COB/Q0105 Literature Guide Help

Other names published for COB: COB1, CYTB, cytochrome b, Q0105

COB - Protein Sequence Features (30)

ReferenceOther Genes Addressed
Doggett JS, et al.  (2012) Endochin-like quinolones are highly efficacious against acute and latent experimental toxoplasmosis. Proc Natl Acad Sci U S A 109(39):15936-41
Vallieres C, et al.  (2012) HDQ, a potent inhibitor of Plasmodium falciparum proliferation, binds to the quinone reduction site of the cytochrome bc1 complex. Antimicrob Agents Chemother 56(7):3739-47
Hasan SS, et al.  (2011) Conservation of lipid functions in cytochrome bc complexes. J Mol Biol 414(1):145-62
Monzote L, et al.  (2011) Synthetic chromanol derivatives and their interaction with complex III in mitochondria from bovine, yeast, and Leishmania. Chem Res Toxicol 24(10):1678-85
Kokhan O, et al.  (2010) The binding interface of cytochrome c and cytochrome c in the bc complex: rationalizing the role of key residues. Biophys J 99(8):2647-56
Carbonell P, et al.  (2009) Energetic determinants of protein binding specificity: insights into protein interaction networks. Proteomics 9(7):1744-53
Covian R and Trumpower BL  (2009) The Rate-limiting Step in the Cytochrome bc1 Complex (Ubiquinol-Cytochrome c Oxidoreductase) Is Not Changed by Inhibition of Cytochrome b-dependent Deprotonation: IMPLICATIONS FOR THE MECHANISM OF UBIQUINOL OXIDATION AT CENTER P OF THE bc1 COMPLEX. J Biol Chem 284(21):14359-67
Ding MG, et al.  (2009) Combining Inhibitor Resistance-conferring Mutations in Cytochrome b Creates Conditional Synthetic Lethality in Saccharomyces cerevisiae. J Biol Chem 284(13):8478-85
Rotsaert FA, et al.  (2008) Mutations in cytochrome b that affect kinetics of the electron transfer reactions at center N in the yeast cytochrome bc(1) complex. Biochim Biophys Acta 1777(3):239-49
Seddiki N, et al.  (2008) Is Cytochrome b Glutamic Acid 272 a Quinol Binding Residue in the bc(1) Complex of Saccharomyces cerevisiae? Biochemistry 47(8):2357-68
Klingen AR, et al.  (2007) Redox-linked protonation state changes in cytochrome bc(1) identified by Poisson-Boltzmann electrostatics calculations. Biochim Biophys Acta 1767(3):204-21
Wenz T, et al.  (2007) Mutational analysis of cytochrome b at the ubiquinol oxidation site of yeast complex III. J Biol Chem 282(6):3977-88
Ding MG, et al.  (2006) Investigating the Qn site of the cytochrome bc1 complex in Saccharomyces cerevisiae with mutants resistant to ilicicolin H, a novel Qn site inhibitor. J Biol Chem 281(47):36036-43
Kessl JJ, et al.  (2006) Molecular basis of Toxoplasma gondii atovaquone resistance modeled in Saccharomyces cerevisiae. Mol Biochem Parasitol 146(2):255-8
Wenz T, et al.  (2006) Probing the role of E272 in quinol oxidation of mitochondrial complex III. Biochemistry 45(30):9042-52
Blakely EL, et al.  (2005) A mitochondrial cytochrome b mutation causing severe respiratory chain enzyme deficiency in humans and yeast. FEBS J 272(14):3583-92
Fisher N and Meunier B  (2005) Re-examination of inhibitor resistance conferred by Qo-site mutations in cytochrome b using yeast as a model system. Pest Manag Sci 61(10):973-8
Fisher N, et al.  (2004) Human disease-related mutations in cytochrome b studied in yeast. J Biol Chem 279(13):12951-8
Fisher N, et al.  (2004) Modeling the Qo site of crop pathogens in Saccharomyces cerevisiae cytochrome b. Eur J Biochem 271(11):2264-71
Kessl JJ, et al.  (2003) Molecular basis for atovaquone binding to the cytochrome bc1 complex. J Biol Chem 278(33):31312-8
Saint-Georges Y, et al.  (2002) A pathogenic cytochrome b mutation reveals new interactions between subunits of the mitochondrial bc1 complex. J Biol Chem 277(51):49397-402
Brasseur G, et al.  (2001) Analysis of suppressor mutation reveals long distance interactions in the bc(1) complex of Saccharomyces cerevisiae. Biochim Biophys Acta 1506(2):89-102
Bruel C, et al.  (1995) Role of the evolutionarily conserved cytochrome b tryptophan 142 in the ubiquinol oxidation catalyzed by the bc1 complex in the yeast Saccharomyces cerevisiae. J Biol Chem 270(38):22321-8
Lemesle-Meunier D, et al.  (1993) Cytochrome b-deficient mutants of the ubiquinol-cytochrome c oxidoreductase in Saccharomyces cerevisiae. Consequence for the functional and structural characteristics of the complex. J Biol Chem 268(21):15626-32
Tian GL, et al.  (1991) Incipient mitochondrial evolution in yeasts. II. The complete sequence of the gene coding for cytochrome b in Saccharomyces douglasii reveals the presence of both new and conserved introns and discloses major differences in the fixation of mutations in evolution. J Mol Biol 218(4):747-60
Tron T, et al.  (1991) Molecular analysis of revertants from a respiratory-deficient mutant affecting the center o domain of cytochrome b in Saccharomyces cerevisiae. FEBS Lett 278(1):26-30
di Rago JP, et al.  (1990) Intragenic suppressors reveal long distance interactions between inactivating and reactivating amino acid replacements generating three-dimensional constraints in the structure of mitochondrial cytochrome b. J Biol Chem 265(26):15750-7
Brasseur R  (1988) Calculation of the three-dimensional structure of Saccharomyces cerevisiae cytochrome b inserted in a lipid matrix. J Biol Chem 263(25):12571-5
di Rago JP and Colson AM  (1988) Molecular basis for resistance to antimycin and diuron, Q-cycle inhibitors acting at the Qi site in the mitochondrial ubiquinol-cytochrome c reductase in Saccharomyces cerevisiae. J Biol Chem 263(25):12564-70
Nobrega FG and Tzagoloff A  (1980) Assembly of the mitochondrial membrane system. DNA sequence and organization of the cytochrome b gene in Saccharomyces cerevisiae D273-10B. J Biol Chem 255(20):9828-37