SET2/YJL168C Literature Guide Help

Other names published for SET2: EZL1, KMT3, YJL168C

SET2 - Protein Sequence Features (17)

ReferenceOther Genes Addressed
Fuchs SM, et al.  (2012) RNA polymerase II carboxyl-terminal domain phosphorylation regulates protein stability of the Set2 methyltransferase and histone H3 di- and trimethylation at lysine 36. J Biol Chem 287(5):3249-56
Wlodarski T, et al.  (2011) Comprehensive Structural and Substrate Specificity Classification of the Saccharomyces cerevisiae Methyltransferome. PLoS One 6(8):e23168
Yuan W, et al.  (2009) Heterogeneous Nuclear Ribonucleoprotein L Is a Subunit of Human KMT3a/Set2 Complex Required for H3 Lys-36 Trimethylation Activity in Vivo. J Biol Chem 284(23):15701-7
Du HN, et al.  (2008) Histone H3 K36 methylation is mediated by a trans-histone methylation pathway involving an interaction between Set2 and histone H4. Genes Dev 22(20):2786-98
Veerappan CS, et al.  (2008) Evolution of SET-domain protein families in the unicellular and multicellular Ascomycota fungi. BMC Evol Biol 8:190
Youdell ML, et al.  (2008) Roles for Ctk1 and Spt6 in regulating the different methylation states of histone H3 lysine 36. Mol Cell Biol 28(16):4915-26
Chu Y, et al.  (2006) The BUR1 cyclin-dependent protein kinase is required for the normal pattern of histone methylation by SET2. Mol Cell Biol 26(8):3029-38
Hesselberth JR, et al.  (2006) Comparative analysis of Saccharomyces cerevisiae WW domains and their interacting proteins. Genome Biol 7(4):R30
Tripic T, et al.  (2006) The Set2 methyltransferase associates with Ssn6 yet Tup1-Ssn6 repression is independent of histone methylation. Biochem Biophys Res Commun 339(3):905-14
Vojnic E, et al.  (2006) Structure and carboxyl-terminal domain (CTD) binding of the Set2 SRI domain that couples histone H3 Lys36 methylation to transcription. J Biol Chem 281(1):13-5
Kizer KO, et al.  (2005) A novel domain in Set2 mediates RNA polymerase II interaction and couples histone H3 K36 methylation with transcript elongation. Mol Cell Biol 25(8):3305-16
Boa S, et al.  (2003) Saccharomyces cerevisiae Set1p is a methyltransferase specific for lysine 4 of histone H3 and is required for efficient gene expression. Yeast 20(9):827-35
Krogan NJ, et al.  (2003) Methylation of histone H3 by Set2 in Saccharomyces cerevisiae is linked to transcriptional elongation by RNA polymerase II. Mol Cell Biol 23(12):4207-18
Landry J, et al.  (2003) Set2-catalyzed methylation of histone H3 represses basal expression of GAL4 in Saccharomyces cerevisiae. Mol Cell Biol 23(17):5972-8
Li J, et al.  (2002) Association of the histone methyltransferase Set2 with RNA polymerase II plays a role in transcription elongation. J Biol Chem 277(51):49383-8
Schneider R, et al.  (2002) Unsafe SETs: histone lysine methyltransferases and cancer. Trends Biochem Sci 27(8):396-402
Strahl BD, et al.  (2002) Set2 is a nucleosomal histone H3-selective methyltransferase that mediates transcriptional repression. Mol Cell Biol 22(5):1298-306