MCM2/YBL023C Literature Guide Help

Other names published for MCM2: YBL023C

MCM2 - Protein-Nucleic Acid Interactions (28)

ReferenceOther Genes Addressed
Blitzblau HG, et al.  (2012) Separation of DNA replication from the assembly of break-competent meiotic chromosomes. PLoS Genet 8(5):e1002643
Wu R, et al.  (2012) Cdt1p, through its interaction with Mcm6p, is required for the formation, nuclear accumulation and chromatin loading of the MCM complex. J Cell Sci 125(Pt 1):209-19
Chen S and Bell SP  (2011) CDK prevents Mcm2-7 helicase loading by inhibiting Cdt1 interaction with Orc6. Genes Dev 25(4):363-72
Takara TJ and Bell SP  (2011) Multiple Cdt1 molecules act at each origin to load replication-competent Mcm2-7 helicases. EMBO J 30(24):4885-96
Tsakraklides V and Bell SP  (2010) Dynamics of pre-replicative complex assembly. J Biol Chem 285(13):9437-43
Bando M, et al.  (2009) Csm3, Tof1, and Mrc1 form a heterotrimeric mediator complex that associates with DNA replication forks. J Biol Chem 284(49):34355-65
Evrin C, et al.  (2009) A double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replication. Proc Natl Acad Sci U S A 106(48):20240-5
Francis LI, et al.  (2009) Incorporation into the prereplicative complex activates the Mcm2-7 helicase for Cdc7-Dbf4 phosphorylation. Genes Dev 23(5):643-54
Remus D, et al.  (2009) Concerted loading of Mcm2-7 double hexamers around DNA during DNA replication origin licensing. Cell 139(4):719-30
Stead BE, et al.  (2009) ATP binding and hydrolysis by Mcm2 regulate DNA binding by Mcm complexes. J Mol Biol 391(2):301-13
Yahyaoui W and Zannis-Hadjopoulos M  (2009) 14-3-3 proteins function in the initiation and elongation steps of DNA replication in Saccharomyces cerevisiae. J Cell Sci 122(Pt 24):4419-26
Bochman ML and Schwacha A  (2008) The Mcm2-7 complex has in vitro helicase activity. Mol Cell 31(2):287-93
Crampton A, et al.  (2008) An ARS element inhibits DNA replication through a SIR2-dependent mechanism. Mol Cell 30(2):156-66
Leon RP, et al.  (2008) Functional Conservation of {beta}-Hairpin DNA Binding Domains in the Mcm Protein of Methanobacterium thermoautotrophicum and the Mcm5 protein of Saccharomyces cerevisiae. Genetics 179(4):1757-68
Makise M, et al.  (2008) Analysis of Origin Recognition Complex in Saccharomyces cerevisiae by Use of Degron Mutants. J Biochem 143(4):455-65
Bochman ML and Schwacha A  (2007) Differences in the single-stranded DNA binding activities of MCM2-7 and MCM467: MCM2 and MCM5 define a slow ATP-dependent step. J Biol Chem 282(46):33795-804
Chen S, et al.  (2007) Orc6 is required for dynamic recruitment of Cdt1 during repeated Mcm2 7 loading. Genes Dev 21(22):2897-2907
Kawasaki Y, et al.  (2006) Reconstitution of Saccharomyces cerevisiae prereplicative complex assembly in vitro. Genes Cells 11(7):745-56
Randell JC, et al.  (2006) Sequential ATP hydrolysis by Cdc6 and ORC directs loading of the Mcm2-7 helicase. Mol Cell 21(1):29-39
Tanny RE, et al.  (2006) Genome-wide analysis of re-replication reveals inhibitory controls that target multiple stages of replication initiation. Mol Biol Cell 17(5):2415-23
Xu W, et al.  (2006) Genome-wide mapping of ORC and Mcm2p binding sites on tiling arrays and identification of essential ARS consensus sequences in S. cerevisiae. BMC Genomics 7():276
Yu L, et al.  (2006) A survey of essential gene function in the yeast cell division cycle. Mol Biol Cell 17(11):4736-47
Bowers JL, et al.  (2004) ATP hydrolysis by ORC catalyzes reiterative Mcm2-7 assembly at a defined origin of replication. Mol Cell 16(6):967-78
Ofir Y, et al.  (2004) The role and regulation of the preRC component Cdc6 in the initiation of premeiotic DNA replication. Mol Biol Cell 15(5):2230-42
Pramila T, et al.  (2002) Conserved homeodomain proteins interact with MADS box protein Mcm1 to restrict ECB-dependent transcription to the M/G1 phase of the cell cycle. Genes Dev 16(23):3034-45
Seki T and Diffley JF  (2000) Stepwise assembly of initiation proteins at budding yeast replication origins in vitro. Proc Natl Acad Sci U S A 97(26):14115-20
Zou L and Stillman B  (2000) Assembly of a complex containing Cdc45p, replication protein A, and Mcm2p at replication origins controlled by S-phase cyclin-dependent kinases and Cdc7p-Dbf4p kinase. Mol Cell Biol 20(9):3086-96
Yan H, et al.  (1993) Cell cycle-regulated nuclear localization of MCM2 and MCM3, which are required for the initiation of DNA synthesis at chromosomal replication origins in yeast. Genes Dev 7(11):2149-60