PRP8/YHR165C Literature Guide Help

Other names published for PRP8: DBF3, DNA39, RNA8, SLT21, USA2, YHR165C

PRP8 - Protein-Nucleic Acid Interactions (22)

ReferenceOther Genes Addressed
Schwer B, et al.  (2011) Composition of yeast snRNPs and snoRNPs in the absence of trimethylguanosine caps reveals nuclear cap binding protein as a gained U1 component implicated in the cold-sensitivity of tgs1? cells. Nucleic Acids Res 39(15):6715-28
Kershaw CJ, et al.  (2009) Mutations in the U5 snRNA result in altered splicing of subsets of pre-mRNAs and reduced stability of Prp8. RNA 15(7):1292-304
Zhang L, et al.  (2009) Structural evidence for consecutive Hel308-like modules in the spliceosomal ATPase Brr2. Nat Struct Mol Biol 16(7):731-9
Pena V, et al.  (2008) Structure and function of an RNase H domain at the heart of the spliceosome. EMBO J 27(21):2929-40
Ritchie DB, et al.  (2008) Structural elucidation of a PRP8 core domain from the heart of the spliceosome. Nat Struct Mol Biol 15(11):1199-205
Schwer B  (2008) A conformational rearrangement in the spliceosome sets the stage for Prp22-dependent mRNA release. Mol Cell 30(6):743-54
Brenner TJ and Guthrie C  (2006) Assembly of Snu114 into U5 snRNP requires Prp8 and a functional GTPase domain. RNA 12(5):862-71
Turner IA, et al.  (2006) Dissection of Prp8 protein defines multiple interactions with crucial RNA sequences in the catalytic core of the spliceosome. RNA 12(3):375-86
Hertveldt K, et al.  (2003) Identification of Gal80p-interacting proteins by Saccharomyces cerevisiae whole genome phage display. Gene 307():141-9
McPheeters DS and Muhlenkamp P  (2003) Spatial organization of protein-RNA interactions in the branch site-3' splice site region during pre-mRNA splicing in yeast. Mol Cell Biol 23(12):4174-86
Dagher SF and Fu XD  (2001) Evidence for a role of Sky1p-mediated phosphorylation in 3' splice site recognition involving both Prp8 and Prp17/Slu4. RNA 7(9):1284-97
Collins CA and Guthrie C  (1999) Allele-specific genetic interactions between Prp8 and RNA active site residues suggest a function for Prp8 at the catalytic core of the spliceosome. Genes Dev 13(15):1970-82
Siatecka M, et al.  (1999) Functional interactions of Prp8 with both splice sites at the spliceosomal catalytic center. Genes Dev 13(15):1983-93
Vidal VP, et al.  (1999) Characterization of U6 snRNA-protein interactions. RNA 5(11):1470-81
Dix I, et al.  (1998) Protein-RNA interactions in the U5 snRNP of Saccharomyces cerevisiae. RNA 4(10):1239-50
Dix I, et al.  (1998) Protein-RNA interactions in the U5 snRNP of Saccharomyces cerevisiae. RNA 4(12):1675-86
Teigelkamp S, et al.  (1995) Extensive interactions of PRP8 protein with the 5' and 3' splice sites during splicing suggest a role in stabilization of exon alignment by U5 snRNA. EMBO J 14(11):2602-12
Teigelkamp S, et al.  (1995) Interaction of the yeast splicing factor PRP8 with substrate RNA during both steps of splicing. Nucleic Acids Res 23(3):320-6
Umen JG and Guthrie C  (1995) A novel role for a U5 snRNP protein in 3' splice site selection. Genes Dev 9(7):855-68
Umen JG and Guthrie C  (1995) Prp16p, Slu7p, and Prp8p interact with the 3' splice site in two distinct stages during the second catalytic step of pre-mRNA splicing. RNA 1(6):584-97
Whittaker E and Beggs JD  (1991) The yeast PRP8 protein interacts directly with pre-mRNA. Nucleic Acids Res 19(20):5483-9
Lossky M, et al.  (1987) Identification of a yeast snRNP protein and detection of snRNP-snRNP interactions. Cell 51(6):1019-26