VDE Literature Guide Help

Other names published for VDE: YDL184w-a, VDE1, YDL185W2, PI-SceI

VDE - Protein-Nucleic Acid Interactions (20)

ReferenceOther Genes Addressed
Fukuda T, et al.  (2006) Investigation of the mechanism of meiotic DNA cleavage by VMA1-derived endonuclease uncovers a meiotic alteration in chromatin structure around the target site. Eukaryot Cell 5(6):981-90
Noel AJ, et al.  (2004) DNA recognition by the homing endonuclease PI-SceI involves a divalent metal ion cofactor-induced conformational change. J Biol Chem 279(8):6794-804
Steuer S, et al.  (2004) Chimeras of the homing endonuclease PI-SceI and the homologous Candida tropicalis intein: a study to explore the possibility of exchanging DNA-binding modules to obtain highly specific endonucleases with altered specificity. Chembiochem 5(2):206-13
Gimble FS, et al.  (2003) Assessing the plasticity of DNA target site recognition of the PI-SceI homing endonuclease using a bacterial two-hybrid selection system. J Mol Biol 334(5):993-1008
Miyake T, et al.  (2003) Involvement of the VDE homing endonuclease and rapamycin in regulation of the Saccharomyces cerevisiae GSH11 gene encoding the high affinity glutathione transporter. J Biol Chem 278(41):39632-6
Posey KL and Gimble FS  (2002) Insertion of a reversible redox switch into a rare-cutting DNA endonuclease. Biochemistry 41(7):2184-90
Werner E, et al.  (2002) High resolution crystal structure of domain I of the Saccharomyces cerevisiae homing endonuclease PI-SceI. Nucleic Acids Res 30(18):3962-71
Gimble FS  (2001) Degeneration of a homing endonuclease and its target sequence in a wild yeast strain. Nucleic Acids Res 29(20):4215-23
Christ F, et al.  (2000) A model for the PI-SceIxDNA complex based on multiple base and phosphate backbone-specific photocross-links. J Mol Biol 300(4):867-75
Hu D, et al.  (2000) Probing the structure of the PI-SceI-DNA complex by affinity cleavage and affinity photocross-linking. J Biol Chem 275(4):2705-12
Wende W, et al.  (2000) [Analysis of binding and cleavage of DNA by the gene conversion PI-SCEI endonuclease using site-directed mutagenesis] Mol Biol (Mosk) 34(6):1054-64
Hu D, et al.  (1999) Mapping of a DNA binding region of the PI-sceI homing endonuclease by affinity cleavage and alanine-scanning mutagenesis. Biochemistry 38(39):12621-8
Miyamoto S, et al.  (1999) Recognition and cleavage of double-stranded DNA by yeast VMA1-derived endonuclease. Nucleic Acids Symp Ser (42):197-8
Pingoud V, et al.  (1999) Photocross-linking of the homing endonuclease PI-SceI to its recognition sequence. J Biol Chem 274(15):10235-43
Gimble FS, et al.  (1998) Identification of Lys-403 in the PI-SceI homing endonuclease as part of a symmetric catalytic center. J Biol Chem 273(46):30524-9
Grindl W, et al.  (1998) The protein splicing domain of the homing endonuclease PI-sceI is responsible for specific DNA binding. Nucleic Acids Res 26(8):1857-62
Pingoud V, et al.  (1998) Structural and functional analysis of the homing endonuclease PI-sceI by limited proteolytic cleavage and molecular cloning of partial digestion products. Biochemistry 37(22):8233-43
Gimble FS and Wang J  (1996) Substrate recognition and induced DNA distortion by the PI-SceI endonuclease, an enzyme generated by protein splicing. J Mol Biol 263(2):163-80
Wende W, et al.  (1996) Binding, bending and cleavage of DNA substrates by the homing endonuclease Pl-SceI. Nucleic Acids Res 24(21):4123-32
Gimble FS and Stephens BW  (1995) Substitutions in conserved dodecapeptide motifs that uncouple the DNA binding and DNA cleavage activities of PI-SceI endonuclease. J Biol Chem 270(11):5849-56