VDE Literature Guide Help

Other names published for VDE: YDL184w-a, VDE1, YDL185W2, PI-SceI

VDE - Protein Sequence Features (26)

ReferenceOther Genes Addressed
Barzel A, et al.  (2011) Native homing endonucleases can target conserved genes in humans and in animal models. Nucleic Acids Res 39(15):6646-59
Bakhrat A, et al.  (2006) Nuclear import of ho endonuclease utilizes two nuclear localization signals and four importins of the ribosomal import system. J Biol Chem 281(18):12218-26
Butler MI, et al.  (2006) The distribution and evolutionary history of the PRP8 intein. BMC Evol Biol 6():42
Steuer S, et al.  (2004) Chimeras of the homing endonuclease PI-SceI and the homologous Candida tropicalis intein: a study to explore the possibility of exchanging DNA-binding modules to obtain highly specific endonucleases with altered specificity. Chembiochem 5(2):206-13
Koufopanou V, et al.  (2002) Adaptation for horizontal transfer in a homing endonuclease. Mol Biol Evol 19(3):239-46
Mizutani R, et al.  (2002) Protein-splicing reaction via a thiazolidine intermediate: crystal structure of the VMA1-derived endonuclease bearing the N and C-terminal propeptides. J Mol Biol 316(4):919-29
Werner E, et al.  (2002) High resolution crystal structure of domain I of the Saccharomyces cerevisiae homing endonuclease PI-SceI. Nucleic Acids Res 30(18):3962-71
Gimble FS  (2001) Degeneration of a homing endonuclease and its target sequence in a wild yeast strain. Nucleic Acids Res 29(20):4215-23
Christ F, et al.  (2000) A model for the PI-SceIxDNA complex based on multiple base and phosphate backbone-specific photocross-links. J Mol Biol 300(4):867-75
Hu D, et al.  (2000) Probing the structure of the PI-SceI-DNA complex by affinity cleavage and affinity photocross-linking. J Biol Chem 275(4):2705-12
Poland BW, et al.  (2000) Structural insights into the protein splicing mechanism of PI-SceI. J Biol Chem 275(22):16408-13
Christ F, et al.  (1999) The monomeric homing endonuclease PI-SceI has two catalytic centres for cleavage of the two strands of its DNA substrate. EMBO J 18(24):6908-16
Hu D, et al.  (1999) Mapping of a DNA binding region of the PI-sceI homing endonuclease by affinity cleavage and alanine-scanning mutagenesis. Biochemistry 38(39):12621-8
Pingoud V, et al.  (1999) Photocross-linking of the homing endonuclease PI-SceI to its recognition sequence. J Biol Chem 274(15):10235-43
Gimble FS, et al.  (1998) Identification of Lys-403 in the PI-SceI homing endonuclease as part of a symmetric catalytic center. J Biol Chem 273(46):30524-9
Nahon E and Raveh D  (1998) Targeting a truncated Ho-endonuclease of yeast to novel DNA sites with foreign zinc fingers. Nucleic Acids Res 26(5):1233-9
Pingoud V, et al.  (1998) Structural and functional analysis of the homing endonuclease PI-sceI by limited proteolytic cleavage and molecular cloning of partial digestion products. Biochemistry 37(22):8233-43
Chong S and Xu MQ  (1997) Protein splicing of the Saccharomyces cerevisiae VMA intein without the endonuclease motifs. J Biol Chem 272(25):15587-90
Duan X, et al.  (1997) Crystal structure of PI-SceI, a homing endonuclease with protein splicing activity. Cell 89(4):555-64
Kawasaki M, et al.  (1997) Identification of three core regions essential for protein splicing of the yeast Vma1 protozyme. A random mutagenesis study of the entire Vma1-derived endonuclease sequence. J Biol Chem 272(25):15668-74
Kawasaki M, et al.  (1997) Protein splicing in the yeast Vma1 protozyme: evidence for an intramolecular reaction. FEBS Lett 412(3):518-20
Nogami S, et al.  (1997) Probing novel elements for protein splicing in the yeast Vma1 protozyme: a study of replacement mutagenesis and intragenic suppression. Genetics 147(1):73-85
Kawasaki M, et al.  (1996) Folding-dependent in vitro protein splicing of the Saccharomyces cerevisiae VMA1 protozyme. Biochem Biophys Res Commun 222(3):827-32
Gimble FS and Stephens BW  (1995) Substitutions in conserved dodecapeptide motifs that uncouple the DNA binding and DNA cleavage activities of PI-SceI endonuclease. J Biol Chem 270(11):5849-56
Pietrokovski S  (1994) Conserved sequence features of inteins (protein introns) and their use in identifying new inteins and related proteins. Protein Sci 3(12):2340-50
Cooper AA, et al.  (1993) Protein splicing of the yeast TFP1 intervening protein sequence: a model for self-excision. EMBO J 12(6):2575-83