PRP8/YHR165C Literature Guide Help

Other names published for PRP8: DBF3, DNA39, RNA8, SLT21, USA2, YHR165C

PRP8 - Protein Sequence Features (16)

ReferenceOther Genes Addressed
Dlakic M and Mushegian A  (2011) Prp8, the pivotal protein of the spliceosomal catalytic center, evolved from a retroelement-encoded reverse transcriptase. RNA 17(5):799-808
Weber G, et al.  (2011) Mechanism for Aar2p function as a U5 snRNP assembly factor. Genes Dev 25(15):1601-12
Grainger RJ, et al.  (2009) Physical and genetic interactions of yeast Cwc21p, an ortholog of human SRm300/SRRM2, suggest a role at the catalytic center of the spliceosome. RNA 15(12):2161-73
Maeder C, et al.  (2009) ATP-dependent unwinding of U4/U6 snRNAs by the Brr2 helicase requires the C terminus of Prp8. Nat Struct Mol Biol 16(1):42-8
Zhang L, et al.  (2009) Structural evidence for consecutive Hel308-like modules in the spliceosomal ATPase Brr2. Nat Struct Mol Biol 16(7):731-9
Pena V, et al.  (2008) Structure and function of an RNase H domain at the heart of the spliceosome. EMBO J 27(21):2929-40
Ritchie DB, et al.  (2008) Structural elucidation of a PRP8 core domain from the heart of the spliceosome. Nat Struct Mol Biol 15(11):1199-205
Yang K, et al.  (2008) Crystal structure of the {beta}-finger domain of Prp8 reveals analogy to ribosomal proteins. Proc Natl Acad Sci U S A 105(37):13817-22
Pena V, et al.  (2007) Structure of a multipartite protein-protein interaction domain in splicing factor prp8 and its link to retinitis pigmentosa. Mol Cell 25(4):615-24
Bellare P, et al.  (2006) Ubiquitin binding by a variant Jab1/MPN domain in the essential pre-mRNA splicing factor Prp8p. RNA 12(2):292-302
Boon KL, et al.  (2006) Prp8p dissection reveals domain structure and protein interaction sites. RNA 12(2):198-205
Turner IA, et al.  (2006) Dissection of Prp8 protein defines multiple interactions with crucial RNA sequences in the catalytic core of the spliceosome. RNA 12(3):375-86
Kofler M, et al.  (2005) GYF domain proteomics reveals interaction sites in known and novel target proteins. Mol Cell Proteomics 4(11):1797-811
Maytal-Kivity V, et al.  (2002) MPN+, a putative catalytic motif found in a subset of MPN domain proteins from eukaryotes and prokaryotes, is critical for Rpn11 function. BMC Biochem 3():28
Wiesner S, et al.  (2002) Solution structure and ligand recognition of the WW domain pair of the yeast splicing factor Prp40. J Mol Biol 324(4):807-22
Umen JG and Guthrie C  (1996) Mutagenesis of the yeast gene PRP8 reveals domains governing the specificity and fidelity of 3' splice site selection. Genetics 143(2):723-39