RAD50/YNL250W Literature Guide Help

Other names published for RAD50: YNL250W

RAD50 - Protein-Nucleic Acid Interactions (16)

ReferenceOther Genes Addressed
Fukunaga K, et al.  (2012) Subtelomere-binding protein Tbf1 and telomere-binding protein Rap1 collaborate to inhibit localization of the Mre11 complex to DNA ends in budding yeast. Mol Biol Cell 23(2):347-59
Tittel-Elmer M, et al.  (2012) Cohesin association to replication sites depends on rad50 and promotes fork restart. Mol Cell 48(1):98-108
McGee JS, et al.  (2010) Reduced Rif2 and lack of Mec1 target short telomeres for elongation rather than double-strand break repair. Nat Struct Mol Biol 17(12):1438-45
Tittel-Elmer M, et al.  (2009) The MRX complex stabilizes the replisome independently of the S phase checkpoint during replication stress. EMBO J 28(8):1142-56
Ghosal G and Muniyappa K  (2007) The Characterization of Saccharomyces cerevisiae Mre11/Rad50/Xrs2 Complex Reveals that Rad50 Negatively Regulates Mre11 Endonucleolytic but not the Exonucleolytic Activity. J Mol Biol 372(4):864-82
Hirano Y and Sugimoto K  (2007) Cdc13 telomere capping decreases Mec1 association but does not affect Tel1 association with DNA ends. Mol Biol Cell 18(6):2026-36
Lengsfeld BM, et al.  (2007) Sae2 Is an Endonuclease that Processes Hairpin DNA Cooperatively with the Mre11/Rad50/Xrs2 Complex. Mol Cell 28(4):638-51
Zhang Y, et al.  (2007) Role of Dnl4-Lif1 in nonhomologous end-joining repair complex assembly and suppression of homologous recombination. Nat Struct Mol Biol 14(7):639-46
Chen L, et al.  (2005) Effect of amino acid substitutions in the rad50 ATP binding domain on DNA double strand break repair in yeast. J Biol Chem 280(4):2620-7
Takata H, et al.  (2005) Late S phase-specific recruitment of Mre11 complex triggers hierarchical assembly of telomere replication proteins in Saccharomyces cerevisiae. Mol Cell 17(4):573-83
Trujillo KM, et al.  (2003) Yeast xrs2 binds DNA and helps target rad50 and mre11 to DNA ends. J Biol Chem 278(49):48957-64
Bucholc M, et al.  (2001) Intrachromatid excision of telomeric DNA as a mechanism for telomere size control in Saccharomyces cerevisiae. Mol Cell Biol 21(19):6559-73
Chen L, et al.  (2001) Promotion of Dnl4-catalyzed DNA end-joining by the Rad50/Mre11/Xrs2 and Hdf1/Hdf2 complexes. Mol Cell 8(5):1105-15
Trujillo KM and Sung P  (2001) DNA structure-specific nuclease activities in the Saccharomyces cerevisiae Rad50*Mre11 complex. J Biol Chem 276(38):35458-64
Ohta K, et al.  (1998) Mutations in the MRE11, RAD50, XRS2, and MRE2 genes alter chromatin configuration at meiotic DNA double-stranded break sites in premeiotic and meiotic cells. Proc Natl Acad Sci U S A 95(2):646-51
Raymond WE and Kleckner N  (1993) RAD50 protein of S.cerevisiae exhibits ATP-dependent DNA binding. Nucleic Acids Res 21(16):3851-6