TIM44/YIL022W Literature Guide Help

Other names published for TIM44: ISP45, MIM44, MPI1, YIL022W

TIM44 - Protein-protein Interactions (54)

ReferenceOther Genes Addressed
Schilke BA, et al.  (2012) Genetic analysis of complex interactions among components of the mitochondrial import motor and translocon in Saccharomyces cerevisiae. Genetics 190(4):1341-53
Marom M, et al.  (2011) Direct interaction of mitochondrial targeting presequences with purified components of the TIM23 protein complex. J Biol Chem 286(51):43809-15
Pareek G, et al.  (2011) Primary sequence that determines the functional overlap between mitochondrial heat shock protein 70 Ssc1 and Ssc3 of Saccharomyces cerevisiae. J Biol Chem 286(21):19001-13
Popov-Celeketic D, et al.  (2011) Role of the import motor in insertion of transmembrane segments by the mitochondrial TIM23 complex. EMBO Rep 12(6):542-8
Blamowska M, et al.  (2010) ATPase domain and interdomain linker play a key role in aggregation of mitochondrial Hsp70 chaperone Ssc1. J Biol Chem 285(7):4423-31
Chacinska A, et al.  (2010) Distinct forms of mitochondrial TOM-TIM supercomplexes define signal-dependent states of preprotein sorting. Mol Cell Biol 30(1):307-18
Sinha D, et al.  (2010) Role of Magmas in protein transport and human mitochondria biogenesis. Hum Mol Genet 19(7):1248-62
Becker D, et al.  (2009) Impaired interdomain communication in mitochondrial Hsp70 results in the loss of inward-directed translocation force. J Biol Chem 284(5):2934-46
Dienhart MK and Stuart RA  (2008) The Yeast Aac2 Protein Exists in Physical Association with the Cytochrome bc1-COX Supercomplex and the TIM23 Machinery. Mol Biol Cell 19(9):3934-43
Hutu DP, et al.  (2008) Mitochondrial protein import motor: differential role of tim44 in the recruitment of pam17 and j-complex to the presequence translocase. Mol Biol Cell 19(6):2642-9
Popov-Celeketic D, et al.  (2008) Active remodelling of the TIM23 complex during translocation of preproteins into mitochondria. EMBO J 27(10):1469-80
Schiller D, et al.  (2008) Residues of Tim44 involved in both association with the translocon of the inner mitochondrial membrane and regulation of mitochondrial Hsp70 tethering. Mol Cell Biol 28(13):4424-33
Slutsky-Leiderman O, et al.  (2007) The interplay between components of the mitochondrial protein translocation motor studied using purified components. J Biol Chem 282(47):33935-42
Tamura Y, et al.  (2006) Identification of Tam41 maintaining integrity of the TIM23 protein translocator complex in mitochondria. J Cell Biol 174(5):631-7
van der Laan M, et al.  (2006) A role for Tim21 in membrane-potential-dependent preprotein sorting in mitochondria. Curr Biol 16(22):2271-6
Meier S, et al.  (2005) Conserved N-terminal negative charges in the Tim17 subunit of the TIM23 translocase play a critical role in the import of preproteins into mitochondria. J Biol Chem 280(9):7777-85
Mokranjac D, et al.  (2005) Role of Tim21 in mitochondrial translocation contact sites. J Biol Chem 280(25):23437-40
van der Laan M, et al.  (2005) Pam17 is required for architecture and translocation activity of the mitochondrial protein import motor. Mol Cell Biol 25(17):7449-58
D'Silva P, et al.  (2004) Regulated interactions of mtHsp70 with Tim44 at the translocon in the mitochondrial inner membrane. Nat Struct Mol Biol 11(11):1084-91
Frazier AE, et al.  (2004) Pam16 has an essential role in the mitochondrial protein import motor. Nat Struct Mol Biol 11(3):226-33
Kozany C, et al.  (2004) The J domain-related cochaperone Tim16 is a constituent of the mitochondrial TIM23 preprotein translocase. Nat Struct Mol Biol 11(3):234-41
Li Y, et al.  (2004) The presequence translocase-associated protein import motor of mitochondria. Pam16 functions in an antagonistic manner to Pam18. J Biol Chem 279(36):38047-54
D'Silva PD, et al.  (2003) J protein cochaperone of the mitochondrial inner membrane required for protein import into the mitochondrial matrix. Proc Natl Acad Sci U S A 100(24):13839-44
Liu Q, et al.  (2003) Regulated cycling of mitochondrial Hsp70 at the protein import channel. Science 300(5616):139-41
Mokranjac D, et al.  (2003) Tim14, a novel key component of the import motor of the TIM23 protein translocase of mitochondria. EMBO J 22(19):4945-56
Truscott KN, et al.  (2003) A J-protein is an essential subunit of the presequence translocase-associated protein import motor of mitochondria. J Cell Biol 163(4):707-13
Moro F, et al.  (2002) Mitochondrial protein import: molecular basis of the ATP-dependent interaction of MtHsp70 with Tim44. J Biol Chem 277(9):6874-80
Strub A, et al.  (2002) The Hsp70 peptide-binding domain determines the interaction of the ATPase domain with Tim44 in mitochondria. EMBO J 21(11):2626-35
Geissler A, et al.  (2001) Mitochondrial import driving forces: enhanced trapping by matrix Hsp70 stimulates translocation and reduces the membrane potential dependence of loosely folded preproteins. Mol Cell Biol 21(20):7097-104
Lutz T, et al.  (2001) The mitochondrial proteins Ssq1 and Jac1 are required for the assembly of iron sulfur clusters in mitochondria. J Mol Biol 307(3):815-25