Other names published for RAD53: LSD1, MEC2, SPK1, YPL153C
RAD53 LITERATURE TOPICS
- Curated Literature
- Genetics/Cell Biology
- Nucleic Acid Information
- Gene Product Information
- Related Genes/Proteins
- Research Aids
- Genome-wide Analysis
- Proteome-wide Analysis
- Other Topics
- Additional Information
RAD53 - Protein Sequence Features (47)
| Reference | Other Genes Addressed |
|---|---|
| Jiao Y, et al. (2012) Surprising complexity of the Asf1 histone chaperone-Rad53 kinase interaction. Proc Natl Acad Sci U S A 109(8):2866-71 | |
| Manfrini N, et al. (2012) G(1)/S and G(2)/M cyclin-dependent kinase activities commit cells to death in the absence of the S-phase checkpoint. Mol Cell Biol 32(24):4971-85 | |
| Pershad K, et al. (2012) Directed evolution of the forkhead-associated domain to generate anti-phosphospecific reagents by phage display. J Mol Biol 424(1-2):88-103 | |
| Aucher W, et al. (2010) A Strategy for Interaction Site Prediction between Phospho-binding Modules and their Partners Identified from Proteomic Data. Mol Cell Proteomics 9(12):2745-59 | |
| Granata M, et al. (2010) Dynamics of Rad9 chromatin binding and checkpoint function are mediated by its dimerization and are cell cycle-regulated by CDK1 activity.LID - e1001047 [pii] PLoS Genet 6(8) | |
| Matsumura Y, et al. (2010) alpha-Helical burst on the folding pathway of FHA domains from Rad53 and Ki67. Biochimie 92(8):1031-9 | |
| Schleker T, et al. (2010) Cell cycle-dependent phosphorylation of Rad53 kinase by Cdc5 and Cdc28 modulates checkpoint adaptation. Cell Cycle 9(2):350-63 | |
| Vidanes GM, et al. (2010) CDC5 Inhibits the Hyperphosphorylation of the Checkpoint Kinase Rad53, Leading to Checkpoint Adaptation. PLoS Biol 8(1):e1000286 | |
| Chen SH and Zhou H (2009) Reconstitution of Rad53 Activation by Mec1 through Adaptor Protein Mrc1. J Biol Chem 284(28):18593-604 | |
| Diani L, et al. (2009) Saccharomyces CDK1 Phosphorylates Rad53 Kinase in Metaphase, Influencing Cellular Morphogenesis. J Biol Chem 284(47):32627-34 | |
| Feng W, et al. (2009) Centromere replication timing determines different forms of genomic instability in Saccharomyces cerevisiae checkpoint mutants during replication stress. Genetics 183(4):1249-60 | |
| Ohuchi T, et al. (2009) Accumulation of sumoylated Rad52 in checkpoint mutants perturbed in DNA replication. DNA Repair (Amst) 8(6):690-6 | |
| Fiorani S, et al. (2008) Characterization of the activation domain of the Rad53 checkpoint kinase. Cell Cycle 7(4):493-9 | |
| Jia-Lin Ma N and Stern DF (2008) Regulation of the Rad53 protein kinase in signal amplification by oligomer assembly and disassembly. Cell Cycle 7(6):808-17 | |
| Lee H, et al. (2008) Diphosphothreonine-specific interaction between an SQ/TQ cluster and an FHA domain in the Rad53-Dun1 kinase cascade. Mol Cell 30(6):767-78 | |
| Szyjka SJ, et al. (2008) Rad53 regulates replication fork restart after DNA damage in Saccharomyces cerevisiae. Genes Dev 22(14):1906-20 | |
| Tam AT, et al. (2008) Location-specific functions of the two forkhead-associated domains in rad53 checkpoint kinase signaling. Biochemistry 47(12):3912-6 | |
| Chen SH, et al. (2007) Mechanism of Dun1 activation by Rad53 phosphorylation in Saccharomyces cerevisiae. J Biol Chem 282(2):986-95 | |
| Guillemain G, et al. (2007) Mechanisms of checkpoint kinase Rad53 inactivation after a double-strand break in Saccharomyces cerevisiae. Mol Cell Biol 27(9):3378-89 | |
| Dohrmann PR and Sclafani RA (2006) Novel role for checkpoint Rad53 protein kinase in the initiation of chromosomal DNA replication in Saccharomyces cerevisiae. Genetics 174(1):87-99 | |
| Smolka MB, et al. (2006) An FHA domain-mediated protein interaction network of Rad53 reveals its role in polarized cell growth. J Cell Biol 175(5):743-53 | |
| Smolka MB, et al. (2005) Dynamic changes in protein-protein interaction and protein phosphorylation probed with amine-reactive isotope tag. Mol Cell Proteomics 4(9):1358-69 | |
| Sweeney FD, et al. (2005) Saccharomyces cerevisiae Rad9 acts as a Mec1 adaptor to allow Rad53 activation. Curr Biol 15(15):1364-75 | |
| Pike BL, et al. (2004) Mdt1, a novel Rad53 FHA1 domain-interacting protein, modulates DNA damage tolerance and G(2)/M cell cycle progression in Saccharomyces cerevisiae. Mol Cell Biol 24(7):2779-88 | |
| Pike BL, et al. (2004) Rad53 kinase activation-independent replication checkpoint function of the N-terminal forkhead-associated (FHA1) domain. J Biol Chem 279(38):39636-44 | |
| Yongkiettrakul S, et al. (2004) The ligand specificity of yeast Rad53 FHA domains at the +3 position is determined by nonconserved residues. Biochemistry 43(13):3862-9 | |
| Leroy C, et al. (2003) PP2C phosphatases Ptc2 and Ptc3 are required for DNA checkpoint inactivation after a double-strand break. Mol Cell 11(3):827-35 | |
| Pike BL, et al. (2003) Diverse but overlapping functions of the two forkhead-associated (FHA) domains in Rad53 checkpoint kinase activation. J Biol Chem 278(33):30421-4 | |
| Schwartz MF, et al. (2003) FHA domain-mediated DNA checkpoint regulation of Rad53. Cell Cycle 2(4):384-96 | |
| Scott KL and Plon SE (2003) Loss of Sin3/Rpd3 histone deacetylase restores the DNA damage response in checkpoint-deficient strains of Saccharomyces cerevisiae. Mol Cell Biol 23(13):4522-31 |





