Other names published for CDC4: SCF ubiquitin ligase complex subunit CDC4, YFL009W
CDC4 LITERATURE TOPICS
- Curated Literature
- Genetics/Cell Biology
- Nucleic Acid Information
- Gene Product Information
- Related Genes/Proteins
- Research Aids
- Genome-wide Analysis
- Proteome-wide Analysis
- Other Topics
- Additional Information
CDC4 - Protein-protein Interactions (44)
| Reference | Other Genes Addressed |
|---|---|
| Landry BD, et al. (2012) F-box protein specificity for g1 cyclins is dictated by subcellular localization. PLoS Genet 8(7):e1002851 | |
| Tang X, et al. (2012) Composite low affinity interactions dictate recognition of the cyclin-dependent kinase inhibitor Sic1 by the SCFCdc4 ubiquitin ligase. Proc Natl Acad Sci U S A 109(9):3287-92 | |
| Bao MZ, et al. (2010) Multisite phosphorylation of the Saccharomyces cerevisiae filamentous growth regulator Tec1 is required for its recognition by the E3 ubiquitin ligase adaptor Cdc4 and its subsequent destruction in vivo. Eukaryot Cell 9(1):31-6 | |
| Cappell SD, et al. (2010) Systematic analysis of essential genes reveals important regulators of G protein signaling. Mol Cell 38(5):746-57 | |
| Kato M, et al. (2010) Remodeling of the SCF complex-mediated ubiquitination system by compositional alteration of incorporated F-box proteins. Proteomics 10(1):115-23 | |
| Mittag T, et al. (2010) Protein dynamics and conformational disorder in molecular recognition. J Mol Recognit 23(2):105-16 | |
| Mittag T, et al. (2010) Structure/function implications in a dynamic complex of the intrinsically disordered Sic1 with the Cdc4 subunit of an SCF ubiquitin ligase. Structure 18(4):494-506 | |
| Orlicky S, et al. (2010) An allosteric inhibitor of substrate recognition by the SCF(Cdc4) ubiquitin ligase. Nat Biotechnol 28(7):733-7 | |
| Drury LS and Diffley JF (2009) Factors affecting the diversity of DNA replication licensing control in eukaryotes. Curr Biol 19(6):530-5 | |
| Kishi T, et al. (2008) A refined two-hybrid system reveals that SCFCdc4-dependent degradation of Swi5 contributes to the regulatory mechanism of S-phase entry. Proc Natl Acad Sci U S A 105(38):14497-502 | |
| Mittag T, et al. (2008) Dynamic equilibrium engagement of a polyvalent ligand with a single-site receptor. Proc Natl Acad Sci U S A 105(46):17772-7 | |
| Borg M, et al. (2007) Polyelectrostatic interactions of disordered ligands suggest a physical basis for ultrasensitivity. Proc Natl Acad Sci U S A 104(23):9650-5 | |
| Hao B, et al. (2007) Structure of a Fbw7-Skp1-cyclin E complex: multisite-phosphorylated substrate recognition by SCF ubiquitin ligases. Mol Cell 26(1):131-43 | |
| Kishi T, et al. (2007) The SCFCdc4 ubiquitin ligase regulates calcineurin signaling through degradation of phosphorylated Rcn1, an inhibitor of calcineurin. Proc Natl Acad Sci U S A 104(44):17418-23 | |
| Pal B, et al. (2007) SCFCdc4-mediated degradation of the Hac1p transcription factor regulates the unfolded protein response in Saccharomyces cerevisiae. Mol Biol Cell 18(2):426-40 | |
| Weerasekera R, et al. (2007) Interactome and interface protocol (2IP): A novel strategy for high sensitivity topology mapping of protein complexes. Proteomics 7(21):3835-52 | |
| Chandrasekaran S, et al. (2006) Destabilization of binding to cofactors and SCFMet30 is the rate-limiting regulatory step in degradation of polyubiquitinated Met4. Mol Cell 24(5):689-99 | |
| Tagwerker C, et al. (2006) A tandem affinity tag for two-step purification under fully denaturing conditions: application in ubiquitin profiling and protein complex identification combined with in vivocross-linking. Mol Cell Proteomics 5(4):737-48 | |
| Wu X, et al. (2006) Prediction of yeast protein-protein interaction network: insights from the Gene Ontology and annotations. Nucleic Acids Res 34(7):2137-50 | |
| Tang X, et al. (2005) Genome-Wide Surveys for Phosphorylation-Dependent Substrates of SCF Ubiquitin Ligases. Methods Enzymol 399:433-58 | |
| Archambault V, et al. (2004) Targeted proteomic study of the cyclin-Cdk module. Mol Cell 14(6):699-711 | |
| Kus BM, et al. (2004) Functional interaction of 13 yeast SCF complexes with a set of yeast E2 enzymes in vitro. Proteins 54(3):455-67 | |
| Dixon C, et al. (2003) Overproduction of polypeptides corresponding to the amino terminus of the F-box proteins Cdc4p and Met30p inhibits ubiquitin ligase activities of their SCF complexes. Eukaryot Cell 2(1):123-33 | |
| Klein P, et al. (2003) Mathematical modeling suggests cooperative interactions between a disordered polyvalent ligand and a single receptor site. Curr Biol 13(19):1669-78 | |
| Orlicky S, et al. (2003) Structural basis for phosphodependent substrate selection and orientation by the SCFCdc4 ubiquitin ligase. Cell 112(2):243-56 | |
| Jager S, et al. (2001) Cic1, an adaptor protein specifically linking the 26S proteasome to its substrate, the SCF component Cdc4. EMBO J 20(16):4423-31 | |
| Jang SW, et al. (2001) Identification of Cdc6 protein domains involved in interaction with Mcm2 protein and Cdc4 protein in budding yeast cells. Biochem J 354(Pt 3):655-61 | |
| Mizunuma M, et al. (2001) GSK-3 kinase Mck1 and calcineurin coordinately mediate Hsl1 down-regulation by Ca2+ in budding yeast. EMBO J 20(5):1074-85 | |
| Nash P, et al. (2001) Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication. Nature 414(6863):514-21 | |
| Perkins G, et al. (2001) Separate SCF(CDC4) recognition elements target Cdc6 for proteolysis in S phase and mitosis. EMBO J 20(17):4836-45 |





