Liachko I and Tye BK  (2005) Mcm10 is required for the maintenance of transcriptional silencing in Saccharomyces cerevisiae. Genetics 171(2):503-15
Liou GG, et al.  (2005) Assembly of the SIR complex and its regulation by O-acetyl-ADP-ribose, a product of NAD-dependent histone deacetylation. Cell 121(4):515-27
Millson SH, et al.  (2005) A two-hybrid screen of the yeast proteome for Hsp90 interactors uncovers a novel Hsp90 chaperone requirement in the activity of a stress-activated mitogen-activated protein kinase, Slt2p (Mpk1p). Eukaryot Cell 4(5):849-60
Rudner AD, et al.  (2005) A nonhistone protein-protein interaction required for assembly of the SIR complex and silent chromatin. Mol Cell Biol 25(11):4514-28
Tanny JC, et al.  (2004) Budding yeast silencing complexes and regulation of Sir2 activity by protein-protein interactions. Mol Cell Biol 24(16):6931-46